Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

A4WKR8 (A4WKR8_PYRAR) Unreviewed, UniProtKB/TrEMBL

Last modified April 16, 2014. Version 47. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein attributes

Sequence length185 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + thymidine = ADP + thymidine 5'-phosphate. HAMAP-Rule MF_00124

Subunit structure

Homotetramer By similarity. HAMAP-Rule MF_00124

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00124.

Sequence similarities

Belongs to the thymidine kinase family. HAMAP-Rule MF_00124

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Nucleotide binding7 – 148ATP By similarity HAMAP-Rule MF_00124
Nucleotide binding83 – 864ATP By similarity HAMAP-Rule MF_00124

Sites

Active site841Proton acceptor By similarity HAMAP-Rule MF_00124
Metal binding1391Zinc By similarity HAMAP-Rule MF_00124
Metal binding1421Zinc By similarity HAMAP-Rule MF_00124
Metal binding1771Zinc By similarity HAMAP-Rule MF_00124
Metal binding1801Zinc By similarity HAMAP-Rule MF_00124

Sequences

Sequence LengthMass (Da)Tools
A4WKR8 [UniParc].

Last modified May 29, 2007. Version 1.
Checksum: 16D4EE89694AC7C1

FASTA18520,089
        10         20         30         40         50         60 
MLIVIVGPMF AGKTTELIRR VERYVIAGKR AIVFKPSIDA RYDSSKVAAH NGLKFGAYVV 

        70         80         90        100        110        120 
PPDEAGVEAI GKLGLDYDVV AVDEIQFFPP SLADVLNGLA DGRVVIAAGL NLDFRGEPFE 

       130        140        150        160        170        180 
TTMRTMAFAD RVISLTAVCK VCGRPATRTQ RLINGLPAPR DSPRILVGGG DSYEARCRRH 


YVRPA 

« Hide

References

[1]"Complete sequence of Pyrobaculum arsenaticum DSM 13514."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N. expand/collapse author list , Cozen A.E., Fitz-Gibbon S.T., House C.H., Saltikov C., Lowe T.M., Richardson P.
Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DSM 13514 / JCM 11321.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000660 Genomic DNA. Translation: ABP50985.1.
RefSeqYP_001153637.1. NC_009376.1.

3D structure databases

ProteinModelPortalA4WKR8.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING340102.Pars_1427.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABP50985; ABP50985; Pars_1427.
GeneID5054788.
KEGGpas:Pars_1427.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1435.
HOGENOMHOG000076390.
KOK00857.
OMAELICGSM.
ProtClustDBPRK04296.

Enzyme and pathway databases

BioCycPARS340102:GHGQ-1442-MONOMER.

Family and domain databases

HAMAPMF_00124. Thymidine_kinase.
InterProIPR027417. P-loop_NTPase.
IPR001267. Thymidine_kinase.
IPR020633. Thymidine_kinase_CS.
IPR020634. Thymidine_kinase_subgr.
[Graphical view]
PANTHERPTHR11441. PTHR11441. 1 hit.
PfamPF00265. TK. 1 hit.
[Graphical view]
PIRSFPIRSF035805. TK_cell. 1 hit.
SUPFAMSSF52540. SSF52540. 1 hit.
PROSITEPS00603. TK_CELLULAR_TYPE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameA4WKR8_PYRAR
AccessionPrimary (citable) accession number: A4WKR8
Entry history
Integrated into UniProtKB/TrEMBL: May 29, 2007
Last sequence update: May 29, 2007
Last modified: April 16, 2014
This is version 47 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)