Skip Header

Contribute Send feedback
Read comments (?) or add your own

A4X9S3 (RSMH_SALTO) Reviewed, UniProtKB/Swiss-Prot

Last modified December 14, 2011. Version 41. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Ribosomal RNA small subunit methyltransferase H
EC=2.1.1.199
Alternative name(s):
16S rRNA m(4)C1402 methyltransferase
rRNA (cytosine-N(4)-)-methyltransferase RsmH
Gene names
Name:rsmH
Synonyms:mraW
Ordered Locus Names:Strop_3220
OrganismSalinispora tropica (strain ATCC BAA-916 / DSM 44818 / CNB-440) [Complete proteome] [HAMAP]
Taxonomic identifier369723 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Micromonosporineae › Micromonosporaceae › Salinispora

Protein attributes

Sequence length371 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA By similarity. HAMAP MF_01007

Catalytic activity

S-adenosyl-L-methionine + cytosine(1402) in 16S rRNA = S-adenosyl-L-homocysteine + N(4)-methylcytosine(1402) in 16S rRNA. HAMAP MF_01007

Subcellular location

Cytoplasm By similarity HAMAP MF_01007.

Sequence similarities

Belongs to the methyltransferase superfamily. RsmH family.

Ontologies

Keywords
   Biological processrRNA processing
   Cellular componentCytoplasm
   LigandS-adenosyl-L-methionine
   Molecular functionMethyltransferase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processrRNA processing

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionmethyltransferase activity

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 371371Ribosomal RNA small subunit methyltransferase H HAMAP MF_01007
PRO_0000387096

Regions

Region43 – 453S-adenosyl-L-methionine binding By similarity

Sites

Binding site621S-adenosyl-L-methionine By similarity
Binding site961S-adenosyl-L-methionine; via amide nitrogen By similarity
Binding site1101S-adenosyl-L-methionine By similarity
Binding site1171S-adenosyl-L-methionine By similarity

Sequences

Sequence LengthMass (Da)Tools
A4X9S3 [UniParc].

Last modified May 29, 2007. Version 1.
Checksum: F1ABC2B26F7FEDD6

FASTA37140,641
        10         20         30         40         50         60 
MGELRGAHVP VLLERCLELL SPALDRTGQT GRTVYVDATL GLGGHAEAIL TAHPRTMLVG 

        70         80         90        100        110        120 
LDRDTEALAH ARVRLARFAD RVHLEHAVYD ELPDVLDRIG HPVVDGILFD LGVSSLQLDA 

       130        140        150        160        170        180 
PDRGFAYAQD APLDMRMDQS RGVTAEEVVN SYSHPELARV LRVYGEEKFA SRIASAIVRE 

       190        200        210        220        230        240 
RDRAPITSSA QLAELVRQAI PAPARRTGGH PAKRTFQALR IEVNRELAAL ETALPAALDR 

       250        260        270        280        290        300 
LAIEGRMVVL SYHSLEDRLT KVALADRVRS KGPIDLPVEL PGTGPTFRLL SRGAELPGEA 

       310        320        330        340        350        360 
EVAVNPRAAS VRLRAAERLD PTQQQRQRTD RERYRRQVRA MHQPGTGSAV RRPVSGDDGT 

       370 
GTDEEGEGHD D

« Hide

References

[1]"Complete sequence of Salinispora tropica CNB-440."
Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Sun H., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Jensen P.R., Moore B.S., Udwary D.W., Richardson P.
Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC BAA-916 / DSM 44818 / CNB-440.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000667 Genomic DNA. Translation: ABP55654.1.
RefSeqYP_001160032.1. NC_009380.1.

3D structure databases

ProteinModelPortalA4X9S3.
ModBaseSearch...

Protein-protein interaction databases

STRINGA4X9S3.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5059685.
GenomeReviewsGene locus Strop_3220 in contig CP000667_GR.
KEGGstp:Strop_3220.
PATRIC23445544. VBISalTro43511_3312.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0275.
HOGENOMHBG302779.
OMANPATRAF.
ProtClustDBPRK00050.

Enzyme and pathway databases

BioCycSTRO369723:STROP_3220-MONOMER.

Family and domain databases

HAMAPMF_01007. 16SrRNA_methyltr_H.
[Tree]
InterProIPR002903. SAM-dep_MeTrfase_MraW.
IPR023397. SAM-dep_MeTrfase_MraW_recog.
[Graphical view]
Gene3DG3DSA:1.10.150.170. G3DSA:1.10.150.170. 1 hit.
KOK03438.
PANTHERPTHR11265. Bact_methyltrans. 1 hit.
PfamPF01795. Methyltransf_5. 1 hit.
[Graphical view]
PIRSFPIRSF004486. MraW. 1 hit.
SUPFAMSSF81799. SSF81799. 1 hit.
TIGRFAMsTIGR00006. TIGR00006. 1 hit.
ProtoNetSearch...

Entry information

Entry nameRSMH_SALTO
AccessionPrimary (citable) accession number: A4X9S3
Entry history
Integrated into UniProtKB/Swiss-Prot: November 3, 2009
Last sequence update: May 29, 2007
Last modified: December 14, 2011
This is version 41 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents