Reviewed, UniProtKB/Swiss-Prot A4WAF9 (UXAB_ENT38)

Names and origin

Protein names

Recommended name:
    Altronate oxidoreductase
    EC=1.1.1.58
Alternative name(s):
    Tagaturonate reductase
    Tagaturonate dehydrogenase

Gene names

Name:	uxaB
Ordered Locus Names:	Ent638_2013

Organism

Enterobacter sp. (strain 638) [Complete proteome] [HAMAP]

Taxonomic identifier

399742 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Enterobacter

Protein attributes

Sequence length	483 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	D-altronate + NAD(+) = D-tagaturonate + NADH.
Pathway	Carbohydrate metabolism; pentose and glucuronate interconversion.
Sequence similarities	Belongs to the mannitol dehydrogenase family. UxaB subfamily.

Ontologies

Keywords
Ligand	NAD
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	coenzyme binding Inferred from electronic annotation. Source: InterPro tagaturonate reductase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 483	483	Altronate oxidoreductase		PRO_1000061933
Regions
	Nucleotide binding	18 – 29	12	NAD By similarity

Sequences

	Sequence		Length	Mass (Da)
	A4WAF9-1 [UniParc]. Last modified May 29, 2007. Version 1. Checksum: BF0502CD9BFA7D29	FASTA	483	54,527
	10 20 30 40 50 60 MNTLNRRDFP GALYPERIIQ FGEGNFLRAF IDWQIDLLNE HTDLNSGVVI VRPIKSDFPP 70 80 90 100 110 120 SLSVQDGLYT TIIRGLNEQG EAVSDARLIR SVNREISVYS QYDEFLKLAH NPDMRFVFSN 130 140 150 160 170 180 TTEAGISYHA EDKFDDAPAV SYPAKLTRLL FERFSHFNGA ADKGWVIIPC ELIDYNGDAL 190 200 210 220 230 240 RELVLRYAQE WALPAEFTQW LNDANAFCST LVDRIVTGYP RDEVTALETE LGYHDGFLDT 250 260 270 280 290 300 AEHFYLFVIQ GPKSLASELR LDKLSLNVLI VDDIKPYKER KVAILNGAHT ALVPVAFQAG 310 320 330 340 350 360 LDTVGEAMND AEVCAFVEKA IYQEIIPVLD LPKDELESFA SAVTGRFRNP YIKHQLLSIA 370 380 390 400 410 420 LNGMTKYRTR ILPQLLAGQK ATGKLPARLT FALAALIAFY RGERNGESYP VQDDQHWLDR 430 440 450 460 470 480 YQQLWAQHHD KQISTSELVK AVLSVSEHWE QDLTNVSGLV EQVTLDLDAI LLQGMRAAVK QLC

References

[1]

"Complete sequence of chromosome of Enterobacter sp. 638." Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Kiss H., Brettin T., Bruce D., Detter J.C., Han C., Tapia R., Gilna P., Schmutz J., Larimer F., Land M. , Hauser L., Kyrpides N., Kim E., Taghavi S., Newman L., Vangronsveld J., van der Lelie D., Richardson P. Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000653 Genomic DNA. Translation: ABP60689.1.
RefSeq	YP_001176740.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	5113429.
GenomeReviews	Gene locus Ent638_2013 in contig CP000653_GR.
KEGG	ent:Ent638_2013.
NMPDR	fig|399742.4.peg.1969.
Organism-specific databases
CMR	Search...
Family and domain databases
HAMAP	MF_00670. [Tree]
InterPro	IPR013118. Mannitol_DHase_C. IPR013131. Mannitol_DHase_N. [Graphical view]
Pfam	PF01232. Mannitol_dh. 1 hit. PF08125. Mannitol_dh_C. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

UXAB_ENT38

Accession

Primary (citable) accession number: A4WAF9

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 5, 2008
Last sequence update:	May 29, 2007
Last modified:	November 25, 2008
This is version 15 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)