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A4XF23 (A4XF23_NOVAD) Unreviewed, UniProtKB/TrEMBL

Last modified December 11, 2013. Version 44. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein names
Gene names
Ordered Locus Names:Saro_3675 EMBL ABP64534.1
Encoded onPlasmid pNL2 Ref.2 EMBL ABP64534.1
OrganismNovosphingobium aromaticivorans (strain DSM 12444) [Complete proteome] [HAMAP] EMBL ABP64534.1
Taxonomic identifier279238 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaSphingomonadalesSphingomonadaceaeNovosphingobium

Protein attributes

Sequence length402 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Metal binding2101Magnesium PDB 2QJJ PDB 2QJM PDB 2QJN PDB 3R4E PDB 4K8G
Metal binding2361Magnesium PDB 2QJJ PDB 2QJM PDB 2QJN PDB 3R4E PDB 4K8G
Metal binding2621Magnesium PDB 2QJJ PDB 2QJM PDB 2QJN PDB 3R4E PDB 4K8G

Sequences

Sequence LengthMass (Da)Tools
A4XF23 [UniParc].

Last modified May 29, 2007. Version 1.
Checksum: E22007CDD0538750

FASTA40245,244
        10         20         30         40         50         60 
MKITAARVII TCPGRNFVTL KIETDQGVYG IGDATLNGRE LSVVAYLQEH VAPCLIGMDP 

        70         80         90        100        110        120 
RRIEDIWQYV YRGAYWRRGP VTMRAIAAVD MALWDIKAKM AGMPLYQLLG GRSRDGIMVY 

       130        140        150        160        170        180 
GHANGSDIAE TVEAVGHYID MGYKAIRAQT GVPGIKDAYG VGRGKLYYEP ADASLPSVTG 

       190        200        210        220        230        240 
WDTRKALNYV PKLFEELRKT YGFDHHLLHD GHHRYTPQEA ANLGKMLEPY QLFWLEDCTP 

       250        260        270        280        290        300 
AENQEAFRLV RQHTVTPLAV GEIFNTIWDA KDLIQNQLID YIRATVVGAG GLTHLRRIAD 

       310        320        330        340        350        360 
LASLYQVRTG CHGATDLSPV TMGCALHFDT WVPNFGIQEY MRHTEETDAV FPHDYWFEKG 

       370        380        390        400 
ELFVGETPGH GVDIDEELAA KYPYKPAYLP VARLEDGTMW NW 

« Hide

References

« Hide 'large scale' references
[1]"Evolution of enzymatic activities in the enolase superfamily: D-Mannonate dehydratase from Novosphingobium aromaticivorans."
Rakus J.F., Fedorov A.A., Fedorov E.V., Glasner M.E., Vick J.E., Babbitt P.C., Almo S.C., Gerlt J.A.
Biochemistry 46:12896-12908(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (1.80 ANGSTROMS) IN COMPLEX WITH MAGNESIUM.
[2]"Complete sequence of plasmid pNL2 of Novosphingobium aromaticivorans DSM 12444."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chertkov O., Han C., Thomson S., Schmutz J., Larimer F., Land M., Kyrpides N. expand/collapse author list , Ivanova N., Fredrickson J., Romine M.F., Richardson P.
Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DSM 12444 EMBL ABP64534.1.
[3]"Crystal structure of the A314P mutant of mannonate dehydratase from Novosphingobium aromaticivorans complexed with MG and D-mannonate."
Fedorov A.A., Fedorov E.V., Wichelecki D., Gerlt J.A., Almo S.C.
Submitted (MAR-2011) to the PDB data bank
Cited for: X-RAY CRYSTALLOGRAPHY (1.65 ANGSTROMS) IN COMPLEX WITH MAGNESIUM.
[4]"Crystal structure of D-Mannonate dehydratase from Novosphingobium aromaticivorans mutant (V161A, R163A, K165G, L166A, Y167G, Y168A, E169G)."
Wichelecki D., Lukk T., Nair S.K., Gerlt J.A.
Submitted (APR-2013) to the PDB data bank
Cited for: X-RAY CRYSTALLOGRAPHY (1.25 ANGSTROMS) IN COMPLEX WITH MAGNESIUM.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000677 Genomic DNA. Translation: ABP64534.1.
RefSeqYP_001166060.1. NC_009427.1.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
2QJJX-ray1.80A/B/C/D1-402[»]
2QJMX-ray2.20A/B/C/D1-402[»]
2QJNX-ray2.00A/B/C/D1-402[»]
3R4EX-ray1.65A/B/C/D1-402[»]
4K8GX-ray1.25A1-402[»]
ProteinModelPortalA4XF23.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING279238.Saro_3675.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABP64534; ABP64534; Saro_3675.
GeneID5077823.
KEGGnar:Saro_3675.
PATRIC22790486. VBINovAro50627_3893.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG4948.
HOGENOMHOG000113758.
KOK08323.
OMAIRAQSGV.
OrthoDBEOG6SBSZM.
ProtClustDBPRK15072.

Enzyme and pathway databases

BioCycNARO279238:GHBU-3686-MONOMER.

Family and domain databases

InterProIPR018110. Mandel_Rmase/mucon_lact_enz_CS.
IPR013342. Mandelate_racemase_C.
IPR013341. Mandelate_racemase_N.
IPR001354. MR_MLE.
[Graphical view]
PANTHERPTHR13794. PTHR13794. 1 hit.
PfamPF01188. MR_MLE. 1 hit.
PF02746. MR_MLE_N. 1 hit.
[Graphical view]
SMARTSM00922. MR_MLE. 1 hit.
[Graphical view]
PROSITEPS00908. MR_MLE_1. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

EvolutionaryTraceA4XF23.

Entry information

Entry nameA4XF23_NOVAD
AccessionPrimary (citable) accession number: A4XF23
Entry history
Integrated into UniProtKB/TrEMBL: May 29, 2007
Last sequence update: May 29, 2007
Last modified: December 11, 2013
This is version 44 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)