ID   A4X140_SALTO            Unreviewed;       314 AA.
AC   A4X140;
DT   29-MAY-2007, integrated into UniProtKB/TrEMBL.
DT   29-MAY-2007, sequence version 1.
DT   27-MAR-2024, entry version 73.
DE   SubName: Full=Type II site-specific deoxyribonuclease {ECO:0000313|EMBL:ABP52590.1};
DE            EC=3.1.21.4 {ECO:0000313|EMBL:ABP52590.1};
GN   OrderedLocusNames=Strop_0105 {ECO:0000313|EMBL:ABP52590.1};
OS   Salinispora tropica (strain ATCC BAA-916 / DSM 44818 / JCM 13857 / NBRC
OS   105044 / CNB-440).
OC   Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC   Micromonosporaceae; Salinispora.
OX   NCBI_TaxID=369723 {ECO:0000313|EMBL:ABP52590.1, ECO:0000313|Proteomes:UP000000235};
RN   [1] {ECO:0000313|Proteomes:UP000000235}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-916 / DSM 44818 / CNB-440
RC   {ECO:0000313|Proteomes:UP000000235};
RX   PubMed=17563368; DOI=10.1073/pnas.0700962104;
RA   Udwary D.W., Zeigler L., Asolkar R.N., Singan V., Lapidus A., Fenical W.,
RA   Jensen P.R., Moore B.S.;
RT   "Genome sequencing reveals complex secondary metabolome in the marine
RT   actinomycete Salinispora tropica.";
RL   Proc. Natl. Acad. Sci. U.S.A. 104:10376-10381(2007).
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DR   EMBL; CP000667; ABP52590.1; -; Genomic_DNA.
DR   RefSeq; WP_011904027.1; NC_009380.1.
DR   AlphaFoldDB; A4X140; -.
DR   STRING; 369723.Strop_0105; -.
DR   REBASE; 15127; StrCORF104P.
DR   KEGG; stp:Strop_0105; -.
DR   eggNOG; COG0827; Bacteria.
DR   HOGENOM; CLU_074525_0_0_11; -.
DR   Proteomes; UP000000235; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR   GO; GO:0009036; F:type II site-specific deoxyribonuclease activity; IEA:UniProtKB-EC.
DR   GO; GO:0009307; P:DNA restriction-modification system; IEA:InterPro.
DR   Gene3D; 3.40.1350.80; -; 1.
DR   Gene3D; 1.10.10.1820; BsuBI/PstI restriction endonuclease-like; 1.
DR   InterPro; IPR041963; BsuBI/PstI_C_sf.
DR   InterPro; IPR041454; BsuBI/PstI_N.
DR   InterPro; IPR041962; BsuBI/PstI_N_sf.
DR   InterPro; IPR009528; Restrct_endonuc_II_BsuBI_C.
DR   Pfam; PF06616; BsuBI_PstI_RE; 1.
DR   Pfam; PF17728; BsuBI_PstI_RE_N; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000313|EMBL:ABP52590.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000235}.
FT   DOMAIN          5..142
FT                   /note="BsuBI/PstI restriction endonuclease HTH"
FT                   /evidence="ECO:0000259|Pfam:PF17728"
FT   DOMAIN          154..307
FT                   /note="BsuBI/PstI restriction endonuclease"
FT                   /evidence="ECO:0000259|Pfam:PF06616"
SQ   SEQUENCE   314 AA;  35281 MW;  3E947A3DD3E4D1FA CRC64;
     MSVVRKIEEA SQILTALGMD AERSNERSAQ TLLALLHLKS DDTWADSANP MLGTRAIMDW
     IRDEYGRSYA ANTRETIRRF TLHQFADAFL IQQNPDQPTR PVNSPKWNYQ VTSEALTVVK
     AFGTPDFDSV LSEYLTRKPG LKAQYATARA RNRIPVTLPG GKPFTLSPGG QNVLIKQVVE
     EFCPQFTPGA EVLYVGDADA KWALFEAERL AEFGVSIDQH GKMPDLVVYL PDKDWIVLVE
     AASSHGPVDA KRHGELAALF KGATPGLVYI SCFPDRREMR KYLHRIAWET EVWCAEDPTH
     LIHFNGERFL GPYS
//