Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Elongation factor Tu

Gene

tuf1

more
Organism
Rhodobacter sphaeroides (strain ATCC 17025 / ATH 2.4.3)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi19 – 268GTPUniRule annotation
Nucleotide bindingi76 – 805GTPUniRule annotation
Nucleotide bindingi131 – 1344GTPUniRule annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Elongation factor

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

GTP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciRSPH349102:GHE1-3863-MONOMER.
RSPH349102:GHE1-3876-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Elongation factor TuUniRule annotation
Short name:
EF-TuUniRule annotation
Gene namesi
Name:tuf1UniRule annotation
Ordered Locus Names:Rsph17025_2536
AND
Name:tuf2UniRule annotation
Ordered Locus Names:Rsph17025_2549
OrganismiRhodobacter sphaeroides (strain ATCC 17025 / ATH 2.4.3)
Taxonomic identifieri349102 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhodobacteralesRhodobacteraceaeRhodobacter
ProteomesiUP000000234 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 391391Elongation factor TuPRO_0000337490Add
BLAST

Proteomic databases

PRIDEiA4WVL0.

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi349102.Rsph17025_2549.

Structurei

3D structure databases

ProteinModelPortaliA4WVL0.
SMRiA4WVL0. Positions 2-391.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini10 – 201192tr-type GAdd
BLAST

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni19 – 268G1By similarity
Regioni55 – 595G2By similarity
Regioni76 – 794G3By similarity
Regioni131 – 1344G4By similarity
Regioni169 – 1713G5By similarity

Sequence similaritiesi

Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.UniRule annotation

Phylogenomic databases

eggNOGiCOG0050.
HOGENOMiHOG000229290.
KOiK02358.
OMAiDEGGRHN.
OrthoDBiEOG6R5C6X.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
HAMAPiMF_00118_B. EF_Tu_B.
InterProiIPR031157. G_TR_CS.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR000795. TF_GTP-bd_dom.
IPR009000. Transl_B-barrel.
IPR009001. Transl_elong_EF1A/Init_IF2_C.
IPR004161. Transl_elong_EFTu/EF1A_2.
IPR004541. Transl_elong_EFTu/EF1A_bac/org.
IPR004160. Transl_elong_EFTu/EF1A_C.
[Graphical view]
PfamiPF03144. GTP_EFTU_D2. 1 hit.
PF03143. GTP_EFTU_D3. 1 hit.
[Graphical view]
PRINTSiPR00315. ELONGATNFCT.
SUPFAMiSSF50447. SSF50447. 1 hit.
SSF50465. SSF50465. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00485. EF-Tu. 1 hit.
TIGR00231. small_GTP. 1 hit.
PROSITEiPS00301. G_TR_1. 1 hit.
PS51722. G_TR_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A4WVL0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAKAKFERNK PHVNIGTIGH VDHGKTTLTA AITKYFGEFR AYDQIDGAPE
60 70 80 90 100
ERARGITIST AHVEYESESR HYAHVDCPGH ADYVKNMITG AAQMDGAILV
110 120 130 140 150
VNAADGPMPQ TREHILLGRQ VGIPYMVVYM NKVDQVDDPE LLELVEMEIR
160 170 180 190 200
ELLSSYDYPG DDIPIIKGSA LAAMNGTDKE IGEDSIRALI AAVDEYIPTP
210 220 230 240 250
ARAVDQPFLM PVEDVFSISG RGTVATGRIE RGVVKVGEEL EIVGIRPSKK
260 270 280 290 300
TVCTGVEMFR KLLDQGEAGD NVGLLLRGVD RDGIERGQVL CKPGSVKPHT
310 320 330 340 350
KFEAEAYILT KEEGGRHTPF FANYRPQFYF RTTDVTGTVE LPEGTEMVMP
360 370 380 390
GDNLKFNVEL IAPIAMEEKL RFAIREGGRT VGAGVVSKII A
Length:391
Mass (Da):42,875
Last modified:May 29, 2007 - v1
Checksum:i1163373768E7DE42
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000661 Genomic DNA. Translation: ABP71424.1.
CP000661 Genomic DNA. Translation: ABP71437.1.
RefSeqiWP_011909488.1. NC_009428.1.
YP_001168729.1. NC_009428.1.
YP_001168742.1. NC_009428.1.

Genome annotation databases

EnsemblBacteriaiABP71424; ABP71424; Rsph17025_2536.
ABP71437; ABP71437; Rsph17025_2549.
KEGGirsq:Rsph17025_2536.
rsq:Rsph17025_2549.
PATRICi23163409. VBIRhoSph94549_2620.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000661 Genomic DNA. Translation: ABP71424.1.
CP000661 Genomic DNA. Translation: ABP71437.1.
RefSeqiWP_011909488.1. NC_009428.1.
YP_001168729.1. NC_009428.1.
YP_001168742.1. NC_009428.1.

3D structure databases

ProteinModelPortaliA4WVL0.
SMRiA4WVL0. Positions 2-391.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi349102.Rsph17025_2549.

Proteomic databases

PRIDEiA4WVL0.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABP71424; ABP71424; Rsph17025_2536.
ABP71437; ABP71437; Rsph17025_2549.
KEGGirsq:Rsph17025_2536.
rsq:Rsph17025_2549.
PATRICi23163409. VBIRhoSph94549_2620.

Phylogenomic databases

eggNOGiCOG0050.
HOGENOMiHOG000229290.
KOiK02358.
OMAiDEGGRHN.
OrthoDBiEOG6R5C6X.

Enzyme and pathway databases

BioCyciRSPH349102:GHE1-3863-MONOMER.
RSPH349102:GHE1-3876-MONOMER.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
HAMAPiMF_00118_B. EF_Tu_B.
InterProiIPR031157. G_TR_CS.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR000795. TF_GTP-bd_dom.
IPR009000. Transl_B-barrel.
IPR009001. Transl_elong_EF1A/Init_IF2_C.
IPR004161. Transl_elong_EFTu/EF1A_2.
IPR004541. Transl_elong_EFTu/EF1A_bac/org.
IPR004160. Transl_elong_EFTu/EF1A_C.
[Graphical view]
PfamiPF03144. GTP_EFTU_D2. 1 hit.
PF03143. GTP_EFTU_D3. 1 hit.
[Graphical view]
PRINTSiPR00315. ELONGATNFCT.
SUPFAMiSSF50447. SSF50447. 1 hit.
SSF50465. SSF50465. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00485. EF-Tu. 1 hit.
TIGR00231. small_GTP. 1 hit.
PROSITEiPS00301. G_TR_1. 1 hit.
PS51722. G_TR_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 17025 / ATH 2.4.3.

Entry informationi

Entry nameiEFTU_RHOS5
AccessioniPrimary (citable) accession number: A4WVL0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: May 29, 2007
Last modified: June 24, 2015
This is version 61 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.