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A4WJK1 (SURE_PYRAR) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 49. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
5'-nucleotidase SurE

EC=3.1.3.5
Alternative name(s):
Nucleoside 5'-monophosphate phosphohydrolase
Gene names
Name:surE
Ordered Locus Names:Pars_0988
OrganismPyrobaculum arsenaticum (strain DSM 13514 / JCM 11321) [Complete proteome] [HAMAP]
Taxonomic identifier340102 [NCBI]
Taxonomic lineageArchaeaCrenarchaeotaThermoproteiThermoprotealesThermoproteaceaePyrobaculum

Protein attributes

Sequence length266 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates By similarity. HAMAP-Rule MF_00060

Catalytic activity

A 5'-ribonucleotide + H2O = a ribonucleoside + phosphate. HAMAP-Rule MF_00060

Cofactor

Binds 1 divalent metal cation per subunit By similarity.

Subcellular location

Cytoplasm Potential HAMAP-Rule MF_00060.

Sequence similarities

Belongs to the SurE nucleotidase family.

Ontologies

Keywords
   Cellular componentCytoplasm
   LigandMetal-binding
Nucleotide-binding
   Molecular functionHydrolase
   Technical termComplete proteome
Gene Ontology (GO)
   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_function5'-nucleotidase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

metal ion binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

nucleotide binding

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 2662665'-nucleotidase SurE HAMAP-Rule MF_00060
PRO_1000007775

Sites

Metal binding81Divalent metal cation By similarity
Metal binding91Divalent metal cation By similarity
Metal binding391Divalent metal cation By similarity
Metal binding931Divalent metal cation By similarity

Sequences

Sequence LengthMass (Da)Tools
A4WJK1 [UniParc].

Last modified May 29, 2007. Version 1.
Checksum: ADBEB0EBB5161929

FASTA26628,979
        10         20         30         40         50         60 
MRILITNDDG VHSPGLRLLY EFASPLGAVD VVAPESPKSA TGLGITLHKP LRMYETDLCG 

        70         80         90        100        110        120 
FKAVATSGTP SDTIYLAAYG LGRRYDLVLS GINLGDNTSL QVILSSGTLG AAFQAALLGI 

       130        140        150        160        170        180 
PAVAYSLHAQ DWEEVLKNRE ALEIMKAVVQ KSAEFVLKYG LPHGVDVVSI NFPRNMKRGV 

       190        200        210        220        230        240 
KAKLVRAAKF RFAQKVDRRV DPRGSSYYWL YGTDLAPEPD TDVYTVLVEG QIAVTPLTLD 

       250        260 
LNALNTDRKL DAEALAKLVR YINEAI 

« Hide

References

[1]"Complete sequence of Pyrobaculum arsenaticum DSM 13514."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N. expand/collapse author list , Cozen A.E., Fitz-Gibbon S.T., House C.H., Saltikov C., Lowe T.M., Richardson P.
Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DSM 13514 / JCM 11321.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000660 Genomic DNA. Translation: ABP50568.1.
RefSeqYP_001153220.1. NC_009376.1.

3D structure databases

ProteinModelPortalA4WJK1.
SMRA4WJK1. Positions 1-266.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING340102.Pars_0988.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABP50568; ABP50568; Pars_0988.
GeneID5055443.
KEGGpas:Pars_0988.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0496.
HOGENOMHOG000122501.
KOK03787.
OMAYFAPGIA.

Enzyme and pathway databases

BioCycPARS340102:GHGQ-999-MONOMER.

Family and domain databases

Gene3D3.40.1210.10. 1 hit.
HAMAPMF_00060. SurE.
InterProIPR002828. SurE-like_Pase/nucleotidase.
[Graphical view]
PfamPF01975. SurE. 1 hit.
[Graphical view]
SUPFAMSSF64167. SSF64167. 1 hit.
TIGRFAMsTIGR00087. surE. 1 hit.
ProtoNetSearch...

Entry information

Entry nameSURE_PYRAR
AccessionPrimary (citable) accession number: A4WJK1
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: May 29, 2007
Last modified: May 14, 2014
This is version 49 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families