A4X9U2 (A4X9U2_SALTO) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Error-prone DNA polymerase HAMAP MF_01902
EC=2.7.7.7 HAMAP MF_01902

Gene names

Name:	dnaE2 HAMAP MF_01902
Ordered Locus Names:	Strop_3239

Organism

Salinispora tropica (strain ATCC BAA-916 / DSM 44818 / CNB-440) [Complete proteome] [HAMAP] EMBL ABP55673.1

Taxonomic identifier

369723 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Micromonosporineae › Micromonosporaceae › Salinispora

Protein attributes

Sequence length	1124 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase By similarity. HAMAP MF_01902
Catalytic activity	Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). HAMAP MF_01902 SAAS SAAS004013
Subcellular location	Cytoplasm By similarity HAMAP MF_01902 SAAS SAAS004013.
Sequence similarities	Belongs to the DNA polymerase type-C family. DnaE2 subfamily. HAMAP MF_01902

Ontologies

Keywords
Biological process	DNA damage DNA repair HAMAP MF_01902 SAAS SAAS004013 DNA replication HAMAP MF_01902 SAAS SAAS004013
Cellular component	Cytoplasm HAMAP MF_01902 SAAS SAAS023073
Molecular function	DNA-directed DNA polymerase HAMAP MF_01902 SAAS SAAS004013 Nucleotidyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	DNA repair Inferred from electronic annotation. Source: HAMAP DNA replication Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	3'-5' exonuclease activity Inferred from electronic annotation. Source: InterPro DNA binding Inferred from electronic annotation. Source: InterPro DNA-directed DNA polymerase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A4X9U2 [UniParc]. Last modified May 29, 2007. Version 1. Checksum: C01A2B67EFEEE9B8	FASTA	1,124	122,083
	10 20 30 40 50 60 MSFYNPDLPW SELERVLSGE STRGQRRTRD GQRHLHVVDP LAVEADGGDA PARAGRRPHH 70 80 90 100 110 120 PPPATARPDD VVPYAELHTH TNFSFLDGAS HPEELAEEAV RLGLTALAVT DHDGFYGVVR 130 140 150 160 170 180 FAEAARALHL PTVFGAELSL DLPGAPNGEP DPLGRHLLLL AHGHEGYARL AATISRAQLR 190 200 210 220 230 240 GGEKGRPIYG ELAEVAAELR DHVLVLTGCR KGHVPAALLT EGVDAAAREL DRLTALFGAE 250 260 270 280 290 300 TVAVELTDHG HPIDADRNDA LAELAEAAGL PTVATNNVHY ATPGRRRLAT TLAAVRARRS 310 320 330 340 350 360 LDEIDGWLPA AGAAHLRSGA EMAARFAAYP GAVARAAEFG AELAFDLQLV APALPAYPVA 370 380 390 400 410 420 SGHTEMSWLR HLTARGARER YGPPEAHPEA YAQLEHELNM IEELGFPGYF LVVYDIVTFC 430 440 450 460 470 480 REQDIYCQGR GSAANSAVCY ALRITNVDAV RHRLLFERFL APERDGPPDI DVDIESSRRE 490 500 510 520 530 540 EVIQHVYARY GREHTAQVAN VISYRPRSAV RDVAKAFGFS PGQQDAWSKQ IDRWGSVAAA 550 560 570 580 590 600 DVEGIPEPVV AYADAVQTFP RHLGIHSGGM VICDRPVIEV CPVEWGRMPG RSVLQWDKDD 610 620 630 640 650 660 CAAVGLVKFD LLGLGMLAAL HHGYDMIGAR LELGDMTLDD DEVYDMLCRA DAVGVFQVES 670 680 690 700 710 720 RAQMATLPRL KPRCFYDLVV EVALIRPGPI QGGSVHPYIR RKNGQEPVTF PHPLMRNALE 730 740 750 760 770 780 KTLGVPLFQE QLMQLAIDLA GFDAAEADQL RRAMGAKRSA ERMARIADRL YAGMAERGIT 790 800 810 820 830 840 GELADDVYRK LTAFASYGFP ESHAMSFAYL VYASSWLKRY HPAPFLAALL NAQPMGFYSP 850 860 870 880 890 900 QTLVDDARRH GVEVRRPDVN ASGAGAVLES TPSTRWGSQP GEPPHAWGLG GPAVRLGLDS 910 920 930 940 950 960 VRTLGGEVAG RIETERAARG PYRDMSDLAR RVGLTAAQLE ALATADAFAC FGVTRRQALW 970 980 990 1000 1010 1020 SAGAAAQEHP DRLPGTVPGT VAPTLPGMGA VDRLVADVWA TGLSPESHPA RFVREQLDAL 1030 1040 1050 1060 1070 1080 GAVPIARLAR VEPGRRVRVG GIVTHRQRPA TAGGVTFLNL EDETGMLNVT CSPGLWQRYR 1090 1100 1110 1120 QVAKNSGGLV VRGLLHRHEG VINFTADRLD PIELPVRPAA RDFR

References

[1]

"Complete sequence of Salinispora tropica CNB-440." Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Sun H., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Jensen P.R., Moore B.S., Udwary D.W., Richardson P. Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000667 Genomic DNA. Translation: ABP55673.1.
RefSeq	YP_001160051.1. NC_009380.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	A4X9U2.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5059704.
GenomeReviews	Gene locus Strop_3239 in contig CP000667_GR.
KEGG	stp:Strop_3239.
PATRIC	23445584. VBISalTro43511_3332.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0587.
HOGENOM	HBG734490.
OMA	EQPAIRL.
ProtClustDB	PRK05672.
Enzyme and pathway databases
BioCyc	STRO369723:STROP_3239-MONOMER.
Family and domain databases
HAMAP	MF_01902. DNApol_error_prone. [Tree]
InterPro	IPR011708. DNA_pol3_alpha. IPR023073. DNA_pol_error_prone. IPR004013. PHP_C. IPR003141. Pol/His_phosphatase_N. IPR016195. Pol/histidinol_Pase-like. IPR004805. PolC_alpha. [Graphical view]
KO	K14162.
Pfam	PF07733. DNA_pol3_alpha. 1 hit. PF02811. PHP. 1 hit. [Graphical view]
SMART	SM00481. POLIIIAc. 1 hit. [Graphical view]
SUPFAM	SSF89550. PHP-like. 1 hit.
TIGRFAMs	TIGR00594. Polc. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A4X9U2_SALTO

Accession

Primary (citable) accession number: A4X9U2

Entry history

Integrated into UniProtKB/TrEMBL:	May 29, 2007
Last sequence update:	May 29, 2007
Last modified:	December 14, 2011
This is version 35 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)