A4X1U4 (A4X1U4_SALTO) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Porphobilinogen synthase EMBL ABP52844.1
EC=4.2.1.24 EMBL ABP52844.1

Gene names

Ordered Locus Names:

Strop_0359

Organism

Salinispora tropica (strain ATCC BAA-916 / DSM 44818 / CNB-440) [Complete proteome] [HAMAP] EMBL ABP52844.1

Taxonomic identifier

369723 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Micromonosporineae › Micromonosporaceae › Salinispora

Protein attributes

Sequence length	327 AA.
Sequence status	Complete.
Protein existence	Predicted

Ontologies

Keywords
Ligand	Magnesium PIRSR PIRSR001415-5 Metal-binding PIRSR PIRSR001415-5
Molecular function	Lyase EMBL ABP52844.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	porphyrin-containing compound biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW porphobilinogen synthase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	197	1	Schiff-base intermediate with substrate By similarity PIRSR PIRSR001415-1
	Active site	249	1	Schiff-base intermediate with substrate By similarity PIRSR PIRSR001415-1
	Metal binding	234	1	Magnesium By similarity PIRSR PIRSR001415-5
	Binding site	207	1	Substrate 1 By similarity PIRSR PIRSR001415-2
	Binding site	218	1	Substrate 1 By similarity PIRSR PIRSR001415-2
	Binding site	275	1	Substrate 2 By similarity PIRSR PIRSR001415-2
	Binding site	314	1	Substrate 2 By similarity PIRSR PIRSR001415-2

Sequences

	Sequence		Length	Mass (Da)
	A4X1U4 [UniParc]. Last modified May 29, 2007. Version 1. Checksum: CF92427BFFC0F96C	FASTA	327	34,772
	10 20 30 40 50 60 MSYPEIRPRR LRRSPALRRL VAENRVDPAE LVLPMFVKEG LTEPRSVPSL PGVLQHSRES 70 80 90 100 110 120 LRKAAVAAVR AGVGGIMLFG VPADRDELGS GGANPNGILN AAIRDVVSEV GDATVVMSDL 130 140 150 160 170 180 CLDEFTSHGH CGVLASDGSV ANDATLAAYA EMAVAQAAAG VHVVGPSGMM DGQVGVVRRA 190 200 210 220 230 240 LDAAGHQDVS ILAYTAKYAS AFFGPFRDAV ESTLDGDRRT YQQDPANLRE SLREVALDVA 250 260 270 280 290 300 EGADMVMVKP ALPYLDVVAA VRSAVDVPVA AYQVSGEYAM VEAAAANGWI DREQAMLETL 310 320 TSIRRAGAQI ILTYWAVEAA QLLRQRY

References

[1]

"Complete sequence of Salinispora tropica CNB-440." Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Sun H., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Jensen P.R., Moore B.S., Udwary D.W., Richardson P. Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000667 Genomic DNA. Translation: ABP52844.1.
RefSeq	YP_001157222.1. NC_009380.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	A4X1U4.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5056797.
GenomeReviews	Gene locus Strop_0359 in contig CP000667_GR.
KEGG	stp:Strop_0359.
PATRIC	23439607. VBISalTro43511_0370.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0113.
HOGENOM	HBG285270.
OMA	FTSHGHD.
PhylomeDB	A4X1U4.
ProtClustDB	PRK09283.
Enzyme and pathway databases
BioCyc	STRO369723:STROP_0359-MONOMER.
Family and domain databases
InterPro	IPR013785. Aldolase_TIM. IPR001731. Porphobilinogen_synth. [Graphical view]
Gene3D	G3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
KO	K01698.
PANTHER	PTHR11458. AlaD_dehydratase. 1 hit.
Pfam	PF00490. ALAD. 1 hit. [Graphical view]
PIRSF	PIRSF001415. Porphbilin_synth. 1 hit.
PRINTS	PR00144. DALDHYDRTASE.
SMART	SM01004. ALAD. 1 hit. [Graphical view]
PROSITE	PS00169. D_ALA_DEHYDRATASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A4X1U4_SALTO

Accession

Primary (citable) accession number: A4X1U4

Entry history

Integrated into UniProtKB/TrEMBL:	May 29, 2007
Last sequence update:	May 29, 2007
Last modified:	January 25, 2012
This is version 34 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)