ID   HEM6_ENT38              Reviewed;         299 AA.
AC   A4WD41;
DT   05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   29-MAY-2007, sequence version 1.
DT   16-JUN-2009, entry version 16.
DE   RecName: Full=Coproporphyrinogen-III oxidase, aerobic;
DE            Short=Coproporphyrinogenase;
DE            Short=Coprogen oxidase;
DE            EC=1.3.3.3;
GN   Name=hemF; OrderedLocusNames=Ent638_2957;
OS   Enterobacter sp. (strain 638).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales;
OC   Enterobacteriaceae; Enterobacter.
OX   NCBI_TaxID=399742;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T.,
RA   Dalin E., Tice H., Pitluck S., Kiss H., Brettin T., Bruce D.,
RA   Detter J.C., Han C., Tapia R., Gilna P., Schmutz J., Larimer F.,
RA   Land M., Hauser L., Kyrpides N., Kim E., Taghavi S., Newman L.,
RA   Vangronsveld J., van der Lelie D., Richardson P.;
RT   "Complete sequence of chromosome of Enterobacter sp. 638.";
RL   Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY: Coproporphyrinogen-III + O(2) + 2 H(+) =
CC       protoporphyrinogen-IX + 2 CO(2) + 2 H(2)O.
CC   -!- PATHWAY: Porphyrin metabolism; protoporphyrin-IX biosynthesis;
CC       protoporphyrinogen-IX from coproporphyrinogen-III (O2 route): step
CC       1/1.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- SIMILARITY: Belongs to the aerobic coproporphyrinogen-III oxidase
CC       family.
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DR   EMBL; CP000653; ABP61621.1; -; Genomic_DNA.
DR   RefSeq; YP_001177672.1; -.
DR   GeneID; 5112493; -.
DR   GenomeReviews; CP000653_GR; Ent638_2957.
DR   KEGG; ent:Ent638_2957; -.
DR   NMPDR; fig|399742.4.peg.2823; -.
DR   OMA; A4WD41; VKAYLLD.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0004109; F:coproporphyrinogen oxidase activity; IEA:HAMAP.
DR   GO; GO:0055114; P:oxidation reduction; IEA:UniProtKB-KW.
DR   GO; GO:0006779; P:porphyrin biosynthetic process; IEA:HAMAP.
DR   HAMAP; MF_00333; -; 1.
DR   InterPro; IPR001260; Coprogen_oxidas.
DR   InterPro; IPR018375; Coproporphyrinogen-3_ox_CS.
DR   PANTHER; PTHR10755; Coprogen_oxidas; 1.
DR   Pfam; PF01218; Coprogen_oxidas; 1.
DR   PIRSF; PIRSF000166; Coproporphyri_ox; 1.
DR   PRINTS; PR00073; COPRGNOXDASE.
DR   PROSITE; PS01021; COPROGEN_OXIDASE; 1.
PE   3: Inferred from homology;
KW   Complete proteome; Cytoplasm; Oxidoreductase; Porphyrin biosynthesis.
FT   CHAIN         1    299       Coproporphyrinogen-III oxidase, aerobic.
FT                                /FTId=PRO_1000059706.
SQ   SEQUENCE   299 AA;  34258 MW;  E9BB793CBE4CCEBF CRC64;
     MKPNVQQVKT FLMQLQDDIC QKLSAVDGGE FHEDSWQREA GGGGRSRVLR NGGVFEQAGV
     NFSHVHGDAM PASATAHRPE LAGRSFEAMG VSLVVHPQSP FVPTSHANVR FFIAEKPGAD
     PVWWFGGGFD LTPYYGFEED AVHWHRTARD ICQPFGEEVY PKYKKWCDDY FYLKHRDEQR
     GIGGLFFDDL NAPDFDTAFN FMQAVGQGYT DAYLPIVERR RNTDYGVRER EFQLYRRGRY
     VEFNLVWDRG TLFGLQTGGR TESILMSMPP LVRWEYSFEP KEGSPEAALA EFIKVRDWI
//