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Protein

tRNA pseudouridine synthase A

Gene

truA

Organism
Rhodobacter sphaeroides (strain ATCC 17025 / ATH 2.4.3)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.UniRule annotation

Catalytic activityi

tRNA uridine(38-40) = tRNA pseudouridine(38-40).UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei52NucleophileUniRule annotation1
Binding sitei111SubstrateUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomerase
Biological processtRNA processing

Enzyme and pathway databases

BioCyciRSPH349102:G1G8M-518-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
tRNA pseudouridine synthase AUniRule annotation (EC:5.4.99.12UniRule annotation)
Alternative name(s):
tRNA pseudouridine(38-40) synthaseUniRule annotation
tRNA pseudouridylate synthase IUniRule annotation
tRNA-uridine isomerase IUniRule annotation
Gene namesi
Name:truAUniRule annotation
Ordered Locus Names:Rsph17025_0502
OrganismiRhodobacter sphaeroides (strain ATCC 17025 / ATH 2.4.3)
Taxonomic identifieri349102 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhodobacteralesRhodobacteraceaeRhodobacter
Proteomesi
  • UP000000234 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000171551 – 257tRNA pseudouridine synthase AAdd BLAST257

Proteomic databases

PRIDEiA4WPU4

Interactioni

Subunit structurei

Homodimer.UniRule annotation

Protein-protein interaction databases

STRINGi349102.Rsph17025_0502

Structurei

3D structure databases

ProteinModelPortaliA4WPU4
SMRiA4WPU4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the tRNA pseudouridine synthase TruA family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105DI7 Bacteria
COG0101 LUCA
HOGENOMiHOG000248674
KOiK06173
OMAiFLYGMVR
OrthoDBiPOG091H010Q

Family and domain databases

Gene3Di3.30.70.660, 1 hit
HAMAPiMF_00171 TruA, 1 hit
InterProiView protein in InterPro
IPR020103 PsdUridine_synth_cat_dom_sf
IPR001406 PsdUridine_synth_TruA
IPR020097 PsdUridine_synth_TruA_a/b_dom
IPR020095 PsdUridine_synth_TruA_C
PANTHERiPTHR11142 PTHR11142, 1 hit
PfamiView protein in Pfam
PF01416 PseudoU_synth_1, 2 hits
PIRSFiPIRSF001430 tRNA_psdUrid_synth, 1 hit
SUPFAMiSSF55120 SSF55120, 1 hit
TIGRFAMsiTIGR00071 hisT_truA, 1 hit

Sequencei

Sequence statusi: Complete.

A4WPU4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPRYALKIEY DGAPFAGWQR QAVLPSVQGA IEAALGRLEP GPHTIAAAGR
60 70 80 90 100
TDTGVHATGQ VAHCDLGKDW DPFRLAGALN AHLKPLPVAV VAAARVGEDF
110 120 130 140 150
HARFSAIERR YLFRLLARRA PEVHDRGRVW RVPHPLDGAA MREAAAHLVG
160 170 180 190 200
RHDFTTFRAI GCQAASPVKT LDELTLETVE VPNGVEYRFR LRARSFLHNQ
210 220 230 240 250
VRSIVGTLER VGAGAWAPDR VKEALEARDR AACGPVCPPQ GLYLTGVGYP

ADPFAAT
Length:257
Mass (Da):27,915
Last modified:May 29, 2007 - v1
Checksum:i919CC4274A470066
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000661 Genomic DNA Translation: ABP69408.1
RefSeqiWP_011907558.1, NC_009428.1

Genome annotation databases

EnsemblBacteriaiABP69408; ABP69408; Rsph17025_0502
KEGGirsq:Rsph17025_0502

Similar proteinsi

Entry informationi

Entry nameiTRUA_RHOS5
AccessioniPrimary (citable) accession number: A4WPU4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: May 29, 2007
Last modified: May 23, 2018
This is version 70 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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