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Protein

tRNA pseudouridine synthase B

Gene

truB

Organism
Rhodobacter sphaeroides (strain ATCC 17025 / ATH 2.4.3)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.UniRule annotation

Catalytic activityi

tRNA uridine(55) = tRNA pseudouridine(55).UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei47 – 471NucleophileUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

tRNA processing

Enzyme and pathway databases

BioCyciRSPH349102:GHE1-4249-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
tRNA pseudouridine synthase BUniRule annotation (EC:5.4.99.25UniRule annotation)
Alternative name(s):
tRNA pseudouridine(55) synthaseUniRule annotation
Short name:
Psi55 synthaseUniRule annotation
tRNA pseudouridylate synthaseUniRule annotation
tRNA-uridine isomeraseUniRule annotation
Gene namesi
Name:truBUniRule annotation
Ordered Locus Names:Rsph17025_2922
OrganismiRhodobacter sphaeroides (strain ATCC 17025 / ATH 2.4.3)
Taxonomic identifieri349102 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhodobacteralesRhodobacteraceaeRhodobacter
Proteomesi
  • UP000000234 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 301301tRNA pseudouridine synthase BPRO_1000084657Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi349102.Rsph17025_2922.

Structurei

3D structure databases

ProteinModelPortaliA4WWP4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105D0T. Bacteria.
COG0130. LUCA.
HOGENOMiHOG000231225.
KOiK03177.
OMAiYELQFIR.
OrthoDBiEOG6358D3.

Family and domain databases

HAMAPiMF_01080. TruB_bact.
InterProiIPR020103. PsdUridine_synth_cat_dom.
IPR002501. PsdUridine_synth_N.
IPR014780. tRNA_psdUridine_synth_TruB.
IPR032819. TruB_C.
[Graphical view]
PANTHERiPTHR13767. PTHR13767. 1 hit.
PfamiPF16198. TruB_C_2. 1 hit.
PF01509. TruB_N. 1 hit.
[Graphical view]
SUPFAMiSSF55120. SSF55120. 1 hit.
TIGRFAMsiTIGR00431. TruB. 1 hit.

Sequencei

Sequence statusi: Complete.

A4WWP4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGRTRKGRAI SGWLVVDKPA GMTSTAVVNK VRWALGAQKA GHAGTLDPDA
60 70 80 90 100
TGVLAVALGE ATKTVPYITD ALKCYRFMVR LGVGTRTDDA SGEVIATSEA
110 120 130 140 150
RPEDPEIEAA LAAFRGEIMQ VPPQFSAVKV EGERAYDLAR EGERLDLAAR
160 170 180 190 200
PLWVESLELI SRPDADHVEL EMVCGKGGYV RSIARDLGQA LGCHGHVEWL
210 220 230 240 250
RRTWSGPFEA EDGISVATID ELAKSEELLA HVMPLACGLA DLPELPATAE
260 270 280 290 300
GAARLKCGNP GMVIASDVEF GEEAWASFQG QPVAVGIYKA GELHPTRVFN

L
Length:301
Mass (Da):32,158
Last modified:May 29, 2007 - v1
Checksum:i770BEAB31956233C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000661 Genomic DNA. Translation: ABP71808.1.
RefSeqiWP_011909867.1. NC_009428.1.

Genome annotation databases

EnsemblBacteriaiABP71808; ABP71808; Rsph17025_2922.
KEGGirsq:Rsph17025_2922.
PATRICi23164233. VBIRhoSph94549_3020.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000661 Genomic DNA. Translation: ABP71808.1.
RefSeqiWP_011909867.1. NC_009428.1.

3D structure databases

ProteinModelPortaliA4WWP4.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi349102.Rsph17025_2922.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABP71808; ABP71808; Rsph17025_2922.
KEGGirsq:Rsph17025_2922.
PATRICi23164233. VBIRhoSph94549_3020.

Phylogenomic databases

eggNOGiENOG4105D0T. Bacteria.
COG0130. LUCA.
HOGENOMiHOG000231225.
KOiK03177.
OMAiYELQFIR.
OrthoDBiEOG6358D3.

Enzyme and pathway databases

BioCyciRSPH349102:GHE1-4249-MONOMER.

Family and domain databases

HAMAPiMF_01080. TruB_bact.
InterProiIPR020103. PsdUridine_synth_cat_dom.
IPR002501. PsdUridine_synth_N.
IPR014780. tRNA_psdUridine_synth_TruB.
IPR032819. TruB_C.
[Graphical view]
PANTHERiPTHR13767. PTHR13767. 1 hit.
PfamiPF16198. TruB_C_2. 1 hit.
PF01509. TruB_N. 1 hit.
[Graphical view]
SUPFAMiSSF55120. SSF55120. 1 hit.
TIGRFAMsiTIGR00431. TruB. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 17025 / ATH 2.4.3.

Entry informationi

Entry nameiTRUB_RHOS5
AccessioniPrimary (citable) accession number: A4WWP4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: May 29, 2007
Last modified: January 20, 2016
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.