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A4WCM3 (MQO_ENT38) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 37. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Probable malate:quinone oxidoreductase
EC=1.1.5.4
Alternative name(s):
MQO
Malate dehydrogenase [quinone]
Gene names
Name:mqo
Ordered Locus Names:Ent638_2788
OrganismEnterobacter sp. (strain 638) [Complete proteome] [HAMAP]
Taxonomic identifier399742 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Enterobacter

Protein attributes

Sequence length551 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

(S)-malate + a quinone = oxaloacetate + reduced quinone. HAMAP MF_00212

Cofactor

FAD By similarity. HAMAP MF_00212

Pathway

Carbohydrate metabolism; tricarboxylic acid cycle; oxaloacetate from (S)-malate (quinone route): step 1/1. HAMAP MF_00212

Sequence similarities

Belongs to the MQO family.

Sequence caution

The sequence ABP61453.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
   Biological processTricarboxylic acid cycle
   LigandFAD
Flavoprotein
   Molecular functionOxidoreductase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processtricarboxylic acid cycle

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular functionmalate dehydrogenase (menaquinone) activity

Inferred from electronic annotation. Source: EC

malate dehydrogenase (quinone) activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 551551Probable malate:quinone oxidoreductase HAMAP MF_00212
PRO_0000325495

Sequences

Sequence LengthMass (Da)Tools
A4WCM3 [UniParc].

Last modified March 18, 2008. Version 2.
Checksum: 8FCB867FCC2F81BE

FASTA55160,670
        10         20         30         40         50         60 
MKKMTAMLFS MAVGLNAVSM TAMADAPKEQ ETDVLLIGGG IMSATLGTYL QELQPDWSMT 

        70         80         90        100        110        120 
MVERLDGVAK ESSNGWNNAG TGHSALMELN YTPQKKDGSI SIEKAVEINE AFQVSRQFWS 

       130        140        150        160        170        180 
HQVNSGVMHD PHSFINTVPH MSFVWGDQNV NFLRARYAAL QQSSLFRGMK FSEDHAQIKE 

       190        200        210        220        230        240 
WAPLVMEGRD PNQKVAATRT EIGTDVNYGE ITHQLVASLQ KKDDFHLQLS TEVRGFKRNA 

       250        260        270        280        290        300 
DNSWSVTVAD LKNNEAEHVI KAKFVFIGAG GAALKLLQET GIPEADDYAG FPVGGQFLVS 

       310        320        330        340        350        360 
ENPEVVNRHL AKVYGQASVG APPMSVPHID TRMLDGKRVV LFGPFATFST KFLKNGSLWD 

       370        380        390        400        410        420 
LLSSTTTSNF MPMVDVGMDN FDLVKYLMSQ VMLSDDDRFA ALQEYYPQAK KEDWRLWQAG 

       430        440        450        460        470        480 
QRVQIIKRDP KEGGVLRLGT EVVSDKEGTI AALLGASPGA STAAPIMLHL MEKVFKDKVA 

       490        500        510        520        530        540 
SPEWQAKLKT IIPSYGTKLN GNVAATEQEL EFTSRVLQLK YEKPQTAAAA PQAQPQLKPQ 

       550 
PDAKPVADIA L

« Hide

References

[1]"Complete sequence of chromosome of Enterobacter sp. 638."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Kiss H., Brettin T., Bruce D., Detter J.C., Han C., Tapia R., Gilna P., Schmutz J., Larimer F., Land M. expand/collapse author list , Hauser L., Kyrpides N., Kim E., Taghavi S., Newman L., Vangronsveld J., van der Lelie D., Richardson P.
Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 638.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000653 Genomic DNA. Translation: ABP61453.1. Different initiation.
RefSeqYP_001177504.1. NC_009436.1.

3D structure databases

ProteinModelPortalA4WCM3.
ModBaseSearch...

Protein-protein interaction databases

STRINGA4WCM3.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5112740.
GenomeReviewsGene locus Ent638_2788 in contig CP000653_GR.
KEGGent:Ent638_2788.
NMPDRfig|399742.4.peg.2668.
PATRIC20415239. VBIEntSp101211_2938.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0579.
HOGENOMHBG289663.
OMAKKWVPLM.
ProtClustDBPRK05257.

Enzyme and pathway databases

BioCycESP42895:ENT638_2788-MONOMER.

Family and domain databases

HAMAPMF_00212. MQO.
[Tree]
InterProIPR006231. Malate_quinone_OxRdtase.
[Graphical view]
KOK00116.
PANTHERPTHR13847:SF14. PTHR13847:SF14. 1 hit.
PfamPF06039. Mqo. 1 hit.
[Graphical view]
TIGRFAMsTIGR01320. Mal_quin_oxido. 1 hit.
ProtoNetSearch...

Entry information

Entry nameMQO_ENT38
AccessionPrimary (citable) accession number: A4WCM3
Entry history
Integrated into UniProtKB/Swiss-Prot: March 18, 2008
Last sequence update: March 18, 2008
Last modified: January 25, 2012
This is version 37 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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