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Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Salinispora tropica (strain ATCC BAA-916 / DSM 44818 / CNB-440)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei181 – 1811UniRule annotation
Active sitei618 – 6181UniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. carbon fixation Source: UniProtKB-HAMAP
  2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
  3. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationSAAS annotation

Keywords - Biological processi

Carbon dioxide fixationUniRule annotationSAAS annotation

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotation, PyruvateImported

Enzyme and pathway databases

BioCyciSTRO369723:GI49-897-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotationSAAS annotation (EC:4.1.1.31UniRule annotationSAAS annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotation
Ordered Locus Names:Strop_0883Imported
OrganismiSalinispora tropica (strain ATCC BAA-916 / DSM 44818 / CNB-440)Imported
Taxonomic identifieri369723 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesMicromonosporineaeMicromonosporaceaeSalinispora
ProteomesiUP000000235 Componenti: Chromosome

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi369723.Strop_0883.

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

eggNOGiCOG2352.
HOGENOMiHOG000238647.
KOiK01595.
OMAiFTSNWEL.
OrthoDBiEOG6TJ7T8.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A4X3B0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRIPAGRSGS SHVNRGPRGL RPVPAVTILG VGQRCPSYSR KERIVTDQHD
60 70 80 90 100
HDGPDAALRA DIRRLGTLLG QTLARQEGRP LLDLVEEIRA QVRTDAPAAA
110 120 130 140 150
QRLAGLDVAT GTRLARAFST YFHLANITEQ VHRARDLRRR RAVQGGWLDQ
160 170 180 190 200
TAKMIAERGV PAEEIAAAAR RLAIRPVFTA HPTEAARRSI LSKLRAIADE
210 220 230 240 250
LDTETTNAVL YGASDEGPAN RRLAELLDLM WQTDELRLDR PDPTDEARNA
260 270 280 290 300
IYYLRDLYAE AAPQVLDDLA DTLRTLGVET SPTARPLTFG TWIGGDRDGN
310 320 330 340 350
PFVTPTVTRE VLAIAHEHGL AATEKAMDQL INEVSVSRRL RGVSLDLSAS
360 370 380 390 400
LATDLDALPE VAPRFRRVNA EEPYRLKARC VKAKLANTRQ RLWQGTAHTP
410 420 430 440 450
GRDYRGSDEL IADLELLRAS LARNSGQLTA VGRIASTIRT VSAFGLHLAT
460 470 480 490 500
MDVREHAEKH HEVLTQLFGA VGEVSDYPAL SRLERTKLLA DELTGRRPLS
510 520 530 540 550
TLDTPLTESA RRTFDVFGTI REAQDRFGTE VIESYIISMT LGVDDVLAAV
560 570 580 590 600
VLAREAGLVD VHSSRARIGF VPLLETPAEL NAGGELLDEL LSLPAYRALV
610 620 630 640 650
TARGDVQEVM LGYSDSNKEA GITTSQWSIH RAQRALRDVA ARHGVQLRLF
660 670 680 690 700
HGRGGTVGRG GGPTHDAILA QPYGTLDGEI KVTEQGEVIS DKYTLPALAR
710 720 730 740 750
ENLELTVAAV LQSTLLHTAP RQPAEMLERW DATMDVVSAA AYRSYRDLVE
760 770 780 790 800
DPDLPAYFWA STPTELLGAL NIGSRPAKRP NTGAGLAGLR AIPWVFGWTQ
810 820 830 840 850
TRQIVPGWFG VGSGLAAARA AGHGDVLAEM HRSWHFFRTF LSNVEMMLTK
860 870 880 890 900
TDLTIARRYV ETLVPKKLHP IFHKIEQEYE LTRREVLAVT VSPDLLENAP
910 920 930 940 950
VLQRTLAVRD TYLEPLHHLQ VALLQQYRDS GAPGRAVVTA PGSRRAPSDG
960 970
TALERALLTT VNGIAAGMRN TG
Length:972
Mass (Da):106,526
Last modified:May 29, 2007 - v1
Checksum:iC1DFC27FFC56C9BB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000667 Genomic DNA. Translation: ABP53360.1.
RefSeqiWP_011904794.1. NC_009380.1.
YP_001157738.1. NC_009380.1.

Genome annotation databases

EnsemblBacteriaiABP53360; ABP53360; Strop_0883.
KEGGistp:Strop_0883.
PATRICi23440679. VBISalTro43511_0901.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000667 Genomic DNA. Translation: ABP53360.1.
RefSeqiWP_011904794.1. NC_009380.1.
YP_001157738.1. NC_009380.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi369723.Strop_0883.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABP53360; ABP53360; Strop_0883.
KEGGistp:Strop_0883.
PATRICi23440679. VBISalTro43511_0901.

Phylogenomic databases

eggNOGiCOG2352.
HOGENOMiHOG000238647.
KOiK01595.
OMAiFTSNWEL.
OrthoDBiEOG6TJ7T8.

Enzyme and pathway databases

BioCyciSTRO369723:GI49-897-MONOMER.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Complete sequence of Salinispora tropica CNB-440."
    Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Sun H., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Jensen P.R., Moore B.S., Udwary D.W., Richardson P.
    Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC BAA-916 / DSM 44818 / CNB-440Imported.

Entry informationi

Entry nameiA4X3B0_SALTO
AccessioniPrimary (citable) accession number: A4X3B0
Entry historyi
Integrated into UniProtKB/TrEMBL: May 29, 2007
Last sequence update: May 29, 2007
Last modified: April 29, 2015
This is version 60 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.