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Protein

Phosphoenolpyruvate carboxylase

Gene

ppcA

Organism
Pyrobaculum arsenaticum (strain DSM 13514 / JCM 11321)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotation

Cofactori

Mg2+UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Lyase

Keywords - Biological processi

Carbon dioxide fixation

Keywords - Ligandi

Magnesium

Enzyme and pathway databases

BioCyciPARS340102:GHGQ-1027-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotation (EC:4.1.1.31UniRule annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcAUniRule annotation
Ordered Locus Names:Pars_1014
OrganismiPyrobaculum arsenaticum (strain DSM 13514 / JCM 11321)
Taxonomic identifieri340102 [NCBI]
Taxonomic lineageiArchaeaCrenarchaeotaThermoproteiThermoprotealesThermoproteaceaePyrobaculum
ProteomesiUP000001567 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 460460Phosphoenolpyruvate carboxylasePRO_0000309608Add
BLAST

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 2 family.UniRule annotation

Phylogenomic databases

eggNOGiCOG1892.
HOGENOMiHOG000009826.
KOiK01595.
OMAiQSAFRYD.

Family and domain databases

HAMAPiMF_01904. PEPcase_type2.
InterProiIPR007566. PEP_COase_arc-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF14010. PEPcase_2. 1 hit.
[Graphical view]
PIRSFiPIRSF006677. UCP006677. 1 hit.
SUPFAMiSSF51621. SSF51621. 1 hit.
TIGRFAMsiTIGR02751. PEPCase_arch. 1 hit.

Sequencei

Sequence statusi: Complete.

A4WJM7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MMHIPRLMCT QHPDTTVKIT TAEEVDEAIV AYTAYGCDEV MVDYEGKMTP
60 70 80 90 100
YGQPKEIVMK AIRGDVPLGD EFYITVRLPN PKLEEFDRAM LSLEAALVAN
110 120 130 140 150
YFSRRYADAQ AVRWVVLPMV EDFDTVILVR RMLRRKAEIY KSETGVDVGE
160 170 180 190 200
VEVIPLIEDA FVQVKAKVIV GEVFKSEEAR EVRVFLGKSD SAVRHGHLAS
210 220 230 240 250
ALAIIYAMSK LKEFEAESGI RVRPILGMGS PPFRGALNNP RLAHLEVVQY
260 270 280 290 300
AGYYTATIQS AVRYDTSLDE YVKVRESILN ACCGTRGLVG EEVLPLIQEA
310 320 330 340 350
SAKYRSQAMK HVDKIAEVAR LVPSTRDRVS WKEYGRSLLD GDRVVHMPRA
360 370 380 390 400
IVYTSAWYAM GFPPTLIDAP LLLELAKSDK LDAVFKLLPT YKMELEYDYE
410 420 430 440 450
FFDPQTARNY LSEELVYAAV ELADYLGVEA RPTPTYTALL KMPRSEPNII
460
ALSKYRKFLG
Length:460
Mass (Da):51,926
Last modified:May 29, 2007 - v1
Checksum:iBC72C5AC78BD73DC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000660 Genomic DNA. Translation: ABP50594.1.
RefSeqiWP_011900501.1. NC_009376.1.
YP_001153246.1. NC_009376.1.

Genome annotation databases

EnsemblBacteriaiABP50594; ABP50594; Pars_1014.
GeneIDi5054751.
KEGGipas:Pars_1014.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000660 Genomic DNA. Translation: ABP50594.1.
RefSeqiWP_011900501.1. NC_009376.1.
YP_001153246.1. NC_009376.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABP50594; ABP50594; Pars_1014.
GeneIDi5054751.
KEGGipas:Pars_1014.

Phylogenomic databases

eggNOGiCOG1892.
HOGENOMiHOG000009826.
KOiK01595.
OMAiQSAFRYD.

Enzyme and pathway databases

BioCyciPARS340102:GHGQ-1027-MONOMER.

Family and domain databases

HAMAPiMF_01904. PEPcase_type2.
InterProiIPR007566. PEP_COase_arc-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF14010. PEPcase_2. 1 hit.
[Graphical view]
PIRSFiPIRSF006677. UCP006677. 1 hit.
SUPFAMiSSF51621. SSF51621. 1 hit.
TIGRFAMsiTIGR02751. PEPCase_arch. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 13514 / JCM 11321.

Entry informationi

Entry nameiCAPPA_PYRAR
AccessioniPrimary (citable) accession number: A4WJM7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 13, 2007
Last sequence update: May 29, 2007
Last modified: July 22, 2015
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.