A4W3G6 (A4W3G6_STRS2) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Thioredoxin reductase RuleBase RU003881
EC=1.8.1.9 RuleBase RU003881

Gene names

Ordered Locus Names:

SSU98_1747

Organism

Streptococcus suis (strain 98HAH33) [Complete proteome] [HAMAP]

Taxonomic identifier

391296 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Lactobacillales › Streptococcaceae › Streptococcus

Protein attributes

Sequence length	305 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Thioredoxin + NADP+ = thioredoxin disulfide + NADPH. RuleBase RU003881
Cofactor	Binds 1 FAD per subunit By similarity. RuleBase RU003881
Sequence similarities	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family. RuleBase RU003880

Ontologies

Keywords
Domain	Redox-active center RuleBase RU003880
Ligand	FAD RuleBase RU003880 Flavoprotein RuleBase RU003880
Molecular function	Oxidoreductase RuleBase RU003880
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	removal of superoxide radicals Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: InterPro
Molecular function	flavin adenine dinucleotide binding Inferred from electronic annotation. Source: InterPro thioredoxin-disulfide reductase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A4W3G6 [UniParc]. Last modified May 29, 2007. Version 1. Checksum: 0428CB1C6333E12E	FASTA	305	33,237
	10 20 30 40 50 60 MYDTVVIGAG PAGMTAALYA GRSNLKVALL ERGIYGGQMN NTAEIENYPG YDHISGPALA 70 80 90 100 110 120 EKMFEPLEKF GVDHIFGTLV RIEEEGQIKK VITEDGVLET KTVVLAMGAK HRLLGIPGED 130 140 150 160 170 180 TYNSRGVSYC AVCDGAFFRG QKLLVVGGGD SAVEEALFLT QFAESVTIVH RRDQLRAQKV 190 200 210 220 230 240 IQDRAFANEK INFIWDSVVE EIKGDDLRVQ SVVIKNVKTE EVSELDFGGV FIYVGLDPMT 250 260 270 280 290 300 DTVADLGITD EAGWVITNEK METTQSGIYA IGDIRQNQLR QIATAVGNGA VAGQEVYNYI TELAE

References

[1]

"A glimpse of streptococcal toxic shock syndrome from comparative genomics of S. suis 2 Chinese isolates." BGI Chen C., Tang J., Dong W., Wang C., Feng Y., Wang J., Zheng F., Pan X., Liu D., Li M., Song Y., Zhu X., Sun H., Feng T., Guo Z., Ju A., Ge J., Dong Y. , Sun W., Jiang Y., Wang J., Yan J., Yang H., Wang X., Gao G.F., Yang R., Wang J., Yu J. PLoS ONE 2:E315-E315(2007) [PubMed: 17375201] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 98HAH33.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000408 Genomic DNA. Translation: ABP92905.1.
RefSeq	YP_001201305.1. NC_009443.1.
3D structure databases
ProteinModelPortal	A4W3G6.
ModBase	Search...
Protein-protein interaction databases
STRING	A4W3G6.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBSTRT00000055954; EBSTRP00000052069; EBSTRG00000055944.
GeneID	5102587.
GenomeReviews	Gene locus SSU98_1747 in contig CP000408_GR.
KEGG	ssv:SSU98_1747.
PATRIC	19779714. VBIStrSui72275_1714.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0492.
GeneTree	EBGT00050000027206.
HOGENOM	HBG669726.
OMA	RMETKIP.
PhylomeDB	A4W3G6.
ProtClustDB	CLSK2458846.
Enzyme and pathway databases
BioCyc	SSUI391296:SSU98_1747-MONOMER.
Family and domain databases
InterPro	IPR013027. FAD_pyr_nucl-diS_OxRdtase. IPR008255. Pyr_nucl-diS_OxRdtase_2_AS. IPR023753. Pyr_nucl-diS_OxRdtase_FAD/NAD. IPR001327. Pyr_OxRdtase_NAD-bd_dom. IPR000103. Pyridine_nuc-diS_OxRdtase_2. IPR005982. Thioredox_Rdtase. [Graphical view]
KO	K00384.
Pfam	PF00070. Pyr_redox. 1 hit. PF07992. Pyr_redox_2. 1 hit. [Graphical view]
PRINTS	PR00368. FADPNR. PR00469. PNDRDTASEII.
TIGRFAMs	TIGR01292. TRX_reduct. 1 hit.
PROSITE	PS00573. PYRIDINE_REDOX_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

A4W3G6_STRS2

Accession

Primary (citable) accession number: A4W3G6

Entry history

Integrated into UniProtKB/TrEMBL:	May 29, 2007
Last sequence update:	May 29, 2007
Last modified:	December 14, 2011
This is version 38 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)