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Protein

Nucleoside-triphosphatase THEP1

Gene

Pars_1717

Organism
Pyrobaculum arsenaticum (strain DSM 13514 / JCM 11321)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency.UniRule annotation

Catalytic activityi

NTP + H2O = NDP + phosphate.UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi15 – 228ATPUniRule annotation
Nucleotide bindingi101 – 1088ATPUniRule annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciPARS340102:GHGQ-1739-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Nucleoside-triphosphatase THEP1UniRule annotation (EC:3.6.1.15UniRule annotation)
Short name:
NTPase THEP1UniRule annotation
Alternative name(s):
Nucleoside triphosphate phosphohydrolaseUniRule annotation
Gene namesi
Ordered Locus Names:Pars_1717
OrganismiPyrobaculum arsenaticum (strain DSM 13514 / JCM 11321)
Taxonomic identifieri340102 [NCBI]
Taxonomic lineageiArchaeaCrenarchaeotaThermoproteiThermoprotealesThermoproteaceaePyrobaculum
Proteomesi
  • UP000001567 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 172172Nucleoside-triphosphatase THEP1PRO_0000360025Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliA4WLK1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the THEP1 NTPase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000006446.
KOiK06928.
OMAiYYWLTPE.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
HAMAPiMF_00796. NTPase_1. 1 hit.
InterProiIPR003593. AAA+_ATPase.
IPR004948. Nuc-triphosphatase_THEP1.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamiPF03266. NTPase_1. 1 hit.
[Graphical view]
SMARTiSM00382. AAA. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.

Sequencei

Sequence statusi: Complete.

A4WLK1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MMWRERAEVR IGISGMPGVG KTTLVLKVAE LAAKKLRVCG FVTQEVRERG
60 70 80 90 100
VRIGFDVVDI ASGRRTPLAR VGTGEPSVGK YVVFLGACST ISEALRGTCD
110 120 130 140 150
LLIVDEIGAM EFKCPGFGSD LERAVYNSPK VLAVVHRNYT NLAESLGFEI
160 170
LWLTRDNWST IYNQVVHRLG LA
Length:172
Mass (Da):18,886
Last modified:May 29, 2007 - v1
Checksum:i4AB75991C6456CFA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000660 Genomic DNA. Translation: ABP51268.1.

Genome annotation databases

EnsemblBacteriaiABP51268; ABP51268; Pars_1717.
KEGGipas:Pars_1717.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000660 Genomic DNA. Translation: ABP51268.1.

3D structure databases

ProteinModelPortaliA4WLK1.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABP51268; ABP51268; Pars_1717.
KEGGipas:Pars_1717.

Phylogenomic databases

HOGENOMiHOG000006446.
KOiK06928.
OMAiYYWLTPE.

Enzyme and pathway databases

BioCyciPARS340102:GHGQ-1739-MONOMER.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
HAMAPiMF_00796. NTPase_1. 1 hit.
InterProiIPR003593. AAA+_ATPase.
IPR004948. Nuc-triphosphatase_THEP1.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamiPF03266. NTPase_1. 1 hit.
[Graphical view]
SMARTiSM00382. AAA. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiNTPTH_PYRAR
AccessioniPrimary (citable) accession number: A4WLK1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 20, 2009
Last sequence update: May 29, 2007
Last modified: December 9, 2015
This is version 56 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.