Reviewed, UniProtKB/Swiss-Prot A4W8A9 (6PGL_ENT38)

Names and origin

Protein names

Recommended name:
    6-phosphogluconolactonase
      Short name=6-P-gluconolactonase
    EC=3.1.1.31

Gene names

Name:	pgl
Ordered Locus Names:	Ent638_1258

Organism

Enterobacter sp. (strain 638) [Complete proteome] [HAMAP]

Taxonomic identifier

399742 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Enterobacter

Protein attributes

Sequence length	331 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate By similarity.
Catalytic activity	6-phospho-D-glucono-1,5-lactone + H2O = 6-phospho-D-gluconate. HAMAP MF_01605
Pathway	Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 2/3. HAMAP MF_01605
Sequence similarities	Belongs to the cycloisomerase 2 family.

Ontologies

Keywords
Biological process	Carbohydrate metabolism Glucose metabolism
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glucose metabolic process Inferred from electronic annotation. Source: HAMAP
Molecular function	6-phosphogluconolactonase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 331	331	6-phosphogluconolactonase HAMAP MF_01605		PRO_1000069410

Sequences

	Sequence		Length	Mass (Da)
	A4W8A9-1 [UniParc]. Last modified May 29, 2007. Version 1. Checksum: D136E8BBF5122128	FASTA	331	36,372
	10 20 30 40 50 60 MKQTVYTASP ESQQIHVWRL NTEGSLTLVQ VVDVPGQVQP MVVSPDKRFL YVGVRPEFRV 70 80 90 100 110 120 LAYRISPDDG ALTFAAEAPL PGSPTHISTD RQGRFIFSGS YNAGSVSVTR LEDGIPVETV 130 140 150 160 170 180 DIVEGLEGCH SANISPDNRT LWVPALKQDR ICLFTLSDDG HLQAQNPAEV TTVEGAGPRH 190 200 210 220 230 240 MVFHPNQQYA YVVNELNSSV DVWELHNPNG QIECIQTLDI MPADFADTRW AADIHITPDG 250 260 270 280 290 300 RHLYACDRTS SLITVFSISE DGSVLAIEGF QPTETQPRGF NIDNSGKFLI AAGQKSHHIA 310 320 330 LYEIKGVQGL LEEKGRYAVG QGPMWVVVNA H

References

[1]

"Complete sequence of chromosome of Enterobacter sp. 638." Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Kiss H., Brettin T., Bruce D., Detter J.C., Han C., Tapia R., Gilna P., Schmutz J., Larimer F., Land M. , Hauser L., Kyrpides N., Kim E., Taghavi S., Newman L., Vangronsveld J., van der Lelie D., Richardson P. Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000653 Genomic DNA. Translation: ABP59939.1.
RefSeq	YP_001175990.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	A4W8A9.
Genome annotation databases
GeneID	5114220.
GenomeReviews	Gene locus Ent638_1258 in contig CP000653_GR.
KEGG	ent:Ent638_1258.
NMPDR	fig|399742.4.peg.1263.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	EGCHSAN.
Family and domain databases
HAMAP	MF_01605. [Tree]
InterPro	IPR019405. DUF2394. IPR015943. WD40/YVTN_repeat-like_dom. [Graphical view]
Gene3D	G3DSA:2.130.10.10. WD40/YVTN_repeat-like. 1 hit.
Pfam	PF10282. DUF2394. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

6PGL_ENT38

Accession

Primary (citable) accession number: A4W8A9

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 5, 2008
Last sequence update:	May 29, 2007
Last modified:	November 3, 2009
This is version 14 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)