A4X9N2 (A4X9N2_SALTO) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Indole-3-glycerol phosphate synthase HAMAP MF_00134
Short name=IGPS HAMAP MF_00134
EC=4.1.1.48 HAMAP MF_00134

Gene names

Name:	trpC HAMAP MF_00134
Ordered Locus Names:	Strop_3172

Organism

Salinispora tropica (strain ATCC BAA-916 / DSM 44818 / CNB-440) [Complete proteome] [HAMAP] EMBL ABP55606.1

Taxonomic identifier

369723 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Micromonosporineae › Micromonosporaceae › Salinispora

Protein attributes

Sequence length	286 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate = 1-C-(3-indolyl)-glycerol 3-phosphate + CO2 + H2O. HAMAP MF_00134
Pathway	Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 4/5. HAMAP MF_00134
Sequence similarities	Belongs to the TrpC family. HAMAP MF_00134

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Aromatic amino acid biosynthesis Tryptophan biosynthesis HAMAP MF_00134
Molecular function	Decarboxylase HAMAP MF_00134 Lyase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	tryptophan biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular function	indole-3-glycerol-phosphate synthase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A4X9N2 [UniParc]. Last modified May 29, 2007. Version 1. Checksum: 1A3A1ED4D54EF521	FASTA	286	30,070
	10 20 30 40 50 60 MTAEHAHAEG SDAGSAKPSV LDEILAGVRE DVARRQEQVP LERIRELAAA APPPLDAYAA 70 80 90 100 110 120 LRRPGVAVVA EVKRSSPSKG QLAEIADPSD LASDYAAGGA RAISVLTEGR WFGGSLDDLA 130 140 150 160 170 180 AVRAAVDVPV LRKDFVVSSY QVHEARAHGA DLVLLIVAAL EQKVLVGLLE RIESLGMTAL 190 200 210 220 230 240 VEVHDEEEAD RALEAGAQVI GVNARDLRTL EVDRSVFERI APGLPSSVVK IAESGVRGPH 250 260 270 280 DLIRYASAGA DAVLVGEGLV TQKSPREAVA ELVNAGNHPA TPRPVR

References

[1]

"Complete sequence of Salinispora tropica CNB-440." Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Sun H., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Jensen P.R., Moore B.S., Udwary D.W., Richardson P. Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000667 Genomic DNA. Translation: ABP55606.1.
RefSeq	YP_001159984.1. NC_009380.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	A4X9N2.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5059637.
GenomeReviews	Gene locus Strop_3172 in contig CP000667_GR.
KEGG	stp:Strop_3172.
PATRIC	23445448. VBISalTro43511_3264.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0134.
HOGENOM	HBG540956.
OMA	LEYAVPH.
PhylomeDB	A4X9N2.
ProtClustDB	CLSK969551.
Enzyme and pathway databases
BioCyc	STRO369723:STROP_3172-MONOMER.
Family and domain databases
HAMAP	MF_00134_A. IGPS_A. [Tree] MF_00134_B. IGPS_B. [Tree]
InterPro	IPR013785. Aldolase_TIM. IPR013798. Indole-3-glycerol_P_synth. IPR001468. Indole-3-GlycerolPSynthase_CS. IPR011060. RibuloseP-bd_barrel. [Graphical view]
Gene3D	G3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
KO	K01609.
Pfam	PF00218. IGPS. 1 hit. [Graphical view]
SUPFAM	SSF51366. RibP_bind_barrel. 1 hit.
PROSITE	PS00614. IGPS. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A4X9N2_SALTO

Accession

Primary (citable) accession number: A4X9N2

Entry history

Integrated into UniProtKB/TrEMBL:	May 29, 2007
Last sequence update:	May 29, 2007
Last modified:	December 14, 2011
This is version 40 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)