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A4X9H1

- UVRC_SALTO

UniProt

A4X9H1 - UVRC_SALTO

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Protein
UvrABC system protein C
Gene
uvrC, Strop_3109
Organism
Salinispora tropica (strain ATCC BAA-916 / DSM 44818 / CNB-440)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision By similarity.UniRule annotation

GO - Molecular functioni

  1. DNA binding Source: UniProtKB-HAMAP
  2. excinuclease ABC activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. SOS response Source: UniProtKB-HAMAP
  2. nucleotide-excision repair Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Excision nuclease

Keywords - Biological processi

DNA damage, DNA excision, DNA repair, SOS response

Enzyme and pathway databases

BioCyciSTRO369723:GI49-3144-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
UvrABC system protein C
Short name:
Protein UvrC
Alternative name(s):
Excinuclease ABC subunit C
Gene namesi
Name:uvrC
Ordered Locus Names:Strop_3109
OrganismiSalinispora tropica (strain ATCC BAA-916 / DSM 44818 / CNB-440)
Taxonomic identifieri369723 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesMicromonosporineaeMicromonosporaceaeSalinispora
ProteomesiUP000000235: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
  2. excinuclease repair complex Source: InterPro
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 665665UvrABC system protein CUniRule annotation
PRO_1000077832Add
BLAST

Interactioni

Subunit structurei

Interacts with UvrB in an incision complex By similarity.

Protein-protein interaction databases

STRINGi369723.Strop_3109.

Structurei

3D structure databases

ProteinModelPortaliA4X9H1.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini16 – 9580GIY-YIG
Add
BLAST
Domaini208 – 24336UVR
Add
BLAST

Sequence similaritiesi

Belongs to the UvrC family.
Contains 1 GIY-YIG domain.
Contains 1 UVR domain.

Phylogenomic databases

eggNOGiCOG0322.
HOGENOMiHOG000279962.
KOiK03703.
OMAiAMHEVIT.
OrthoDBiEOG6K13R9.

Family and domain databases

Gene3Di3.40.1440.10. 1 hit.
4.10.860.10. 1 hit.
HAMAPiMF_00203. UvrC.
InterProiIPR027299. GIY-YIG_dom.
IPR000305. GIY-YIG_SF.
IPR003583. Hlx-hairpin-Hlx_DNA-bd_motif.
IPR010994. RuvA_2-like.
IPR001943. UVR_dom.
IPR004791. UvrC.
IPR001162. UvrC_homol_region.
[Graphical view]
PfamiPF01541. GIY-YIG. 1 hit.
PF02151. UVR. 1 hit.
PF08459. UvrC_HhH_N. 1 hit.
[Graphical view]
SMARTiSM00465. GIYc. 1 hit.
SM00278. HhH1. 2 hits.
[Graphical view]
SUPFAMiSSF46600. SSF46600. 1 hit.
SSF47781. SSF47781. 1 hit.
SSF82771. SSF82771. 1 hit.
TIGRFAMsiTIGR00194. uvrC. 1 hit.
PROSITEiPS50164. GIY_YIG. 1 hit.
PS50151. UVR. 1 hit.
PS50165. UVRC. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A4X9H1-1 [UniParc]FASTAAdd to Basket

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MADPSSYRPA PGTIPESPGV YRFRDGTGRV IYVGKARNLR NRLNSYFADP    50
VNLHQRTRQM VFTAESVDWI SVATEVEALQ QEFTEIKQYD PRFNVRYRDD 100
KSYPYLAVTV SEEFPRLQVM RGAKRKGVRY FGPYSHAWAI RETLDLLLRV 150
FPARTCSSGV FKRAGQVGRP CLLGYIDKCA APCVGSVSAE EHRAIVEGFC 200
DFMAGRTDLM VRRLEREMAD ASAELEFERA ARLRDDLAAL RRAMEKQTVV 250
FGDGTDADVV AFADDPLEAA VQVFHVRDGR IRGQRGWVVE KTEELTIGDL 300
VHHFCTQVYG GEQGEADVPR ELLVPELPAD VEALADWLSD HRGSRVTLRV 350
PQRGDKRALL ETVARNATDA LARHKLKRAG DLTTRSKALD EIAETLGLQT 400
APLRIECYDI SQIQGTDVVA SMVVFEDGLP RKSEYRRFII RGATDDLSAM 450
SEVLRRRFAR YLDARAETGE AGVESAGDPA TPAGPASTGP GVPDEPRVGT 500
LVDPTTGRPR KFAYPPQLVV VDGGAPQVAA AAQALAELGV DDVALCGLAK 550
RLEEVWLPDD DFPAILPRTS EGLYLLQRVR DEAHRFAITF HRQRRSRRMT 600
ESALDRVPGL GEVRRKALLR HFGSLKRLSA ASVEEITEVP GVGQRTAEAI 650
LAALGDSTQP DEPRT 665
Length:665
Mass (Da):73,708
Last modified:May 29, 2007 - v1
Checksum:i0002825DC6F4A3C8
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000667 Genomic DNA. Translation: ABP55545.1.
RefSeqiYP_001159923.1. NC_009380.1.

Genome annotation databases

EnsemblBacteriaiABP55545; ABP55545; Strop_3109.
GeneIDi5059573.
KEGGistp:Strop_3109.
PATRICi23445318. VBISalTro43511_3200.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000667 Genomic DNA. Translation: ABP55545.1 .
RefSeqi YP_001159923.1. NC_009380.1.

3D structure databases

ProteinModelPortali A4X9H1.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 369723.Strop_3109.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABP55545 ; ABP55545 ; Strop_3109 .
GeneIDi 5059573.
KEGGi stp:Strop_3109.
PATRICi 23445318. VBISalTro43511_3200.

Phylogenomic databases

eggNOGi COG0322.
HOGENOMi HOG000279962.
KOi K03703.
OMAi AMHEVIT.
OrthoDBi EOG6K13R9.

Enzyme and pathway databases

BioCyci STRO369723:GI49-3144-MONOMER.

Family and domain databases

Gene3Di 3.40.1440.10. 1 hit.
4.10.860.10. 1 hit.
HAMAPi MF_00203. UvrC.
InterProi IPR027299. GIY-YIG_dom.
IPR000305. GIY-YIG_SF.
IPR003583. Hlx-hairpin-Hlx_DNA-bd_motif.
IPR010994. RuvA_2-like.
IPR001943. UVR_dom.
IPR004791. UvrC.
IPR001162. UvrC_homol_region.
[Graphical view ]
Pfami PF01541. GIY-YIG. 1 hit.
PF02151. UVR. 1 hit.
PF08459. UvrC_HhH_N. 1 hit.
[Graphical view ]
SMARTi SM00465. GIYc. 1 hit.
SM00278. HhH1. 2 hits.
[Graphical view ]
SUPFAMi SSF46600. SSF46600. 1 hit.
SSF47781. SSF47781. 1 hit.
SSF82771. SSF82771. 1 hit.
TIGRFAMsi TIGR00194. uvrC. 1 hit.
PROSITEi PS50164. GIY_YIG. 1 hit.
PS50151. UVR. 1 hit.
PS50165. UVRC. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Complete sequence of Salinispora tropica CNB-440."
    Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Sun H., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Jensen P.R., Moore B.S., Udwary D.W., Richardson P.
    Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC BAA-916 / DSM 44818 / CNB-440.

Entry informationi

Entry nameiUVRC_SALTO
AccessioniPrimary (citable) accession number: A4X9H1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: May 29, 2007
Last modified: May 14, 2014
This is version 52 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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