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A4X1X1 (A4X1X1_SALTO) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 43. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Glutamate 5-kinase HAMAP MF_00456
EC=2.7.2.11 HAMAP MF_00456
Alternative name(s):
Gamma-glutamyl kinase HAMAP MF_00456
Gene names
Name:proB HAMAP MF_00456
Ordered Locus Names:Strop_0386
OrganismSalinispora tropica (strain ATCC BAA-916 / DSM 44818 / CNB-440) [Complete proteome] [HAMAP] EMBL ABP52871.1
Taxonomic identifier369723 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Micromonosporineae › Micromonosporaceae › Salinispora

Protein attributes

Sequence length385 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5-oxoproline By similarity. HAMAP MF_00456 SAAS SAAS011529

Catalytic activity

ATP + L-glutamate = ADP + L-glutamate 5-phosphate. HAMAP MF_00456 SAAS SAAS011529

Pathway

Amino-acid biosynthesis; L-proline biosynthesis; L-glutamate 5-semialdehyde from L-glutamate: step 1/2. HAMAP MF_00456 SAAS SAAS011529

Subcellular location

Cytoplasm By similarity SAAS SAAS011529 HAMAP MF_00456.

Sequence similarities

Belongs to the glutamate 5-kinase family. HAMAP MF_00456

Contains 1 PUA domain. HAMAP MF_00456 SAAS SAAS011529

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Domain293 – 37179PUA By similarity HAMAP MF_00456

Sequences

Sequence LengthMass (Da)Tools
A4X1X1 [UniParc].

Last modified May 29, 2007. Version 1.
Checksum: 6A9B58D990CCBCC0

FASTA38540,285
        10         20         30         40         50         60 
MGTGPSVDQP TPQNGQVRDS VRAARRVVVK IGSSSLTTAD GGLDDGRVDA LVDTLGTLAA 

        70         80         90        100        110        120 
QGREVVLVSS GAIAAGLAPL GLTRRPRDLA TQQAAASVGQ GLLIRRYAAA FARHRRTVGQ 

       130        140        150        160        170        180 
VLLTVDDMTR RAHYRNAYRT LRKLLDLGAV PIVNENDTVA TEEIRFGDND RLAALVAALV 

       190        200        210        220        230        240 
DTDLLLLLSD VDALWTGDPT RPGSTRIAEV RDERDLSGVA IGGAGRAGVG TGGMVTKVEA 

       250        260        270        280        290        300 
ARIATGFGIP VILTSADQAA EALDGKPVGT FFHPSQRRPT ARLFWLAHAT SPRGRLQLDP 

       310        320        330        340        350        360 
GAVAAVVDRR KSLLPAGITA VRGAFTAGDP VDLVDTDGVP VARGLVNYDA VELPGLLGRS 

       370        380 
TAELATALGP AYEREVVHCD DLVLL

« Hide

References

[1]"Complete sequence of Salinispora tropica CNB-440."
Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Sun H., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Jensen P.R., Moore B.S., Udwary D.W., Richardson P.
Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000667 Genomic DNA. Translation: ABP52871.1.
RefSeqYP_001157249.1. NC_009380.1.

3D structure databases

ProteinModelPortalA4X1X1.
ModBaseSearch...

Protein-protein interaction databases

STRINGA4X1X1.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5056824.
GenomeReviewsGene locus Strop_0386 in contig CP000667_GR.
KEGGstp:Strop_0386.
PATRIC23439667. VBISalTro43511_0400.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0263.
HOGENOMHBG507643.
OMATFGDNDM.
PhylomeDBA4X1X1.
ProtClustDBPRK05429.

Enzyme and pathway databases

BioCycSTRO369723:STROP_0386-MONOMER.

Family and domain databases

HAMAPMF_00456. ProB.
[Tree]
InterProIPR001048. Asp/Glu/Uridylate_kinase.
IPR001057. Glu/AcGlu_kinase.
IPR011529. Glu_5kinase.
IPR005715. Glu_5kinase/COase_Synthase.
IPR019797. Glutamate_5-kinase_CS.
IPR002478. PUA.
IPR015947. PUA-like_domain.
[Graphical view]
Gene3DG3DSA:3.40.1160.10. Aa_kinase. 1 hit.
KOK00931.
PfamPF00696. AA_kinase. 1 hit.
PF01472. PUA. 1 hit.
[Graphical view]
PIRSFPIRSF000729. GK. 1 hit.
PRINTSPR00474. GLU5KINASE.
SMARTSM00359. PUA. 1 hit.
[Graphical view]
SUPFAMSSF53633. Aa_kinase. 1 hit.
SSF88697. PUA-like. 1 hit.
TIGRFAMsTIGR01027. ProB. 1 hit.
PROSITEPS00902. GLUTAMATE_5_KINASE. 1 hit.
PS50890. PUA. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA4X1X1_SALTO
AccessionPrimary (citable) accession number: A4X1X1
Entry history
Integrated into UniProtKB/TrEMBL: May 29, 2007
Last sequence update: May 29, 2007
Last modified: December 14, 2011
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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