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A4X9H1

- UVRC_SALTO

UniProt

A4X9H1 - UVRC_SALTO

Protein

UvrABC system protein C

Gene

uvrC

Organism
Salinispora tropica (strain ATCC BAA-916 / DSM 44818 / CNB-440)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 53 (01 Oct 2014)
      Sequence version 1 (29 May 2007)
      Previous versions | rss
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    Functioni

    The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.UniRule annotation

    GO - Molecular functioni

    1. DNA binding Source: UniProtKB-HAMAP
    2. excinuclease ABC activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. nucleotide-excision repair Source: UniProtKB-HAMAP
    2. SOS response Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Excision nuclease

    Keywords - Biological processi

    DNA damage, DNA excision, DNA repair, SOS response

    Enzyme and pathway databases

    BioCyciSTRO369723:GI49-3144-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    UvrABC system protein CUniRule annotation
    Short name:
    Protein UvrCUniRule annotation
    Alternative name(s):
    Excinuclease ABC subunit CUniRule annotation
    Gene namesi
    Name:uvrCUniRule annotation
    Ordered Locus Names:Strop_3109
    OrganismiSalinispora tropica (strain ATCC BAA-916 / DSM 44818 / CNB-440)
    Taxonomic identifieri369723 [NCBI]
    Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesMicromonosporineaeMicromonosporaceaeSalinispora
    ProteomesiUP000000235: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell
    2. excinuclease repair complex Source: InterPro

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 665665UvrABC system protein CPRO_1000077832Add
    BLAST

    Interactioni

    Subunit structurei

    Interacts with UvrB in an incision complex.UniRule annotation

    Protein-protein interaction databases

    STRINGi369723.Strop_3109.

    Structurei

    3D structure databases

    ProteinModelPortaliA4X9H1.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini16 – 9580GIY-YIGUniRule annotationAdd
    BLAST
    Domaini208 – 24336UVRUniRule annotationAdd
    BLAST

    Sequence similaritiesi

    Belongs to the UvrC family.UniRule annotation
    Contains 1 GIY-YIG domain.UniRule annotation
    Contains 1 UVR domain.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0322.
    HOGENOMiHOG000279962.
    KOiK03703.
    OMAiAMHEVIT.
    OrthoDBiEOG6K13R9.

    Family and domain databases

    Gene3Di3.40.1440.10. 1 hit.
    4.10.860.10. 1 hit.
    HAMAPiMF_00203. UvrC.
    InterProiIPR027299. GIY-YIG_dom.
    IPR000305. GIY-YIG_SF.
    IPR003583. Hlx-hairpin-Hlx_DNA-bd_motif.
    IPR010994. RuvA_2-like.
    IPR001943. UVR_dom.
    IPR004791. UvrC.
    IPR001162. UvrC_homol_region.
    [Graphical view]
    PfamiPF01541. GIY-YIG. 1 hit.
    PF02151. UVR. 1 hit.
    PF08459. UvrC_HhH_N. 1 hit.
    [Graphical view]
    SMARTiSM00465. GIYc. 1 hit.
    SM00278. HhH1. 2 hits.
    [Graphical view]
    SUPFAMiSSF46600. SSF46600. 1 hit.
    SSF47781. SSF47781. 1 hit.
    SSF82771. SSF82771. 1 hit.
    TIGRFAMsiTIGR00194. uvrC. 1 hit.
    PROSITEiPS50164. GIY_YIG. 1 hit.
    PS50151. UVR. 1 hit.
    PS50165. UVRC. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    A4X9H1-1 [UniParc]FASTAAdd to Basket

