A4WUY5 (A4WUY5_RHOS5) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Choline dehydrogenase RuleBase RU003969
EC=1.1.99.1 RuleBase RU003969

Gene names

Ordered Locus Names:

Rsph17025_2310

Organism

Rhodobacter sphaeroides (strain ATCC 17025 / ATH 2.4.3) [Complete proteome] [HAMAP]

Taxonomic identifier

349102 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhodobacterales › Rhodobacteraceae › Rhodobacter

Protein attributes

Sequence length	548 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine By similarity. SAAS SAAS007867
Catalytic activity	Choline + acceptor = betaine aldehyde + reduced acceptor. RuleBase RU003969 SAAS SAAS007867
Cofactor	FAD By similarity. SAAS SAAS007867 RuleBase RU003968
Pathway	Amine and polyamine biosynthesis; betaine biosynthesis via choline pathway; betaine aldehyde from choline (cytochrome c reductase route): step 1/1. RuleBase RU003969 SAAS SAAS007867
Sequence similarities	Belongs to the GMC oxidoreductase family. RuleBase RU003968

Ontologies

Keywords
Ligand	FAD SAAS SAAS011533 Flavoprotein SAAS SAAS011533 RuleBase RU003968
Molecular function	Oxidoreductase SAAS SAAS007867
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glycine betaine biosynthetic process from choline Inferred from electronic annotation. Source: InterPro
Molecular function	choline dehydrogenase activity Inferred from electronic annotation. Source: EC flavin adenine dinucleotide binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A4WUY5 [UniParc]. Last modified May 29, 2007. Version 1. Checksum: 399ED8E542D0FA58	FASTA	548	60,002
	10 20 30 40 50 60 MFDYVIVGAG SAGCAMAYRL GEAGRSVLVI EHGGTDAGPF IQMPAALSYP MNMGIYDWGL 70 80 90 100 110 120 KTEPEPHLGG RVLATPRGKV IGGSSSINGM VYVRGHARDF DHWAEAGAAG WGFAEVLPYF 130 140 150 160 170 180 KRMENWHVPG DVDWRGHDGP LHVTRGPRSN PLFNAFIEAG RQAGYPVTDD YNGAAQEGFG 190 200 210 220 230 240 PMEATIWQGR RWSAANAYLK PAMKRFGVKV TRALALRVVI EEGRAVGVEV QRRGRREVIR 250 260 270 280 290 300 AGREVILAAS SINTPKLLML SGIGPAAHLA EHGLPVVADR PGVGRNLQDH LEVYMQYASL 310 320 330 340 350 360 LPVTLFKHWN LRGKVMVGAQ WLFTGRGLGA SNQFEACAFI RSRPGVDYPD IQYHFLPIAV 370 380 390 400 410 420 RYDGKAAAEG HGFQVHVGPM RSPSRGSVTL RSADPEAAPV IRFNYMSTPE DWEDFRRCIR 430 440 450 460 470 480 LTREIFGQEA FRPFVKGEIQ PGPACQSDDE IDAFIREHVE SAYHPCGTAR MGRADDPMAV 490 500 510 520 530 540 VDPECRVIGV AGLRVADSSI FPRVTNGNLN APSMMVGEKA ADHVLGRTPL APLNHEPVVN PNWRVAQR

References

[1]

"Complete sequence of chromosome of Rhodobacter sphaeroides ATCC 17025." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chertkov O., Brettin T., Bruce D., Han C., Schmutz J., Larimer F., Land M. , Hauser L., Kyrpides N., Kim E., Richardson P., Mackenzie C., Choudhary M., Donohue T.J., Kaplan S. Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 17025 / ATH 2.4.3.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000661 Genomic DNA. Translation: ABP71199.1.
RefSeq	YP_001168504.1. NC_009428.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	A4WUY5.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5084960.
GenomeReviews	Gene locus Rsph17025_2310 in contig CP000661_GR.
KEGG	rsq:Rsph17025_2310.
PATRIC	23162937. VBIRhoSph94549_2384.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG2303.
HOGENOM	HBG734713.
OMA	GPFIQMP.
PhylomeDB	A4WUY5.
ProtClustDB	PRK02106.
Enzyme and pathway databases
BioCyc	RSPH349102:RSPH17025_2310-MONOMER.
Family and domain databases
InterPro	IPR011533. Choline_dehydrogenase. IPR012132. GMC_OxRdtase. IPR000172. GMC_OxRdtase_N. IPR007867. GMC_OxRtase_C. [Graphical view]
KO	K00108.
Pfam	PF05199. GMC_oxred_C. 1 hit. PF00732. GMC_oxred_N. 1 hit. [Graphical view]
PIRSF	PIRSF000137. Alcohol_oxidase. 1 hit.
TIGRFAMs	TIGR01810. BetA. 1 hit.
PROSITE	PS00623. GMC_OXRED_1. 1 hit. PS00624. GMC_OXRED_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A4WUY5_RHOS5

Accession

Primary (citable) accession number: A4WUY5

Entry history

Integrated into UniProtKB/TrEMBL:	May 29, 2007
Last sequence update:	May 29, 2007
Last modified:	December 14, 2011
This is version 38 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)