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A4XDR3

- PGK_SALTO

UniProt

A4XDR3 - PGK_SALTO

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Protein
Phosphoglycerate kinase
Gene
pgk, Strop_3097
Organism
Salinispora tropica (strain ATCC BAA-916 / DSM 44818 / CNB-440)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei41 – 411Substrate By similarity
Binding sitei123 – 1231Substrate By similarity
Binding sitei160 – 1601Substrate By similarity
Binding sitei210 – 2101ATP By similarity
Binding sitei298 – 2981ATP; via carbonyl oxygen By similarity
Binding sitei329 – 3291ATP By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi355 – 3584ATP By similarity

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. phosphoglycerate kinase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase

Keywords - Biological processi

Glycolysis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciSTRO369723:GI49-3132-MONOMER.
UniPathwayiUPA00109; UER00185.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoglycerate kinase (EC:2.7.2.3)
Gene namesi
Name:pgk
Ordered Locus Names:Strop_3097
OrganismiSalinispora tropica (strain ATCC BAA-916 / DSM 44818 / CNB-440)
Taxonomic identifieri369723 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesMicromonosporineaeMicromonosporaceaeSalinispora
ProteomesiUP000000235: Chromosome

Subcellular locationi

Cytoplasm Reviewed prediction UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 399399Phosphoglycerate kinaseUniRule annotation
PRO_1000076605Add
BLAST

Interactioni

Subunit structurei

Monomer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi369723.Strop_3097.

Structurei

3D structure databases

ProteinModelPortaliA4XDR3.
SMRiA4XDR3. Positions 4-399.

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni24 – 263Substrate binding By similarity
Regioni64 – 674Substrate binding By similarity

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0126.
HOGENOMiHOG000227108.
KOiK00927.
OMAiHASVYDI.
OrthoDBiEOG64N9Z0.

Family and domain databases

Gene3Di3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPiMF_00145. Phosphoglyc_kinase.
InterProiIPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015911. Phosphoglycerate_kinase_CS.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view]
PANTHERiPTHR11406. PTHR11406. 1 hit.
PfamiPF00162. PGK. 1 hit.
[Graphical view]
PIRSFiPIRSF000724. Pgk. 1 hit.
PRINTSiPR00477. PHGLYCKINASE.
SUPFAMiSSF53748. SSF53748. 1 hit.
PROSITEiPS00111. PGLYCERATE_KINASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A4XDR3-1 [UniParc]FASTAAdd to Basket

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MTIRTLDDLL AEEVTGRRVL VRADLNVPLD KQTGQIADDG RIRAVLPTLS    50
ALVQAGAKVV VCSHLGRPKG SPNPVFSLRP VAGRLGELLG APVHFAEDTV 100
GDSARSTVAD LADGQVALLE NLRFNPGETS KDEAERGAFA DQLAALADAY 150
VDDAFGAVHR RHASVYDVPA RLPHVAGRLV LREVEVLGTL AGEPDRPYVV 200
VLGGSKVSDK LAVIEALLPK VDRLLVGGGM CFTFLKAQGH EVGSSLLEEE 250
MVETCRSLLE RADGKIMLPV DVVAADAFAP DAPHDTVRAD GIPSKRVGLD 300
IGPETVAGFA AALRGARTIF WNGPMGVFEM AAFAHGTRGV AEAIATSDAF 350
TVVGGGDSAA AVRALGLDEQ AFSHISTGGG ASLEYLEGKT LPGIAALES 399
Length:399
Mass (Da):41,617
Last modified:May 29, 2007 - v1
Checksum:i28497D5C9029994B
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000667 Genomic DNA. Translation: ABP55534.1.
RefSeqiYP_001159912.1. NC_009380.1.

Genome annotation databases

EnsemblBacteriaiABP55534; ABP55534; Strop_3097.
GeneIDi5059561.
KEGGistp:Strop_3097.
PATRICi23445292. VBISalTro43511_3187.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000667 Genomic DNA. Translation: ABP55534.1 .
RefSeqi YP_001159912.1. NC_009380.1.

3D structure databases

ProteinModelPortali A4XDR3.
SMRi A4XDR3. Positions 4-399.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 369723.Strop_3097.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABP55534 ; ABP55534 ; Strop_3097 .
GeneIDi 5059561.
KEGGi stp:Strop_3097.
PATRICi 23445292. VBISalTro43511_3187.

Phylogenomic databases

eggNOGi COG0126.
HOGENOMi HOG000227108.
KOi K00927.
OMAi HASVYDI.
OrthoDBi EOG64N9Z0.

Enzyme and pathway databases

UniPathwayi UPA00109 ; UER00185 .
BioCyci STRO369723:GI49-3132-MONOMER.

Family and domain databases

Gene3Di 3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPi MF_00145. Phosphoglyc_kinase.
InterProi IPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015911. Phosphoglycerate_kinase_CS.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view ]
PANTHERi PTHR11406. PTHR11406. 1 hit.
Pfami PF00162. PGK. 1 hit.
[Graphical view ]
PIRSFi PIRSF000724. Pgk. 1 hit.
PRINTSi PR00477. PHGLYCKINASE.
SUPFAMi SSF53748. SSF53748. 1 hit.
PROSITEi PS00111. PGLYCERATE_KINASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Complete sequence of Salinispora tropica CNB-440."
    Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Sun H., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Jensen P.R., Moore B.S., Udwary D.W., Richardson P.
    Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC BAA-916 / DSM 44818 / CNB-440.

Entry informationi

Entry nameiPGK_SALTO
AccessioniPrimary (citable) accession number: A4XDR3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: May 29, 2007
Last modified: June 11, 2014
This is version 50 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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