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A4X621 (PYRF_SALTO) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 47. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Orotidine 5'-phosphate decarboxylase

EC=4.1.1.23
Alternative name(s):
OMP decarboxylase
Short name=OMPDCase
Short name=OMPdecase
Gene names
Name:pyrF
Ordered Locus Names:Strop_1859
OrganismSalinispora tropica (strain ATCC BAA-916 / DSM 44818 / CNB-440) [Complete proteome] [HAMAP]
Taxonomic identifier369723 [NCBI]
Taxonomic lineageBacteriaActinobacteriaActinobacteridaeActinomycetalesMicromonosporineaeMicromonosporaceaeSalinispora

Protein attributes

Sequence length278 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Ontologies

Keywords
   Biological processPyrimidine biosynthesis
   Molecular functionDecarboxylase
Lyase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_process'de novo' UMP biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-UniPathway

'de novo' pyrimidine nucleobase biosynthetic process

Inferred from electronic annotation. Source: InterPro

   Molecular_functionorotidine-5'-phosphate decarboxylase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 278278Orotidine 5'-phosphate decarboxylase HAMAP-Rule MF_01215
PRO_1000085578

Sites

Active site961Proton donor By similarity

Sequences

Sequence LengthMass (Da)Tools
A4X621 [UniParc].

Last modified May 29, 2007. Version 1.
Checksum: E27423115C5185CE

FASTA27828,347
        10         20         30         40         50         60 
MESFGARLHR VVGERGPLCV GIDPHPGLLE RWGLDDDVRG LERFAGTVVE ALGDRVAVVK 

        70         80         90        100        110        120 
PQSAFFERFG SRGVAVLEST IRQLRTAGSL VLLDVKRGDI GSTVAAYASA YLDPSSPLHV 

       130        140        150        160        170        180 
DAVTVSPYLG VGALAPMFEL AAAQGGGVFV LALTSNPEGA AVQRARTADG RTVAQLVIDE 

       190        200        210        220        230        240 
ISQLNAGARP LGSVGLVVGA TIGQTGHELA AVNGPLLAPG LGAQGASAAD LRVVFGSSLP 

       250        260        270 
AVLPTYSREV LAAGPDVVAL RGAADRVLAD CRAALTGS 

« Hide

References

[1]"Complete sequence of Salinispora tropica CNB-440."
Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Sun H., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Jensen P.R., Moore B.S., Udwary D.W., Richardson P.
Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC BAA-916 / DSM 44818 / CNB-440.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000667 Genomic DNA. Translation: ABP54321.1.
RefSeqYP_001158699.1. NC_009380.1.

3D structure databases

ProteinModelPortalA4X621.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING369723.Strop_1859.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABP54321; ABP54321; Strop_1859.
GeneID5058318.
KEGGstp:Strop_1859.
PATRIC23442722. VBISalTro43511_1907.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0284.
HOGENOMHOG000245748.
KOK01591.
OMAGSTMGAY.
OrthoDBEOG6DZF33.

Enzyme and pathway databases

BioCycSTRO369723:GI49-1889-MONOMER.
UniPathwayUPA00070; UER00120.

Family and domain databases

Gene3D3.20.20.70. 1 hit.
HAMAPMF_01215. OMPdecase_type2.
InterProIPR013785. Aldolase_TIM.
IPR018089. OMPdecase_AS.
IPR011995. OMPdecase_type-2.
IPR001754. OMPdeCOase_dom.
IPR011060. RibuloseP-bd_barrel.
[Graphical view]
PfamPF00215. OMPdecase. 1 hit.
[Graphical view]
SMARTSM00934. OMPdecase. 1 hit.
[Graphical view]
SUPFAMSSF51366. SSF51366. 1 hit.
TIGRFAMsTIGR02127. pyrF_sub2. 1 hit.
PROSITEPS00156. OMPDECASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePYRF_SALTO
AccessionPrimary (citable) accession number: A4X621
Entry history
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: May 29, 2007
Last modified: May 14, 2014
This is version 47 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways