A4X342 (A4X342_SALTO) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Adenosine deaminase HAMAP MF_00540
EC=3.5.4.4 HAMAP MF_00540

Alternative name(s):
Adenosine aminohydrolase HAMAP MF_00540

Gene names

Name:	add HAMAP MF_00540
Ordered Locus Names:	Strop_0815

Organism

Salinispora tropica (strain ATCC BAA-916 / DSM 44818 / CNB-440) [Complete proteome] [HAMAP] EMBL ABP53292.1

Taxonomic identifier

369723 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Micromonosporineae › Micromonosporaceae › Salinispora

Protein attributes

Sequence length	364 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Adenosine + H2O = inosine + NH3. HAMAP MF_00540
Cofactor	Binds 1 zinc ion per subunit By similarity. HAMAP MF_00540
Sequence similarities	Belongs to the adenosine and AMP deaminases family. Adenosine deaminase subfamily. HAMAP MF_00540

Ontologies

Keywords
Biological process	Nucleotide metabolism HAMAP MF_00540
Ligand	Metal-binding HAMAP MF_00540 Zinc HAMAP MF_00540
Molecular function	Hydrolase HAMAP MF_00540 EMBL ABP53292.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	purine ribonucleoside monophosphate biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular function	adenosine deaminase activity Inferred from electronic annotation. Source: HAMAP zinc ion binding Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	210	1	Proton donor By similarity HAMAP MF_00540
	Metal binding	19	1	Zinc; catalytic By similarity HAMAP MF_00540
	Metal binding	21	1	Zinc; catalytic By similarity HAMAP MF_00540
	Metal binding	207	1	Zinc; catalytic By similarity HAMAP MF_00540
	Metal binding	297	1	Zinc; catalytic By similarity HAMAP MF_00540
	Binding site	21	1	Substrate By similarity HAMAP MF_00540
	Binding site	23	1	Substrate By similarity HAMAP MF_00540
	Binding site	180	1	Substrate; via amide nitrogen and carbonyl oxygen By similarity HAMAP MF_00540
	Site	231	1	Important for catalytic activity By similarity HAMAP MF_00540

Sequences

	Sequence		Length	Mass (Da)
	A4X342 [UniParc]. Last modified May 29, 2007. Version 1. Checksum: 1C31089FC6A23235	FASTA	364	39,648
	10 20 30 40 50 60 MVATIRYEDI VQAPKALLHD HLDGGLRPAT VVELAAEAGH ELPTTDPEAL GRWFVDAASS 70 80 90 100 110 120 GSLERYLETF AHTVQVMQTA SALRRVAREC ALDLAADGVV YAEVRFAPEL HLERGLTLDE 130 140 150 160 170 180 VVEAVIAGFA EGSTAAAAEG TPIRVGTLLT AMRHAARSQE IAELAVRHRD TGVVGFDIAG 190 200 210 220 230 240 AEAGFPPTRH LDAFEYLQRE NFHFTIHAGE AFGLPSIWQA IQWCGADRLG HGVRIVDDIT 250 260 270 280 290 300 PGPEPVLGRL AAYVRDKRIP LELCPSSNVQ TGAAPSIADH PIGLLRDLRF RVTVNTDNRL 310 320 330 340 350 360 MSGTSMSREM ALLVDAFGYG WREMQWLTIN AMKSAFIPFD QRLQIIDEVI KPAYGRLLAS AGQP

References

[1]

"Complete sequence of Salinispora tropica CNB-440." Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Sun H., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Jensen P.R., Moore B.S., Udwary D.W., Richardson P. Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000667 Genomic DNA. Translation: ABP53292.1.
RefSeq	YP_001157670.1. NC_009380.1.
3D structure databases
ProteinModelPortal	A4X342.
ModBase	Search...
Protein-protein interaction databases
STRING	A4X342.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5057258.
GenomeReviews	Gene locus Strop_0815 in contig CP000667_GR.
KEGG	stp:Strop_0815.
PATRIC	23440531. VBISalTro43511_0827.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1816.
HOGENOM	HBG630382.
OMA	PYYMAMN.
PhylomeDB	A4X342.
ProtClustDB	PRK09358.
Enzyme and pathway databases
BioCyc	STRO369723:STROP_0815-MONOMER.
Family and domain databases
HAMAP	MF_00540. A_deaminase. [Tree]
InterPro	IPR001365. A/AMP_deaminase_dom. IPR006330. A_deaminase. [Graphical view]
KO	K01488.
Pfam	PF00962. A_deaminase. 1 hit. [Graphical view]
TIGRFAMs	TIGR01430. Aden_deam. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A4X342_SALTO

Accession

Primary (citable) accession number: A4X342

Entry history

Integrated into UniProtKB/TrEMBL:	May 29, 2007
Last sequence update:	May 29, 2007
Last modified:	December 14, 2011
This is version 31 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)