Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

DNA-directed RNA polymerase subunit beta

Gene

rpoB

Organism
Streptococcus suis (strain 98HAH33)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.UniRule annotation

Catalytic activityi

Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Nucleotidyltransferase, Transferase

Keywords - Biological processi

Transcription

Names & Taxonomyi

Protein namesi
Recommended name:
DNA-directed RNA polymerase subunit betaUniRule annotation (EC:2.7.7.6UniRule annotation)
Short name:
RNAP subunit betaUniRule annotation
Alternative name(s):
RNA polymerase subunit betaUniRule annotation
Transcriptase subunit betaUniRule annotation
Gene namesi
Name:rpoBUniRule annotation
Ordered Locus Names:SSU98_0122
OrganismiStreptococcus suis (strain 98HAH33)
Taxonomic identifieri391296 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus

Subcellular locationi

Keywords - Cellular componenti

DNA-directed RNA polymerase

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003004161 – 1190DNA-directed RNA polymerase subunit betaAdd BLAST1190

Interactioni

Subunit structurei

The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliA4VYU3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the RNA polymerase beta chain family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000218611.
KOiK03043.
OMAiYFNPKRY.

Family and domain databases

CDDicd00653. RNA_pol_B_RPB2. 1 hit.
Gene3Di2.30.150.10. 1 hit.
2.40.270.10. 2 hits.
2.40.50.150. 1 hit.
3.90.1110.10. 2 hits.
HAMAPiMF_01321. RNApol_bact_RpoB. 1 hit.
InterProiIPR019462. DNA-dir_RNA_pol_bsu_external_1.
IPR015712. DNA-dir_RNA_pol_su2.
IPR007120. DNA-dir_RNA_pol_su2_6.
IPR010243. RNA_pol_bsu_bac.
IPR007121. RNA_pol_bsu_CS.
IPR007644. RNA_pol_bsu_protrusion.
IPR007642. RNA_pol_Rpb2_2.
IPR007645. RNA_pol_Rpb2_3.
IPR007641. RNA_pol_Rpb2_7.
IPR014724. RNA_pol_RPB2_OB-fold.
[Graphical view]
PANTHERiPTHR20856. PTHR20856. 2 hits.
PfamiPF04563. RNA_pol_Rpb2_1. 1 hit.
PF04561. RNA_pol_Rpb2_2. 2 hits.
PF04565. RNA_pol_Rpb2_3. 1 hit.
PF10385. RNA_pol_Rpb2_45. 1 hit.
PF00562. RNA_pol_Rpb2_6. 1 hit.
PF04560. RNA_pol_Rpb2_7. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02013. rpoB. 1 hit.
PROSITEiPS01166. RNA_POL_BETA. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

