ID   A4X329_SALTO            Unreviewed;       368 AA.
AC   A4X329;
DT   29-MAY-2007, integrated into UniProtKB/TrEMBL.
DT   29-MAY-2007, sequence version 1.
DT   27-MAR-2024, entry version 99.
DE   SubName: Full=Transcriptional regulator, LacI family {ECO:0000313|EMBL:ABP53279.1};
GN   OrderedLocusNames=Strop_0802 {ECO:0000313|EMBL:ABP53279.1};
OS   Salinispora tropica (strain ATCC BAA-916 / DSM 44818 / JCM 13857 / NBRC
OS   105044 / CNB-440).
OC   Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC   Micromonosporaceae; Salinispora.
OX   NCBI_TaxID=369723 {ECO:0000313|EMBL:ABP53279.1, ECO:0000313|Proteomes:UP000000235};
RN   [1] {ECO:0000313|Proteomes:UP000000235}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-916 / DSM 44818 / CNB-440
RC   {ECO:0000313|Proteomes:UP000000235};
RX   PubMed=17563368; DOI=10.1073/pnas.0700962104;
RA   Udwary D.W., Zeigler L., Asolkar R.N., Singan V., Lapidus A., Fenical W.,
RA   Jensen P.R., Moore B.S.;
RT   "Genome sequencing reveals complex secondary metabolome in the marine
RT   actinomycete Salinispora tropica.";
RL   Proc. Natl. Acad. Sci. U.S.A. 104:10376-10381(2007).
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DR   EMBL; CP000667; ABP53279.1; -; Genomic_DNA.
DR   RefSeq; WP_011904713.1; NC_009380.1.
DR   AlphaFoldDB; A4X329; -.
DR   STRING; 369723.Strop_0802; -.
DR   KEGG; stp:Strop_0802; -.
DR   PATRIC; fig|369723.5.peg.814; -.
DR   eggNOG; COG1609; Bacteria.
DR   HOGENOM; CLU_037628_6_4_11; -.
DR   Proteomes; UP000000235; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR   CDD; cd01392; HTH_LacI; 1.
DR   CDD; cd06292; PBP1_AglR_RafR-like; 1.
DR   Gene3D; 3.40.50.2300; -; 2.
DR   Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR   InterPro; IPR000843; HTH_LacI.
DR   InterPro; IPR046335; LacI/GalR-like_sensor.
DR   InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR   InterPro; IPR028082; Peripla_BP_I.
DR   PANTHER; PTHR30146:SF121; HTH-TYPE TRANSCRIPTIONAL REPRESSOR CYTR; 1.
DR   PANTHER; PTHR30146; LACI-RELATED TRANSCRIPTIONAL REPRESSOR; 1.
DR   Pfam; PF00356; LacI; 1.
DR   Pfam; PF13377; Peripla_BP_3; 1.
DR   SMART; SM00354; HTH_LACI; 1.
DR   SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR   SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR   PROSITE; PS00356; HTH_LACI_1; 1.
DR   PROSITE; PS50932; HTH_LACI_2; 1.
PE   4: Predicted;
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000235};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT   DOMAIN          3..54
FT                   /note="HTH lacI-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50932"
FT   REGION          336..368
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   368 AA;  39382 MW;  3056B050712EE150 CRC64;
     MRARLSDIAQ QAEVSEATVS RVLNDRPGVA PETRQAVLTA LDVLGYERPA RLRKRCAGLV
     GLVVPELDNP IFPAFAQIIE SALAPTGFTP VLCTQTPGGI REDEYVEMLL DRQVSGIVFV
     SGLHADTTAD HDRYRALIAR PLPVVMVNGY APNLRAPFIS CDDREAAELA VTHLVALGHR
     RIGLITGPDR FVPVQRKVAG YKAAMRYRTD VSDAELAELT ELSLFGVEGG EAAATRLLDR
     GVTGLVCGSD PMALGAIRAA RQRGLTVPRD ISVVGYDDSP LMAFTDPPLT TVRQPVAAMA
     IAAVRALVDE INGHAAPHSE YLFRPELVVR GSTAVAQTPD VDPGAPTPSP LAVSVQTPPS
     ARRDPARR
//