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A4W8A9 (6PGL_ENT38) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 31. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
6-phosphogluconolactonase
Short name=6-P-gluconolactonase
EC=3.1.1.31
Gene names
Name:pgl
Ordered Locus Names:Ent638_1258
OrganismEnterobacter sp. (strain 638) [Complete proteome] [HAMAP]
Taxonomic identifier399742 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Enterobacter

Protein attributes

Sequence length331 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate By similarity. HAMAP MF_01605

Catalytic activity

6-phospho-D-glucono-1,5-lactone + H2O = 6-phospho-D-gluconate. HAMAP MF_01605

Pathway

Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 2/3. HAMAP MF_01605

Sequence similarities

Belongs to the cycloisomerase 2 family.

Ontologies

Keywords
   Biological processCarbohydrate metabolism
Glucose metabolism
   Molecular functionHydrolase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processpentose-phosphate shunt

Inferred from electronic annotation. Source: InterPro

   Molecular function6-phosphogluconolactonase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 3313316-phosphogluconolactonase HAMAP MF_01605
PRO_1000069410

Sequences

Sequence LengthMass (Da)Tools
A4W8A9 [UniParc].

Last modified May 29, 2007. Version 1.
Checksum: D136E8BBF5122128

FASTA33136,372
        10         20         30         40         50         60 
MKQTVYTASP ESQQIHVWRL NTEGSLTLVQ VVDVPGQVQP MVVSPDKRFL YVGVRPEFRV 

        70         80         90        100        110        120 
LAYRISPDDG ALTFAAEAPL PGSPTHISTD RQGRFIFSGS YNAGSVSVTR LEDGIPVETV 

       130        140        150        160        170        180 
DIVEGLEGCH SANISPDNRT LWVPALKQDR ICLFTLSDDG HLQAQNPAEV TTVEGAGPRH 

       190        200        210        220        230        240 
MVFHPNQQYA YVVNELNSSV DVWELHNPNG QIECIQTLDI MPADFADTRW AADIHITPDG 

       250        260        270        280        290        300 
RHLYACDRTS SLITVFSISE DGSVLAIEGF QPTETQPRGF NIDNSGKFLI AAGQKSHHIA 

       310        320        330 
LYEIKGVQGL LEEKGRYAVG QGPMWVVVNA H

« Hide

References

[1]"Complete sequence of chromosome of Enterobacter sp. 638."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Kiss H., Brettin T., Bruce D., Detter J.C., Han C., Tapia R., Gilna P., Schmutz J., Larimer F., Land M. expand/collapse author list , Hauser L., Kyrpides N., Kim E., Taghavi S., Newman L., Vangronsveld J., van der Lelie D., Richardson P.
Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 638.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000653 Genomic DNA. Translation: ABP59939.1.
RefSeqYP_001175990.1. NC_009436.1.

3D structure databases

ProteinModelPortalA4W8A9.
SMRA4W8A9. Positions 1-331.
ModBaseSearch...

Protein-protein interaction databases

STRINGA4W8A9.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5114220.
GenomeReviewsGene locus Ent638_1258 in contig CP000653_GR.
KEGGent:Ent638_1258.
NMPDRfig|399742.4.peg.1263.
PATRIC20412116. VBIEntSp101211_1394.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG2706.
HOGENOMHBG741123.
OMATLDIMPA.
PhylomeDBA4W8A9.
ProtClustDBPRK11028.

Enzyme and pathway databases

BioCycESP42895:ENT638_1258-MONOMER.

Family and domain databases

HAMAPMF_01605. 6P-gluconolactonase.
[Tree]
InterProIPR022528. 6-phosphogluconolactonase_YbhE.
IPR019405. Lactonase_7-beta_prop.
IPR011045. N2O_reductase_N.
IPR015943. WD40/YVTN_repeat-like_dom.
[Graphical view]
Gene3DG3DSA:2.130.10.10. WD40/YVTN_repeat-like. 1 hit.
KOK07404.
PfamPF10282. Lactonase. 1 hit.
[Graphical view]
SUPFAMSSF50974. N2O_reductase_N. 1 hit.
ProtoNetSearch...

Entry information

Entry name6PGL_ENT38
AccessionPrimary (citable) accession number: A4W8A9
Entry history
Integrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: May 29, 2007
Last modified: January 25, 2012
This is version 31 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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