A4VYU3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAGHEVQYGK HRTRRSFSRI KEVLDLPNLI EIQTDSFQDF LDYGLKEVFE
60 70 80 90 100
DVLPVSNFTD TMELEFVGYE LKEPKYTLEE ARAHDANYSA PIYVTFRLVN
110 120 130 140 150
KETGEIKTQE VFFGEFPIMT EMGTFIINGA ERIIVSQLVR SPGVYFNDKV
160 170 180 190 200
DKNGKVGYGS TVIPNRGAWL ELETDSKDIA YTRIDRTRKI PFTTLVRALG
210 220 230 240 250
FSGDDEIFDI FGDSELVRNT IEKDIHKNPA DSRTDEALKE IYERLRPGEP
260 270 280 290 300
KTAESSRSLL TARFFDPRRY DLAPVGRYKI NKKLNLRTRL LNQTLAEHVI
310 320 330 340 350
NGETGEIVLE AGTVLSRDVL EKVEAQFDEL NLVEYIPNDN AVLLEPVLLQ
360 370 380 390 400
KFKIVAPKDP ERVVTVIGNA NPAENVRTVT PADILAEMSY FLNLAEGLGR
410 420 430 440 450
VDDIDHLGNR RIRAVGELLA NQVRIGLTRM ERNLRERMSV QDNEVLTPQQ
460 470 480 490 500
IINIRPVTAA IKEFFGSSQL SQFMDQHNPL SELSHKRRLS ALGPGGLTRD
510 520 530 540 550
RAGYEVRDVH YTHYGRMCPI ETPEGPNIGL INNLSSYGHL NKYGFIQTPY
560 570 580 590 600
RKIDRATGTV TNEIVWLTAD EEDAYIVAQS TSPLDENNRF VDKIVMGRHQ
610 620 630 640 650
GNNQEFPADS ADFMDVSPKQ VVAVATACIP FLENDDSNRA LMGANMQRQA
660 670 680 690 700
VPLIDPKAPY VGTGMEYQAA HDSGAAIIAQ HDGKVVYADA DKVEVRREDG
710 720 730 740 750
SLDVYHISKF RRSNSGTAYN QRTLVKLGDI VEKGDFIADG PSMENGEMAL
760 770 780 790 800
GQNPIVAYMT WEGYNFEDAV IMSERLVKDD VYTSVHLEEY ESETRDTKLG
810 820 830 840 850
PEEITREIPN VGEDALRNLD EMGIIRIGAE VKEGDILVGK VTPKGEKDLS
860 870 880 890 900
AEERLLHAIF GDKSREVRDT SLRVPHGADG VVRDVKIFTR ANGDELQSGV
910 920 930 940 950
NMLVRVYIAQ KRKIKVGDKM AGRHGNKGVV SRIVPVEDMP YLPDGTPVDI
960 970 980 990 1000
MLNPLGVPSR MNIGQVMELH LGMAARNLGI HIATPVFDGA SSEDLWSTVK
1010 1020 1030 1040 1050
EAGMDSDAKT ILYDGRTGEP FDNRVSVGVM YMIKLHHMVD DKLHARSVGP
1060 1070 1080 1090 1100
YSLVTQQPLG GKAQFGGQRF GEMEVWALEA YGASNVLQEI LTYKSDDVTG
1110 1120 1130 1140 1150
RLKAYEAITK GKPIPKPGVP ESFRVLVKEL QSLGLDMRVL DEDNNEVELR
1160 1170 1180 1190
DLDEGEDDDI IHVDDLEKAR AKAAADAAAA FAAEEAEGKE
Length:1,190
Mass (Da):132,870
Last modified:May 29, 2007 - v1
Checksum:iC02E5BD057C016F6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000408 Genomic DNA. Translation: ABP91282.1.

Genome annotation databases

EnsemblBacteriaiABP91282; ABP91282; SSU98_0122.
KEGGissv:SSU98_0122.
PATRICi19776454. VBIStrSui72275_0121.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000408 Genomic DNA. Translation: ABP91282.1.

3D structure databases

ProteinModelPortaliA4VYU3.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABP91282; ABP91282; SSU98_0122.
KEGGissv:SSU98_0122.
PATRICi19776454. VBIStrSui72275_0121.

Phylogenomic databases

HOGENOMiHOG000218611.
KOiK03043.
OMAiYFNPKRY.

Family and domain databases

CDDicd00653. RNA_pol_B_RPB2. 1 hit.
Gene3Di2.30.150.10. 1 hit.
2.40.270.10. 2 hits.
2.40.50.150. 1 hit.
3.90.1110.10. 2 hits.
HAMAPiMF_01321. RNApol_bact_RpoB. 1 hit.
InterProiIPR019462. DNA-dir_RNA_pol_bsu_external_1.
IPR015712. DNA-dir_RNA_pol_su2.
IPR007120. DNA-dir_RNA_pol_su2_6.
IPR010243. RNA_pol_bsu_bac.
IPR007121. RNA_pol_bsu_CS.
IPR007644. RNA_pol_bsu_protrusion.
IPR007642. RNA_pol_Rpb2_2.
IPR007645. RNA_pol_Rpb2_3.
IPR007641. RNA_pol_Rpb2_7.
IPR014724. RNA_pol_RPB2_OB-fold.
[Graphical view]
PANTHERiPTHR20856. PTHR20856. 2 hits.
PfamiPF04563. RNA_pol_Rpb2_1. 1 hit.
PF04561. RNA_pol_Rpb2_2. 2 hits.
PF04565. RNA_pol_Rpb2_3. 1 hit.
PF10385. RNA_pol_Rpb2_45. 1 hit.
PF00562. RNA_pol_Rpb2_6. 1 hit.
PF04560. RNA_pol_Rpb2_7. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02013. rpoB. 1 hit.
PROSITEiPS01166. RNA_POL_BETA. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiRPOB_STRS2
AccessioniPrimary (citable) accession number: A4VYU3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 11, 2007
Last sequence update: May 29, 2007
Last modified: November 2, 2016
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.