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A4WJK1

- SURE_PYRAR

UniProt

A4WJK1 - SURE_PYRAR

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Protein

5'-nucleotidase SurE

Gene
surE, Pars_0988
Organism
Pyrobaculum arsenaticum (strain DSM 13514 / JCM 11321)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates By similarity.UniRule annotation

Catalytic activityi

A 5'-ribonucleotide + H2O = a ribonucleoside + phosphate.UniRule annotation

Cofactori

Binds 1 divalent metal cation per subunit By similarity.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi8 – 81Divalent metal cation By similarity
Metal bindingi9 – 91Divalent metal cation By similarity
Metal bindingi39 – 391Divalent metal cation By similarity
Metal bindingi93 – 931Divalent metal cation By similarity

GO - Molecular functioni

  1. 5'-nucleotidase activity Source: UniProtKB-HAMAP
  2. metal ion binding Source: UniProtKB-HAMAP
  3. nucleotide binding Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Ligandi

Metal-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciPARS340102:GHGQ-999-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
5'-nucleotidase SurE (EC:3.1.3.5)
Alternative name(s):
Nucleoside 5'-monophosphate phosphohydrolase
Gene namesi
Name:surE
Ordered Locus Names:Pars_0988
OrganismiPyrobaculum arsenaticum (strain DSM 13514 / JCM 11321)
Taxonomic identifieri340102 [NCBI]
Taxonomic lineageiArchaeaCrenarchaeotaThermoproteiThermoprotealesThermoproteaceaePyrobaculum
ProteomesiUP000001567: Chromosome

Subcellular locationi

Cytoplasm Reviewed prediction UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 2662665'-nucleotidase SurEUniRule annotationPRO_1000007775Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi340102.Pars_0988.

Structurei

3D structure databases

ProteinModelPortaliA4WJK1.
SMRiA4WJK1. Positions 1-266.

Family & Domainsi

Sequence similaritiesi

Belongs to the SurE nucleotidase family.

Phylogenomic databases

eggNOGiCOG0496.
HOGENOMiHOG000122501.
KOiK03787.
OMAiYFAPGIA.

Family and domain databases

Gene3Di3.40.1210.10. 1 hit.
HAMAPiMF_00060. SurE.
InterProiIPR002828. SurE-like_Pase/nucleotidase.
[Graphical view]
PfamiPF01975. SurE. 1 hit.
[Graphical view]
SUPFAMiSSF64167. SSF64167. 1 hit.
TIGRFAMsiTIGR00087. surE. 1 hit.

Sequencei

Sequence statusi: Complete.

A4WJK1-1 [UniParc]FASTAAdd to Basket

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MRILITNDDG VHSPGLRLLY EFASPLGAVD VVAPESPKSA TGLGITLHKP    50
LRMYETDLCG FKAVATSGTP SDTIYLAAYG LGRRYDLVLS GINLGDNTSL 100
QVILSSGTLG AAFQAALLGI PAVAYSLHAQ DWEEVLKNRE ALEIMKAVVQ 150
KSAEFVLKYG LPHGVDVVSI NFPRNMKRGV KAKLVRAAKF RFAQKVDRRV 200
DPRGSSYYWL YGTDLAPEPD TDVYTVLVEG QIAVTPLTLD LNALNTDRKL 250
DAEALAKLVR YINEAI 266
Length:266
Mass (Da):28,979
Last modified:May 29, 2007 - v1
Checksum:iADBEB0EBB5161929
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000660 Genomic DNA. Translation: ABP50568.1.
RefSeqiYP_001153220.1. NC_009376.1.

Genome annotation databases

EnsemblBacteriaiABP50568; ABP50568; Pars_0988.
GeneIDi5055443.
KEGGipas:Pars_0988.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000660 Genomic DNA. Translation: ABP50568.1 .
RefSeqi YP_001153220.1. NC_009376.1.

3D structure databases

ProteinModelPortali A4WJK1.
SMRi A4WJK1. Positions 1-266.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 340102.Pars_0988.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABP50568 ; ABP50568 ; Pars_0988 .
GeneIDi 5055443.
KEGGi pas:Pars_0988.

Phylogenomic databases

eggNOGi COG0496.
HOGENOMi HOG000122501.
KOi K03787.
OMAi YFAPGIA.

Enzyme and pathway databases

BioCyci PARS340102:GHGQ-999-MONOMER.

Family and domain databases

Gene3Di 3.40.1210.10. 1 hit.
HAMAPi MF_00060. SurE.
InterProi IPR002828. SurE-like_Pase/nucleotidase.
[Graphical view ]
Pfami PF01975. SurE. 1 hit.
[Graphical view ]
SUPFAMi SSF64167. SSF64167. 1 hit.
TIGRFAMsi TIGR00087. surE. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 13514 / JCM 11321.

Entry informationi

Entry nameiSURE_PYRAR
AccessioniPrimary (citable) accession number: A4WJK1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: May 29, 2007
Last modified: May 14, 2014
This is version 49 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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