Reviewed, UniProtKB/Swiss-Prot A4WG79 (CDH_ENT38)

Names and origin

Protein names

Recommended name:
    CDP-diacylglycerol pyrophosphatase
    EC=3.6.1.26
Alternative name(s):
    CDP-diacylglycerol phosphatidylhydrolase
    CDP-diglyceride hydrolase

Gene names

Name:	cdh
Ordered Locus Names:	Ent638_4054

Organism

Enterobacter sp. (strain 638) [Complete proteome] [HAMAP]

Taxonomic identifier

399742 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Enterobacter

Protein attributes

Sequence length	247 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	CDP-diacylglycerol + H2O = CMP + phosphatidate. HAMAP MF_00319
Pathway	Phospholipid metabolism; CDP-diacylglycerol degradation; phosphatidate from CDP-diacylglycerol: step 1/1. HAMAP MF_00319
Subcellular location	Cell inner membrane; Single-pass membrane protein By similarity.
Sequence similarities	Belongs to the cdh family.

Ontologies

Keywords
Biological process	Phospholipid biosynthesis
Cellular component	Cell inner membrane Cell membrane Membrane
Domain	Transmembrane
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	phospholipid biosynthetic process Inferred from electronic annotation. Source: HAMAP
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	CDP-diacylglycerol diphosphatase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 247	247	CDP-diacylglycerol pyrophosphatase HAMAP MF_00319		PRO_1000059465
Regions
	Transmembrane	5 – 22	18	Potential

Sequences

	Sequence		Length	Mass (Da)
	A4WG79-1 [UniParc]. Last modified May 29, 2007. Version 1. Checksum: 6B96652AEB05062B	FASTA	247	27,881
	10 20 30 40 50 60 MKKLIVLALV VSVAVAGGWL WMKSGNPDAL RHIVLEQCLV NQQQHRNPAP CAQVKPDAGY 70 80 90 100 110 120 VVFKDRNGPL QYLLMPTYRI NGTESPLLTE PQTPNFFWLA WQSRNFMSMK RGTEVPDSAI 130 140 150 160 170 180 ALTINSPTGR TQNHFHIHIS CLRPDVREKL DANQGQISTQ WLPFPGGLEG HEYLARRVTE 190 200 210 220 230 240 AELVKRSPFM MLAQELPQAR EHMGRFAMAM AQQSDGSFVL LATERNLLVL NRASAEELQD HQCDILN

References

[1]

"Complete sequence of chromosome of Enterobacter sp. 638." Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Kiss H., Brettin T., Bruce D., Detter J.C., Han C., Tapia R., Gilna P., Schmutz J., Larimer F., Land M. , Hauser L., Kyrpides N., Kim E., Taghavi S., Newman L., Vangronsveld J., van der Lelie D., Richardson P. Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000653 Genomic DNA. Translation: ABP62709.1.
RefSeq	YP_001178760.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	5110808.
GenomeReviews	Gene locus Ent638_4054 in contig CP000653_GR.
KEGG	ent:Ent638_4054.
NMPDR	fig|399742.4.peg.3856.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	A4WG79. EIQDHEC.
Family and domain databases
HAMAP	MF_00319. [Tree]
InterPro	IPR003763. CDP-diacylglyc_Pase_bac. IPR015993. CDP-diacylglyc_Pase_proteobac. [Graphical view]
Pfam	PF02611. CDH. 1 hit. [Graphical view]
PIRSF	PIRSF001273. CDH. 1 hit.
TIGRFAMs	TIGR00672. cdh. 1 hit.
ProtoNet	Search...

Entry information

Entry name

CDH_ENT38

Accession

Primary (citable) accession number: A4WG79

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 5, 2008
Last sequence update:	May 29, 2007
Last modified:	June 16, 2009
This is version 14 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)