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Protein

Probable malate:quinone oxidoreductase

Gene

mqo

Organism
Enterobacter sp. (strain 638)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

(S)-malate + a quinone = oxaloacetate + reduced quinone.UniRule annotation

Cofactori

FADUniRule annotation

Pathwayi: tricarboxylic acid cycle

This protein is involved in step 1 of the subpathway that synthesizes oxaloacetate from (S)-malate (quinone route).UniRule annotation
Proteins known to be involved in this subpathway in this organism are:
  1. Probable malate:quinone oxidoreductase (mqo)
This subpathway is part of the pathway tricarboxylic acid cycle, which is itself part of Carbohydrate metabolism.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes oxaloacetate from (S)-malate (quinone route), the pathway tricarboxylic acid cycle and in Carbohydrate metabolism.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductase
Biological processTricarboxylic acid cycle
LigandFAD, Flavoprotein

Enzyme and pathway databases

UniPathwayiUPA00223; UER01008.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable malate:quinone oxidoreductaseUniRule annotation (EC:1.1.5.4UniRule annotation)
Alternative name(s):
MQOUniRule annotation
Malate dehydrogenase [quinone]UniRule annotation
Gene namesi
Name:mqoUniRule annotation
Ordered Locus Names:Ent638_2788
OrganismiEnterobacter sp. (strain 638)
Taxonomic identifieri399742 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEnterobacter
Proteomesi
  • UP000000230 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003254951 – 551Probable malate:quinone oxidoreductaseAdd BLAST551

Proteomic databases

PRIDEiA4WCM3.

Interactioni

Protein-protein interaction databases

STRINGi399742.Ent638_2788.

Structurei

3D structure databases

ProteinModelPortaliA4WCM3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the MQO family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105DWT. Bacteria.
COG0579. LUCA.
HOGENOMiHOG000109379.
KOiK00116.
OMAiEPIAATK.

Family and domain databases

Gene3Di3.50.50.60. 1 hit.
HAMAPiMF_00212. MQO. 1 hit.
InterProiView protein in InterPro
IPR036188. FAD/NAD-bd_sf.
IPR006231. MQO.
PfamiView protein in Pfam
PF06039. Mqo. 1 hit.
SUPFAMiSSF51905. SSF51905. 2 hits.
TIGRFAMsiTIGR01320. mal_quin_oxido. 1 hit.

Sequencei

Sequence statusi: Complete.

A4WCM3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKKMTAMLFS MAVGLNAVSM TAMADAPKEQ ETDVLLIGGG IMSATLGTYL
60 70 80 90 100
QELQPDWSMT MVERLDGVAK ESSNGWNNAG TGHSALMELN YTPQKKDGSI
110 120 130 140 150
SIEKAVEINE AFQVSRQFWS HQVNSGVMHD PHSFINTVPH MSFVWGDQNV
160 170 180 190 200
NFLRARYAAL QQSSLFRGMK FSEDHAQIKE WAPLVMEGRD PNQKVAATRT
210 220 230 240 250
EIGTDVNYGE ITHQLVASLQ KKDDFHLQLS TEVRGFKRNA DNSWSVTVAD
260 270 280 290 300
LKNNEAEHVI KAKFVFIGAG GAALKLLQET GIPEADDYAG FPVGGQFLVS
310 320 330 340 350
ENPEVVNRHL AKVYGQASVG APPMSVPHID TRMLDGKRVV LFGPFATFST
360 370 380 390 400
KFLKNGSLWD LLSSTTTSNF MPMVDVGMDN FDLVKYLMSQ VMLSDDDRFA
410 420 430 440 450
ALQEYYPQAK KEDWRLWQAG QRVQIIKRDP KEGGVLRLGT EVVSDKEGTI
460 470 480 490 500
AALLGASPGA STAAPIMLHL MEKVFKDKVA SPEWQAKLKT IIPSYGTKLN
510 520 530 540 550
GNVAATEQEL EFTSRVLQLK YEKPQTAAAA PQAQPQLKPQ PDAKPVADIA

L
Length:551
Mass (Da):60,670
Last modified:March 18, 2008 - v2
Checksum:i8FCB867FCC2F81BE
GO

Sequence cautioni

The sequence ABP61453 differs from that shown. Reason: Erroneous initiation.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000653 Genomic DNA. Translation: ABP61453.1. Different initiation.
RefSeqiWP_041689471.1. NC_009436.1.

Genome annotation databases

EnsemblBacteriaiABP61453; ABP61453; Ent638_2788.
GeneIDi32441023.
KEGGient:Ent638_2788.

Similar proteinsi

Entry informationi

Entry nameiMQO_ENT38
AccessioniPrimary (citable) accession number: A4WCM3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 18, 2008
Last sequence update: March 18, 2008
Last modified: October 25, 2017
This is version 68 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families