A4WMK4 (DCD_PYRAR) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable deoxycytidine triphosphate deaminase
Short name=dCTP deaminase
EC=3.5.4.13

Gene names

Name:	dcd
Ordered Locus Names:	Pars_2075

Organism

Pyrobaculum arsenaticum (strain DSM 13514 / JCM 11321) [Complete proteome] [HAMAP]

Taxonomic identifier

340102 [NCBI]

Taxonomic lineage

cellular organisms › Archaea › Crenarchaeota › Thermoprotei › Thermoproteales › Thermoproteaceae › Pyrobaculum › Pyrobaculum arsenaticum

Protein attributes

Sequence length	176 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	dCTP + H2O = dUTP + NH3. HAMAP-Rule MF_00146
Pathway	Pyrimidine metabolism; dUMP biosynthesis; dUMP from dCTP (dUTP route): step 1/2. HAMAP-Rule MF_00146
Sequence similarities	Belongs to the dCTP deaminase family.

Ontologies

Keywords
Biological process	Nucleotide metabolism
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	dUMP biosynthetic process Inferred from electronic annotation. Source: UniProtKB-UniPathway dUTP biosynthetic process Inferred from electronic annotation. Source: InterPro pyrimidine ribonucleotide biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular_function	dCTP deaminase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 176	176	Probable deoxycytidine triphosphate deaminase HAMAP-Rule MF_00146		PRO_1000117987

Sequences

	Sequence		Length	Mass (Da)
	A4WMK4 [UniParc]. Last modified May 29, 2007. Version 1. Checksum: B8AEC64072F7A883	FASTA	176	19,537
	10 20 30 40 50 60 MILANDELKR LISTGRLKVD PLYPDTVREN GLDLRIGGEY AIYAYESTVV RPCDLETAKP 70 80 90 100 110 120 LFRIVKSDEV VIPPRNFVLL TTEEYVKMPD DVVGFANLRS TLARYGLVIP PTIVDAGFEG 130 140 150 160 170 NITIEVVNES PNTIVLKRGM RFLHLVLAKA EGRAQYSGLY QGQRGVTPPK GLKGEC

References

[1]

"Complete sequence of Pyrobaculum arsenaticum DSM 13514." US DOE Joint Genome Institute Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N. , Cozen A.E., Fitz-Gibbon S.T., House C.H., Saltikov C., Lowe T.M., Richardson P. Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: DSM 13514 / JCM 11321.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000660 Genomic DNA. Translation: ABP51621.1.
RefSeq	YP_001154273.1. NC_009376.1.
3D structure databases
ProteinModelPortal	A4WMK4.
ModBase	Search...
Protein-protein interaction databases
STRING	340102.Pars_2075.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ABP51621; ABP51621; Pars_2075.
GeneID	5054646.
KEGG	pas:Pars_2075.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0717.
HOGENOM	HOG000228601.
KO	K01494.
OMA	GSFAWVD.
ProtClustDB	PRK00416.
Enzyme and pathway databases
BioCyc	PARS340102:GHGQ-2107-MONOMER.
UniPathway	UPA00610; UER00665.
Family and domain databases
HAMAP	MF_00146. dCTP_deaminase.
InterPro	IPR011962. dCTP_deam. IPR008180. dUTP_pyroPase. [Graphical view]
Pfam	PF00692. dUTPase. 1 hit. [Graphical view]
TIGRFAMs	TIGR02274. dCTP_deam. 1 hit.
ProtoNet	Search...

Entry information

Entry name

DCD_PYRAR

Accession

Primary (citable) accession number: A4WMK4

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 14, 2009
Last sequence update:	May 29, 2007
Last modified:	May 29, 2013
This is version 46 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program