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A4X607 (AROC_SALTO) Reviewed, UniProtKB/Swiss-Prot

Last modified December 14, 2011. Version 36. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Chorismate synthase
EC=4.2.3.5
Alternative name(s):
5-enolpyruvylshikimate-3-phosphate phospholyase
Gene names
Name:aroC
Ordered Locus Names:Strop_1845
OrganismSalinispora tropica (strain ATCC BAA-916 / DSM 44818 / CNB-440) [Complete proteome] [HAMAP]
Taxonomic identifier369723 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Micromonosporineae › Micromonosporaceae › Salinispora

Protein attributes

Sequence length392 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

5-O-(1-carboxyvinyl)-3-phosphoshikimate = chorismate + phosphate. HAMAP MF_00300

Cofactor

Reduced flavin By similarity. HAMAP MF_00300

Pathway

Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 7/7. HAMAP MF_00300

Subunit structure

Homotetramer By similarity. HAMAP MF_00300

Sequence similarities

Belongs to the chorismate synthase family.

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Aromatic amino acid biosynthesis
   Molecular functionLyase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processaromatic amino acid family biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular functionchorismate synthase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 392392Chorismate synthase HAMAP MF_00300
PRO_1000079008

Sequences

Sequence LengthMass (Da)Tools
A4X607 [UniParc].

Last modified May 29, 2007. Version 1.
Checksum: 37562700E9E3D7C7

FASTA39241,154
        10         20         30         40         50         60 
MLRWLTAGES HGPALVALLE GVPAGVEVTT EEIAGELARR RLGYGRGARM AFEQDEIEII 

        70         80         90        100        110        120 
GGLRHGVTLG SPVAIRVGNS EWPKWRTVMA PDPVDSTELA GQARNAPLTR PRPGHADLAG 

       130        140        150        160        170        180 
MQKYGHTDAR PILERASARE TAARVAVGTV AKALLRQALG IEVVSHVVEL GTVATKPGLR 

       190        200        210        220        230        240 
PSPADGDRID ADPLRCLDPE ASVRMVAEVD AAKKDADTLG GVVEVLAYGV PPGLGSHVQW 

       250        260        270        280        290        300 
DRKLDARLAT ALMSIQAIKG VEIGDGWQQA RSRGSVAHDE IIPTATGVRR VTDRAGGLEG 

       310        320        330        340        350        360 
GITTGEPLRV RAAMKPISSL NRALSTVDIT SGEPATAINQ RSDVCAVPAA GVVAEAMVAL 

       370        380        390 
VLAEAAVEKF GGDSVVEQRR NLAGYLDALV VR

« Hide

References

[1]"Complete sequence of Salinispora tropica CNB-440."
Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Sun H., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Jensen P.R., Moore B.S., Udwary D.W., Richardson P.
Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC BAA-916 / DSM 44818 / CNB-440.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000667 Genomic DNA. Translation: ABP54307.1.
RefSeqYP_001158685.1. NC_009380.1.

3D structure databases

ProteinModelPortalA4X607.
SMRA4X607. Positions 1-392.
ModBaseSearch...

Protein-protein interaction databases

STRINGA4X607.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5058304.
GenomeReviewsGene locus Strop_1845 in contig CP000667_GR.
KEGGstp:Strop_1845.
PATRIC23442694. VBISalTro43511_1893.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0082.
HOGENOMHBG292336.
OMAMLRWLTA.
ProtClustDBPRK05382.

Enzyme and pathway databases

BioCycSTRO369723:STROP_1845-MONOMER.

Family and domain databases

HAMAPMF_00300. Chorismate_synth.
[Tree]
InterProIPR000453. Chorismate_synth.
IPR020541. Chorismate_synthase_CS.
[Graphical view]
KOK01736.
PANTHERPTHR21085. Chorismate_synth. 1 hit.
PfamPF01264. Chorismate_synt. 1 hit.
[Graphical view]
PIRSFPIRSF001456. Chorismate_synth. 1 hit.
SUPFAMSSF103263. Chorismate_synth. 1 hit.
TIGRFAMsTIGR00033. AroC. 1 hit.
PROSITEPS00787. CHORISMATE_SYNTHASE_1. 1 hit.
PS00788. CHORISMATE_SYNTHASE_2. 1 hit.
PS00789. CHORISMATE_SYNTHASE_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameAROC_SALTO
AccessionPrimary (citable) accession number: A4X607
Entry history
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: May 29, 2007
Last modified: December 14, 2011
This is version 36 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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