Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

ATP-dependent RNA helicase RhlB

Gene

rhlB

Organism
Enterobacter sp. (strain 638)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA.

Catalytic activityi

ATP + H2O = ADP + phosphate.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi53 – 60ATP8

GO - Molecular functioni

Keywordsi

Molecular functionHelicase, Hydrolase, RNA-binding
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
ATP-dependent RNA helicase RhlB (EC:3.6.4.13)
Gene namesi
Name:rhlB
Ordered Locus Names:Ent638_4005
OrganismiEnterobacter sp. (strain 638)
Taxonomic identifieri399742 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEnterobacter
Proteomesi
  • UP000000230 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000828431 – 421ATP-dependent RNA helicase RhlBAdd BLAST421

Proteomic databases

PRIDEiA4WG30.

Interactioni

Subunit structurei

Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.

Protein-protein interaction databases

STRINGi399742.Ent638_4005.

Structurei

3D structure databases

ProteinModelPortaliA4WG30.
SMRiA4WG30.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini40 – 219Helicase ATP-bindingAdd BLAST180
Domaini245 – 390Helicase C-terminalAdd BLAST146

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi9 – 37Q motifAdd BLAST29
Motifi165 – 168DEAD box4

Sequence similaritiesi

Belongs to the DEAD box helicase family. RhlB subfamily.

Phylogenomic databases

eggNOGiENOG4105C1J. Bacteria.
COG0513. LUCA.
HOGENOMiHOG000268807.
KOiK03732.
OMAiDEMPVNA.

Family and domain databases

CDDicd00079. HELICc. 1 hit.
HAMAPiMF_00661. DEAD_helicase_RhlB. 1 hit.
InterProiView protein in InterPro
IPR011545. DEAD/DEAH_box_helicase_dom.
IPR014001. Helicase_ATP-bd.
IPR001650. Helicase_C.
IPR027417. P-loop_NTPase.
IPR000629. RNA-helicase_DEAD-box_CS.
IPR023554. RNA_helicase_ATP-dep_RhlB.
IPR014014. RNA_helicase_DEAD_Q_motif.
PfamiView protein in Pfam
PF00270. DEAD. 1 hit.
PF00271. Helicase_C. 1 hit.
SMARTiView protein in SMART
SM00487. DEXDc. 1 hit.
SM00490. HELICc. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiView protein in PROSITE
PS00039. DEAD_ATP_HELICASE. 1 hit.
PS51192. HELICASE_ATP_BIND_1. 1 hit.
PS51194. HELICASE_CTER. 1 hit.
PS51195. Q_MOTIF. 1 hit.

Sequencei

Sequence statusi: Complete.

A4WG30-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSKTHLTEQK FSDFALHAKV IEALENKGFH YCTPIQALAL PLTLAGRDVA
60 70 80 90 100
GQAQTGTGKT MAFLTSAFHY LLSNPAMADR KVNQPRALIM APTRELAVQI
110 120 130 140 150
HADAEPLAQT TGLKLGLAYG GDGYDKQLKV LESGVDILIG TTGRLIDYAK
160 170 180 190 200
QNHINLGAIQ VVVLDEADRM YDLGFIKDIR WLFRRMPPTP QRLNMLFSAT
210 220 230 240 250
LSYRVRELAF EQMNNAEYVE VEPEQKTGHR IKEELFYPSN EEKMRLLQTL
260 270 280 290 300
IEEEWPDRAI IFANTKHRCE DIWGHLAADG HRVGLLTGDV AQKKRLRILE
310 320 330 340 350
DFTRGDLDIL VATDVAARGL HIPAVTHVFN YDLPDDCEDY VHRIGRTGRA
360 370 380 390 400
GASGHSISLA CEEYALNLTA IETYIGHSVP QSKYNPDALL SELPPPKRLT
410 420
RARSGNGPRR TGAPRNRRRP G
Length:421
Mass (Da):47,083
Last modified:May 29, 2007 - v1
Checksum:i1D2BC052DA626058
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000653 Genomic DNA. Translation: ABP62660.1.
RefSeqiWP_015960964.1. NC_009436.1.

Genome annotation databases

EnsemblBacteriaiABP62660; ABP62660; Ent638_4005.
GeneIDi32444596.
KEGGient:Ent638_4005.

Similar proteinsi

Entry informationi

Entry nameiRHLB_ENT38
AccessioniPrimary (citable) accession number: A4WG30
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: May 29, 2007
Last modified: October 25, 2017
This is version 68 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families