A4WR71 (URED_RHOS5) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Urease accessory protein UreD

Gene names

Name:	ureD
Ordered Locus Names:	Rsph17025_0984

Organism

Rhodobacter sphaeroides (strain ATCC 17025 / ATH 2.4.3) [Complete proteome] [HAMAP]

Taxonomic identifier

349102 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhodobacterales › Rhodobacteraceae › Rhodobacter

Protein attributes

Sequence length	275 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter By similarity. HAMAP MF_01384
Subunit structure	UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel By similarity.
Subcellular location	Cytoplasm By similarity HAMAP MF_01384.
Sequence similarities	Belongs to the UreD family.

Ontologies

Keywords
Biological process	Nickel insertion
Cellular component	Cytoplasm
Molecular function	Chaperone
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	nitrogen compound metabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	nickel cation binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 275	275	Urease accessory protein UreD HAMAP MF_01384		PRO_0000340506

Sequences

	Sequence		Length	Mass (Da)
	A4WR71 [UniParc]. Last modified May 29, 2007. Version 1. Checksum: 8496B5C953C875C0	FASTA	275	28,940
	10 20 30 40 50 60 MNALTPPRDC LERSQGHAQV TLARVLGAVR LRDLAQRGSA KAFLPRVDGP VPEIVFLNTS 70 80 90 100 110 120 GGLTGGDRLS YRLEVGEGCR AVATTQTAER AYAAGRGVAQ VRVAHEVGAG GWLDWLPQET 130 140 150 160 170 180 ILFEDSALDR RTEIVLGPGA GCLMVESVVL GRAAMGETLS RLAFRDLRQI TRGGRPVLVE 190 200 210 220 230 240 PLALDDRALA AAAGAAVLGG LRALATLALV GPGAEDALGP ARAVLDEPGV EAAASAFDGK 250 260 270 LLVRMLALDG WPLRRQVARV LGVLRGRALP RVWQD

References

[1]

"Complete sequence of chromosome of Rhodobacter sphaeroides ATCC 17025." US DOE Joint Genome Institute Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chertkov O., Brettin T., Bruce D., Han C., Schmutz J., Larimer F., Land M. , Hauser L., Kyrpides N., Kim E., Richardson P., Mackenzie C., Choudhary M., Donohue T.J., Kaplan S. Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 17025 / ATH 2.4.3.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000661 Genomic DNA. Translation: ABP69885.1.
RefSeq	YP_001167190.1. NC_009428.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	A4WR71.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5083200.
GenomeReviews	Gene locus Rsph17025_0984 in contig CP000661_GR.
KEGG	rsq:Rsph17025_0984.
PATRIC	23160149. VBIRhoSph94549_1008.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0829.
HOGENOM	HBG711156.
OMA	QETILFD.
ProtClustDB	CLSK940836.
Enzyme and pathway databases
BioCyc	RSPH349102:RSPH17025_0984-MONOMER.
Family and domain databases
HAMAP	MF_01384. UreD. [Tree]
InterPro	IPR002669. UreD. [Graphical view]
KO	K03190.
Pfam	PF01774. UreD. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

URED_RHOS5

Accession

Primary (citable) accession number: A4WR71

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 10, 2008
Last sequence update:	May 29, 2007
Last modified:	January 25, 2012
This is version 29 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program