    « Hide

    MADPSSYRPA PGTIPESPGV YRFRDGTGRV IYVGKARNLR NRLNSYFADP    50
    VNLHQRTRQM VFTAESVDWI SVATEVEALQ QEFTEIKQYD PRFNVRYRDD 100
    KSYPYLAVTV SEEFPRLQVM RGAKRKGVRY FGPYSHAWAI RETLDLLLRV 150
    FPARTCSSGV FKRAGQVGRP CLLGYIDKCA APCVGSVSAE EHRAIVEGFC 200
    DFMAGRTDLM VRRLEREMAD ASAELEFERA ARLRDDLAAL RRAMEKQTVV 250
    FGDGTDADVV AFADDPLEAA VQVFHVRDGR IRGQRGWVVE KTEELTIGDL 300
    VHHFCTQVYG GEQGEADVPR ELLVPELPAD VEALADWLSD HRGSRVTLRV 350
    PQRGDKRALL ETVARNATDA LARHKLKRAG DLTTRSKALD EIAETLGLQT 400
    APLRIECYDI SQIQGTDVVA SMVVFEDGLP RKSEYRRFII RGATDDLSAM 450
    SEVLRRRFAR YLDARAETGE AGVESAGDPA TPAGPASTGP GVPDEPRVGT 500
    LVDPTTGRPR KFAYPPQLVV VDGGAPQVAA AAQALAELGV DDVALCGLAK 550
    RLEEVWLPDD DFPAILPRTS EGLYLLQRVR DEAHRFAITF HRQRRSRRMT 600
    ESALDRVPGL GEVRRKALLR HFGSLKRLSA ASVEEITEVP GVGQRTAEAI 650
    LAALGDSTQP DEPRT 665
    Length:665
    Mass (Da):73,708
    Last modified:May 29, 2007 - v1
    Checksum:i0002825DC6F4A3C8
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000667 Genomic DNA. Translation: ABP55545.1.
    RefSeqiYP_001159923.1. NC_009380.1.

    Genome annotation databases

    EnsemblBacteriaiABP55545; ABP55545; Strop_3109.
    GeneIDi5059573.
    KEGGistp:Strop_3109.
    PATRICi23445318. VBISalTro43511_3200.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000667 Genomic DNA. Translation: ABP55545.1 .
    RefSeqi YP_001159923.1. NC_009380.1.

    3D structure databases

    ProteinModelPortali A4X9H1.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 369723.Strop_3109.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABP55545 ; ABP55545 ; Strop_3109 .
    GeneIDi 5059573.
    KEGGi stp:Strop_3109.
    PATRICi 23445318. VBISalTro43511_3200.

    Phylogenomic databases

    eggNOGi COG0322.
    HOGENOMi HOG000279962.
    KOi K03703.
    OMAi AMHEVIT.
    OrthoDBi EOG6K13R9.

    Enzyme and pathway databases

    BioCyci STRO369723:GI49-3144-MONOMER.

    Family and domain databases

    Gene3Di 3.40.1440.10. 1 hit.
    4.10.860.10. 1 hit.
    HAMAPi MF_00203. UvrC.
    InterProi IPR027299. GIY-YIG_dom.
    IPR000305. GIY-YIG_SF.
    IPR003583. Hlx-hairpin-Hlx_DNA-bd_motif.
    IPR010994. RuvA_2-like.
    IPR001943. UVR_dom.
    IPR004791. UvrC.
    IPR001162. UvrC_homol_region.
    [Graphical view ]
    Pfami PF01541. GIY-YIG. 1 hit.
    PF02151. UVR. 1 hit.
    PF08459. UvrC_HhH_N. 1 hit.
    [Graphical view ]
    SMARTi SM00465. GIYc. 1 hit.
    SM00278. HhH1. 2 hits.
    [Graphical view ]
    SUPFAMi SSF46600. SSF46600. 1 hit.
    SSF47781. SSF47781. 1 hit.
    SSF82771. SSF82771. 1 hit.
    TIGRFAMsi TIGR00194. uvrC. 1 hit.
    PROSITEi PS50164. GIY_YIG. 1 hit.
    PS50151. UVR. 1 hit.
    PS50165. UVRC. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Complete sequence of Salinispora tropica CNB-440."
      Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Sun H., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Jensen P.R., Moore B.S., Udwary D.W., Richardson P.
      Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC BAA-916 / DSM 44818 / CNB-440.

    Entry informationi

    Entry nameiUVRC_SALTO
    AccessioniPrimary (citable) accession number: A4X9H1
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 20, 2008
    Last sequence update: May 29, 2007
    Last modified: October 1, 2014
    This is version 53 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3