Skip Header

Contribute Send feedback
Read comments (?) or add your own

A4WCK2 (UXUA_ENT38) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 30. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Mannonate dehydratase
EC=4.2.1.8
Alternative name(s):
D-mannonate hydrolase
Gene names
Name:uxuA
Ordered Locus Names:Ent638_2767
OrganismEnterobacter sp. (strain 638) [Complete proteome] [HAMAP]
Taxonomic identifier399742 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Enterobacter

Protein attributes

Sequence length396 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-mannonate = 2-dehydro-3-deoxy-D-gluconate + H2O. HAMAP MF_00106

Pathway

Carbohydrate metabolism; pentose and glucuronate interconversion. HAMAP MF_00106

Sequence similarities

Belongs to the mannonate dehydratase family.

Ontologies

Keywords
   Molecular functionLyase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processglucuronate catabolic process

Inferred from electronic annotation. Source: InterPro

   Molecular functionmannonate dehydratase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 396396Mannonate dehydratase HAMAP MF_00106
PRO_1000057702

Sequences

Sequence LengthMass (Da)Tools
A4WCK2 [UniParc].

Last modified May 29, 2007. Version 1.
Checksum: 189FB6CC55E4C1D2

FASTA39644,838
        10         20         30         40         50         60 
MEQTWRWYGP NDPVSLDDVR QAGATGVVTA LHHIPNGEVW PVEEIKKRQA VLADKGLTWS 

        70         80         90        100        110        120 
VVESIPVHED IKTHSGQFET WIANYQQSIR NLATCGIDTV CYNFMPILDW TRTDLEYQMP 

       130        140        150        160        170        180 
DGSRALRFDQ IAFAAFELHI LKRPSAEADY SAEEQQQALK WFEDASDADI EKLTRNIIAG 

       190        200        210        220        230        240 
LPGAEEGYTL DQFRARLAEY GDIDKNQLRE NMAYFLRAIV PVAEACGLRL AVHPDDPPRP 

       250        260        270        280        290        300 
ILGLPRIVST IEDMQWLKET VDSINNGFTM CTGSYGVRED NDLVKMIEAF GDRIHFTHLR 

       310        320        330        340        350        360 
ATCRENNPKT FHEAAHLGGD VNMVAVVDAI LSEEQRRKHA GDMRPIPFRP DHGHQMLDDL 

       370        380        390 
RKKTNPGYSA IGRLKGMAEV RGVELALKML KYPELL

« Hide

References

[1]"Complete sequence of chromosome of Enterobacter sp. 638."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Kiss H., Brettin T., Bruce D., Detter J.C., Han C., Tapia R., Gilna P., Schmutz J., Larimer F., Land M. expand/collapse author list , Hauser L., Kyrpides N., Kim E., Taghavi S., Newman L., Vangronsveld J., van der Lelie D., Richardson P.
Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 638.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000653 Genomic DNA. Translation: ABP61432.1.
RefSeqYP_001177483.1. NC_009436.1.

3D structure databases

ProteinModelPortalA4WCK2.
ModBaseSearch...

Protein-protein interaction databases

STRINGA4WCK2.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5112718.
GenomeReviewsGene locus Ent638_2767 in contig CP000653_GR.
KEGGent:Ent638_2767.
NMPDRfig|399742.4.peg.2648.
PATRIC20415195. VBIEntSp101211_2917.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1312.
HOGENOMHBG585927.
OMAVHEEIKT.
PhylomeDBA4WCK2.
ProtClustDBPRK03906.

Enzyme and pathway databases

BioCycESP42895:ENT638_2767-MONOMER.

Family and domain databases

HAMAPMF_00106. UxuA.
[Tree]
InterProIPR004628. Man_deHydtase.
IPR013022. Xyl_isomerase-like_TIM-brl.
[Graphical view]
Gene3DG3DSA:3.20.20.150. Xyl_isomerase-like_TIM-brl. 1 hit.
KOK01686.
PfamPF03786. UxuA. 1 hit.
[Graphical view]
PIRSFPIRSF016049. Man_dehyd. 1 hit.
SUPFAMSSF51658. Xyl_isomerase-like_TIM-brl. 1 hit.
TIGRFAMsTIGR00695. UxuA. 1 hit.
ProtoNetSearch...

Entry information

Entry nameUXUA_ENT38
AccessionPrimary (citable) accession number: A4WCK2
Entry history
Integrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: May 29, 2007
Last modified: January 25, 2012
This is version 30 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents