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A4XDK4

- RNPA_SALTO

UniProt

A4XDK4 - RNPA_SALTO

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Protein

Ribonuclease P protein component

Gene

rnpA

Organism
Salinispora tropica (strain ATCC BAA-916 / DSM 44818 / CNB-440)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.UniRule annotation

Catalytic activityi

Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor.UniRule annotation

GO - Molecular functioni

  1. ribonuclease P activity Source: UniProtKB-EC
  2. tRNA binding Source: InterPro

GO - Biological processi

  1. tRNA processing Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Endonuclease, Hydrolase, Nuclease

Keywords - Biological processi

tRNA processing

Keywords - Ligandi

RNA-binding

Enzyme and pathway databases

BioCyciSTRO369723:GI49-4653-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Ribonuclease P protein componentUniRule annotation (EC:3.1.26.5UniRule annotation)
Short name:
RNase P proteinUniRule annotation
Short name:
RNaseP proteinUniRule annotation
Alternative name(s):
Protein C5UniRule annotation
Gene namesi
Name:rnpAUniRule annotation
Ordered Locus Names:Strop_4592
OrganismiSalinispora tropica (strain ATCC BAA-916 / DSM 44818 / CNB-440)
Taxonomic identifieri369723 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesMicromonosporineaeMicromonosporaceaeSalinispora
ProteomesiUP000000235: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 136136Ribonuclease P protein componentPRO_1000078207Add
BLAST

Interactioni

Subunit structurei

Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.UniRule annotation

Protein-protein interaction databases

STRINGi369723.Strop_4592.

Structurei

3D structure databases

ProteinModelPortaliA4XDK4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the RnpA family.UniRule annotation

Phylogenomic databases

eggNOGiNOG299111.
HOGENOMiHOG000266301.
KOiK03536.
OMAiMLPTENR.
OrthoDBiEOG6XWV8K.

Family and domain databases

Gene3Di3.30.230.10. 1 hit.
HAMAPiMF_00227. RNase_P.
InterProiIPR020568. Ribosomal_S5_D2-typ_fold.
IPR014721. Ribosomal_S5_D2-typ_fold_subgr.
IPR000100. RNase_P.
IPR020539. RNase_P_CS.
[Graphical view]
PfamiPF00825. Ribonuclease_P. 1 hit.
[Graphical view]
SUPFAMiSSF54211. SSF54211. 1 hit.
TIGRFAMsiTIGR00188. rnpA. 1 hit.
PROSITEiPS00648. RIBONUCLEASE_P. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A4XDK4 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MLTAAQRLRR STDFAAAVRG GRRVGRGVVV VHLTLPGTLP DVSSSKPARD
60 70 80 90 100
TGAEQTSAPA RAGFVVSKAV GNAVVRNAVR RRLRHLVRER LPGLPAGSTL
110 120 130
VVRALPTAAH RSYQRLGVDL DAAIAAARAP RGRRSR
Length:136
Mass (Da):14,428
Last modified:May 29, 2007 - v1
Checksum:i55DF82EF470E51B3
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000667 Genomic DNA. Translation: ABP57020.1.
RefSeqiYP_001161398.1. NC_009380.1.

Genome annotation databases

EnsemblBacteriaiABP57020; ABP57020; Strop_4592.
GeneIDi5061082.
KEGGistp:Strop_4592.
PATRICi23448470. VBISalTro43511_4751.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000667 Genomic DNA. Translation: ABP57020.1 .
RefSeqi YP_001161398.1. NC_009380.1.

3D structure databases

ProteinModelPortali A4XDK4.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 369723.Strop_4592.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABP57020 ; ABP57020 ; Strop_4592 .
GeneIDi 5061082.
KEGGi stp:Strop_4592.
PATRICi 23448470. VBISalTro43511_4751.

Phylogenomic databases

eggNOGi NOG299111.
HOGENOMi HOG000266301.
KOi K03536.
OMAi MLPTENR.
OrthoDBi EOG6XWV8K.

Enzyme and pathway databases

BioCyci STRO369723:GI49-4653-MONOMER.

Family and domain databases

Gene3Di 3.30.230.10. 1 hit.
HAMAPi MF_00227. RNase_P.
InterProi IPR020568. Ribosomal_S5_D2-typ_fold.
IPR014721. Ribosomal_S5_D2-typ_fold_subgr.
IPR000100. RNase_P.
IPR020539. RNase_P_CS.
[Graphical view ]
Pfami PF00825. Ribonuclease_P. 1 hit.
[Graphical view ]
SUPFAMi SSF54211. SSF54211. 1 hit.
TIGRFAMsi TIGR00188. rnpA. 1 hit.
PROSITEi PS00648. RIBONUCLEASE_P. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Complete sequence of Salinispora tropica CNB-440."
    Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Sun H., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Jensen P.R., Moore B.S., Udwary D.W., Richardson P.
    Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC BAA-916 / DSM 44818 / CNB-440.

Entry informationi

Entry nameiRNPA_SALTO
AccessioniPrimary (citable) accession number: A4XDK4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: May 29, 2007
Last modified: October 1, 2014
This is version 52 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3