A4WZQ4 (F16A2_RHOS5) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Fructose-1,6-bisphosphatase class 1 2
Short name=FBPase class 1 2
EC=3.1.3.11

Alternative name(s):
D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 2

Gene names

Name:	fbp2
Ordered Locus Names:	Rsph17025_4015

Encoded on

Plasmid pRSPA02

Organism

Rhodobacter sphaeroides (strain ATCC 17025 / ATH 2.4.3) [Complete proteome] [HAMAP]

Taxonomic identifier

349102 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhodobacterales › Rhodobacteraceae › Rhodobacter

Protein attributes

Sequence length	331 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	D-fructose 1,6-bisphosphate + H2O = D-fructose 6-phosphate + phosphate. HAMAP MF_01855
Cofactor	Binds 2 magnesium ions per subunit By similarity. HAMAP MF_01855
Pathway	Carbohydrate biosynthesis; Calvin cycle. HAMAP MF_01855
Subunit structure	Homotetramer By similarity. HAMAP MF_01855
Subcellular location	Cytoplasm Potential HAMAP MF_01855.
Sequence similarities	Belongs to the FBPase class 1 family.

Ontologies

Keywords
Biological process	Calvin cycle Carbohydrate metabolism
Cellular component	Cytoplasm
Ligand	Magnesium Metal-binding
Molecular function	Hydrolase
Technical term	Complete proteome Plasmid
Gene Ontology (GO)
Biological process	reductive pentose-phosphate cycle Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	fructose 1,6-bisphosphate 1-phosphatase activity Inferred from electronic annotation. Source: EC metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 331	331	Fructose-1,6-bisphosphatase class 1 2 HAMAP MF_01855		PRO_0000364669
Regions
	Region	101 – 104	4	Substrate binding By similarity
Sites
	Metal binding	80	1	Magnesium 1 By similarity
	Metal binding	98	1	Magnesium 1 By similarity
	Metal binding	98	1	Magnesium 2 By similarity
	Metal binding	100	1	Magnesium 1; via carbonyl oxygen By similarity
	Metal binding	101	1	Magnesium 2 By similarity
	Metal binding	261	1	Magnesium 2 By similarity
	Binding site	189	1	Substrate By similarity

Sequences

	Sequence		Length	Mass (Da)
	A4WZQ4 [UniParc]. Last modified May 29, 2007. Version 1. Checksum: 8A17249AA2F99A7A	FASTA	331	35,314
	10 20 30 40 50 60 MTIELEDLGL TPELADVMQR LARVGGQIAR LISRNGLETD LAAGVGTNAG GDGQKALDVI 70 80 90 100 110 120 ADNAFRAALA GSAVAHYASE EQDEVVTLGE GALALAIDPL DGSSNIDVNV SIGTIFSIFP 130 140 150 160 170 180 AAESPEASFL RLGTEQIAAG YIIYGPQCAL VCSFGRGVHH WVLDLDAGIF RRMADIRPLP 190 200 210 220 230 240 AETSEFAINA SNYRHWPKPV RAFIDDLMAG ADGPRGKNFN MRWIASLVAE THRILMRGGV 250 260 270 280 290 300 FLYPGDDRKG YERGRLRHVY ECAPIAFLIT QAGGGASDGC DPILTALPDR LHARTPFVFG 310 320 330 CAGKVACVAA YHDLPGQETS ALFGTRGLFR S

References

[1]

"Complete sequence of plasmid pRSPA02 of Rhodobacter sphaeroides ATCC 17025." US DOE Joint Genome Institute Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chertkov O., Brettin T., Bruce D., Han C., Schmutz J., Larimer F., Land M. , Hauser L., Kyrpides N., Kim E., Richardson P., Mackenzie C., Choudhary M., Donohue T.J., Kaplan S. Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 17025 / ATH 2.4.3.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000663 Genomic DNA. Translation: ABP72868.1.
RefSeq	YP_001170173.1. NC_009430.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	A4WZQ4.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5086189.
GenomeReviews	Gene locus Rsph17025_4015 in contig CP000663_GR.
KEGG	rsq:Rsph17025_4015.
PATRIC	23166550. VBIRhoSph94549_4157.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0158.
HOGENOM	HBG731261.
OMA	WNADING.
ProtClustDB	CLSK841466.
Enzyme and pathway databases
BioCyc	RSPH349102:RSPH17025_4015-MONOMER.
Family and domain databases
HAMAP	MF_01855. FBPase_class1. [Tree]
InterPro	IPR000146. FBPase_class-1/SBPase. IPR020548. Fructose_bisphosphatase_AS. [Graphical view]
KO	K03841.
PANTHER	PTHR11556. In_FB_phphtase. 1 hit.
Pfam	PF00316. FBPase. 1 hit. [Graphical view]
PIRSF	PIRSF000904. FBPtase_SBPase. 1 hit.
PRINTS	PR00115. F16BPHPHTASE.
PROSITE	PS00124. FBPASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

F16A2_RHOS5

Accession

Primary (citable) accession number: A4WZQ4

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 3, 2009
Last sequence update:	May 29, 2007
Last modified:	January 25, 2012
This is version 41 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program