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Protein

HTH-type transcriptional activator RhaR

Gene

rhaR

Organism
Enterobacter sp. (strain 638)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Activates expression of the rhaSR operon in response to L-rhamnose.UniRule annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi195 – 214H-T-H motifUniRule annotationAdd BLAST20
DNA bindingi244 – 267H-T-H motifUniRule annotationAdd BLAST24

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionActivator, DNA-binding
Biological processRhamnose metabolism, Transcription, Transcription regulation

Names & Taxonomyi

Protein namesi
Recommended name:
HTH-type transcriptional activator RhaRUniRule annotation
Alternative name(s):
L-rhamnose operon transcriptional activator RhaRUniRule annotation
Gene namesi
Name:rhaRUniRule annotation
Ordered Locus Names:Ent638_4065
OrganismiEnterobacter sp. (strain 638)
Taxonomic identifieri399742 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEnterobacter
Proteomesi
  • UP000000230 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000686961 – 282HTH-type transcriptional activator RhaRAdd BLAST282

Interactioni

Subunit structurei

Binds DNA as a dimer.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sitei246Interaction with sigma-70UniRule annotation1

Protein-protein interaction databases

STRINGi399742.Ent638_4065.

Structurei

3D structure databases

ProteinModelPortaliA4WG90.
SMRiA4WG90.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

Repeat

Phylogenomic databases

eggNOGiENOG4108BRW. Bacteria.
ENOG410XYX0. LUCA.
HOGENOMiHOG000290513.
KOiK02854.
OMAiDWAAHIP.

Family and domain databases

HAMAPiMF_01533. HTH_type_RhaR. 1 hit.
InterProiView protein in InterPro
IPR003313. AraC-bd.
IPR009057. Homeobox-like.
IPR018060. HTH_AraC.
IPR018062. HTH_AraC-typ_CS.
IPR011051. RmlC_Cupin.
IPR023699. Tscrpt_act_RhaR.
IPR020449. Tscrpt_reg_HTH_AraC-type.
PfamiView protein in Pfam
PF02311. AraC_binding. 1 hit.
PF12833. HTH_18. 1 hit.
PRINTSiPR00032. HTHARAC.
SMARTiView protein in SMART
SM00342. HTH_ARAC. 1 hit.
SUPFAMiSSF46689. SSF46689. 1 hit.
SSF51182. SSF51182. 1 hit.
PROSITEiView protein in PROSITE
PS00041. HTH_ARAC_FAMILY_1. 1 hit.
PS01124. HTH_ARAC_FAMILY_2. 1 hit.

Sequencei

Sequence statusi: Complete.

A4WG90-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGVPLILRKT DFFANAGQAV AVADRYPQNV FAEHTHEFCE LVLVWRGNGL
60 70 80 90 100
HVLNDRPYRI TRGDLFYIRA EDKHSYASVN DLVLQNVIYC PDRLKLNVDW
110 120 130 140 150
ASNIPGFNDA RGAPHWRLSS NGMGQVRPVI TQLEQESLKA DQSANEMAEL
160 170 180 190 200
LFAQLVMTLK RFRYATDNPS ANEQEALLDK LITALAGSLN RSFVLEKFCE
210 220 230 240 250
QEQCSERALR QQFRTQTGMT VNHYLRQLRI CHAQYLLQHT ELMVSEVAMR
260 270 280
CGFEDSNYFS VVFNREVGMT PVQWRHRSRK AA
Length:282
Mass (Da):32,428
Last modified:May 29, 2007 - v1
Checksum:i99D2CF9138688358
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000653 Genomic DNA. Translation: ABP62720.1.
RefSeqiWP_015961024.1. NC_009436.1.

Genome annotation databases

EnsemblBacteriaiABP62720; ABP62720; Ent638_4065.
KEGGient:Ent638_4065.
PATRICi20417915. VBIEntSp101211_4230.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000653 Genomic DNA. Translation: ABP62720.1.
RefSeqiWP_015961024.1. NC_009436.1.

3D structure databases

ProteinModelPortaliA4WG90.
SMRiA4WG90.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi399742.Ent638_4065.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABP62720; ABP62720; Ent638_4065.
KEGGient:Ent638_4065.
PATRICi20417915. VBIEntSp101211_4230.

Phylogenomic databases

eggNOGiENOG4108BRW. Bacteria.
ENOG410XYX0. LUCA.
HOGENOMiHOG000290513.
KOiK02854.
OMAiDWAAHIP.

Family and domain databases

HAMAPiMF_01533. HTH_type_RhaR. 1 hit.
InterProiView protein in InterPro
IPR003313. AraC-bd.
IPR009057. Homeobox-like.
IPR018060. HTH_AraC.
IPR018062. HTH_AraC-typ_CS.
IPR011051. RmlC_Cupin.
IPR023699. Tscrpt_act_RhaR.
IPR020449. Tscrpt_reg_HTH_AraC-type.
PfamiView protein in Pfam
PF02311. AraC_binding. 1 hit.
PF12833. HTH_18. 1 hit.
PRINTSiPR00032. HTHARAC.
SMARTiView protein in SMART
SM00342. HTH_ARAC. 1 hit.
SUPFAMiSSF46689. SSF46689. 1 hit.
SSF51182. SSF51182. 1 hit.
PROSITEiView protein in PROSITE
PS00041. HTH_ARAC_FAMILY_1. 1 hit.
PS01124. HTH_ARAC_FAMILY_2. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiRHAR_ENT38
AccessioniPrimary (citable) accession number: A4WG90
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: May 29, 2007
Last modified: May 10, 2017
This is version 72 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.