A4WQ91 (GLMM_RHOS5) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Phosphoglucosamine mutase
EC=5.4.2.10

Gene names

Name:	glmM
Ordered Locus Names:	Rsph17025_0649

Organism

Rhodobacter sphaeroides (strain ATCC 17025 / ATH 2.4.3) [Complete proteome] [HAMAP]

Taxonomic identifier

349102 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhodobacterales › Rhodobacteraceae › Rhodobacter

Protein attributes

Sequence length	447 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate By similarity. HAMAP MF_01554_B
Catalytic activity	Alpha-D-glucosamine 1-phosphate = D-glucosamine 6-phosphate. HAMAP MF_01554_B
Cofactor	Binds 1 magnesium ion per subunit By similarity. HAMAP MF_01554_B
Post-translational modification	Activated by phosphorylation By similarity. HAMAP MF_01554_B
Sequence similarities	Belongs to the phosphohexose mutase family.

Ontologies

Keywords
Ligand	Magnesium Metal-binding
Molecular function	Isomerase
PTM	Phosphoprotein
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	magnesium ion binding Inferred from electronic annotation. Source: InterPro phosphoglucosamine mutase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 447	447	Phosphoglucosamine mutase HAMAP MF_01554_B		PRO_1000068913
Sites
	Active site	103	1	Phosphoserine intermediate By similarity
	Metal binding	103	1	Magnesium; via phosphate group By similarity
	Metal binding	242	1	Magnesium By similarity
	Metal binding	244	1	Magnesium By similarity
	Metal binding	246	1	Magnesium By similarity
Amino acid modifications
	Modified residue	103	1	Phosphoserine By similarity

Sequences

	Sequence		Length	Mass (Da)
	A4WQ91 [UniParc]. Last modified May 29, 2007. Version 1. Checksum: 5BFAE861E86C0E44	FASTA	447	47,718
	10 20 30 40 50 60 MTRKLFGTDG VRGRANSYPM TAEVALRLGA AAGRYFRPVG AGSPRVVIGK DTRLSGYMLE 70 80 90 100 110 120 NALTAGLTST GMNVLLLGPV PTPAVGFLTR SMRADLGVMI SASHNPHEDN GIKFFGPDGF 130 140 150 160 170 180 KLSDEAEAEI EAILAGEIQP AQPGNIGRAK RIDDGRGRYQ EYCKTTFPAG LRLDGLKVVI 190 200 210 220 230 240 DCANGAAYRA APEVLWELGA EVIPLGVEPD GKNINLRCGS THPEAAAEAV RAHGADVGIC 250 260 270 280 290 300 LDGDADRVII LDEQGRQADG DQIMALFAAR WAEEGRLRDA TLVATVMSNL GLERFLSARG 310 320 330 340 350 360 LRLERTPVGD RYVVEAMRRG GWNLGGEQSG HIVMTDFATT GDGLLAGLQF LAAMAQTGRK 370 380 390 400 410 420 ASELSRSFET VPQLLQNVRY AAGQEPLTAP SVQAVIREAE VRLNGSGRLL IRKSGTEPLI 430 440 RVMAECEDEA LLRDVVEEIV AAVKDAA

References

[1]

"Complete sequence of chromosome of Rhodobacter sphaeroides ATCC 17025." US DOE Joint Genome Institute Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S., Chertkov O., Brettin T., Bruce D., Han C., Schmutz J., Larimer F., Land M. , Hauser L., Kyrpides N., Kim E., Richardson P., Mackenzie C., Choudhary M., Donohue T.J., Kaplan S. Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 17025 / ATH 2.4.3.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000661 Genomic DNA. Translation: ABP69555.1.
RefSeq	YP_001166860.1. NC_009428.1.
3D structure databases
ProteinModelPortal	A4WQ91.
ModBase	Search...
Protein-protein interaction databases
STRING	A4WQ91.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	5082993.
GenomeReviews	Gene locus Rsph17025_0649 in contig CP000661_GR.
KEGG	rsq:Rsph17025_0649.
PATRIC	23159441. VBIRhoSph94549_0659.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1109.
HOGENOM	HBG644964.
OMA	IGSAKRI.
PhylomeDB	A4WQ91.
ProtClustDB	PRK14315.
Enzyme and pathway databases
BioCyc	RSPH349102:RSPH17025_0649-MONOMER.
Family and domain databases
HAMAP	MF_01554_B. GlmM_B. [Tree]
InterPro	IPR005844. A-D-PHexomutase_a/b/a-I. IPR016055. A-D-PHexomutase_a/b/a-I/II/III. IPR005845. A-D-PHexomutase_a/b/a-II. IPR005846. A-D-PHexomutase_a/b/a-III. IPR005843. A-D-PHexomutase_C. IPR016066. A-D-PHexomutase_CS. IPR005841. Alpha-D-phosphohexomutase_SF. IPR006352. GlmM. [Graphical view]
Gene3D	G3DSA:3.40.120.10. A-D-PHexomutase_a/b/a-I/II/III. 3 hits.
KO	K03431.
Pfam	PF02878. PGM_PMM_I. 1 hit. PF02879. PGM_PMM_II. 1 hit. PF02880. PGM_PMM_III. 1 hit. PF00408. PGM_PMM_IV. 1 hit. [Graphical view]
PRINTS	PR00509. PGMPMM.
SUPFAM	SSF53738. A-D-PHexomutase_a/b/a-I/II/III. 3 hits.
TIGRFAMs	TIGR01455. GlmM. 1 hit.
PROSITE	PS00710. PGM_PMM. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GLMM_RHOS5

Accession

Primary (citable) accession number: A4WQ91

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 5, 2008
Last sequence update:	May 29, 2007
Last modified:	January 25, 2012
This is version 36 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program