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A4XDR3 (PGK_SALTO) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 50. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Phosphoglycerate kinase

EC=2.7.2.3
Gene names
Name:pgk
Ordered Locus Names:Strop_3097
OrganismSalinispora tropica (strain ATCC BAA-916 / DSM 44818 / CNB-440) [Complete proteome] [HAMAP]
Taxonomic identifier369723 [NCBI]
Taxonomic lineageBacteriaActinobacteriaActinobacteridaeActinomycetalesMicromonosporineaeMicromonosporaceaeSalinispora

Protein attributes

Sequence length399 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate. HAMAP-Rule MF_00145

Pathway

Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 2/5. HAMAP-Rule MF_00145

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00145

Subcellular location

Cytoplasm Potential HAMAP-Rule MF_00145.

Sequence similarities

Belongs to the phosphoglycerate kinase family.

Ontologies

Keywords
   Biological processGlycolysis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processglycolytic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

phosphoglycerate kinase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 399399Phosphoglycerate kinase HAMAP-Rule MF_00145
PRO_1000076605

Regions

Nucleotide binding355 – 3584ATP By similarity
Region24 – 263Substrate binding By similarity
Region64 – 674Substrate binding By similarity

Sites

Binding site411Substrate By similarity
Binding site1231Substrate By similarity
Binding site1601Substrate By similarity
Binding site2101ATP By similarity
Binding site2981ATP; via carbonyl oxygen By similarity
Binding site3291ATP By similarity

Sequences

Sequence LengthMass (Da)Tools
A4XDR3 [UniParc].

Last modified May 29, 2007. Version 1.
Checksum: 28497D5C9029994B

FASTA39941,617
        10         20         30         40         50         60 
MTIRTLDDLL AEEVTGRRVL VRADLNVPLD KQTGQIADDG RIRAVLPTLS ALVQAGAKVV 

        70         80         90        100        110        120 
VCSHLGRPKG SPNPVFSLRP VAGRLGELLG APVHFAEDTV GDSARSTVAD LADGQVALLE 

       130        140        150        160        170        180 
NLRFNPGETS KDEAERGAFA DQLAALADAY VDDAFGAVHR RHASVYDVPA RLPHVAGRLV 

       190        200        210        220        230        240 
LREVEVLGTL AGEPDRPYVV VLGGSKVSDK LAVIEALLPK VDRLLVGGGM CFTFLKAQGH 

       250        260        270        280        290        300 
EVGSSLLEEE MVETCRSLLE RADGKIMLPV DVVAADAFAP DAPHDTVRAD GIPSKRVGLD 

       310        320        330        340        350        360 
IGPETVAGFA AALRGARTIF WNGPMGVFEM AAFAHGTRGV AEAIATSDAF TVVGGGDSAA 

       370        380        390 
AVRALGLDEQ AFSHISTGGG ASLEYLEGKT LPGIAALES 

« Hide

References

[1]"Complete sequence of Salinispora tropica CNB-440."
Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Sun H., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Jensen P.R., Moore B.S., Udwary D.W., Richardson P.
Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC BAA-916 / DSM 44818 / CNB-440.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000667 Genomic DNA. Translation: ABP55534.1.
RefSeqYP_001159912.1. NC_009380.1.

3D structure databases

ProteinModelPortalA4XDR3.
SMRA4XDR3. Positions 4-399.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING369723.Strop_3097.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABP55534; ABP55534; Strop_3097.
GeneID5059561.
KEGGstp:Strop_3097.
PATRIC23445292. VBISalTro43511_3187.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0126.
HOGENOMHOG000227108.
KOK00927.
OMAHASVYDI.
OrthoDBEOG64N9Z0.

Enzyme and pathway databases

BioCycSTRO369723:GI49-3132-MONOMER.
UniPathwayUPA00109; UER00185.

Family and domain databases

Gene3D3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPMF_00145. Phosphoglyc_kinase.
InterProIPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015911. Phosphoglycerate_kinase_CS.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view]
PANTHERPTHR11406. PTHR11406. 1 hit.
PfamPF00162. PGK. 1 hit.
[Graphical view]
PIRSFPIRSF000724. Pgk. 1 hit.
PRINTSPR00477. PHGLYCKINASE.
SUPFAMSSF53748. SSF53748. 1 hit.
PROSITEPS00111. PGLYCERATE_KINASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePGK_SALTO
AccessionPrimary (citable) accession number: A4XDR3
Entry history
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: May 29, 2007
Last modified: June 11, 2014
This is version 50 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways