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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Streptococcus suis (strain 05ZYH33)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligase (EC:6.1.1.19)
Alternative name(s):
Arginyl-tRNA synthetase
Short name:
ArgRS
Gene namesi
Name:argS
Ordered Locus Names:SSU05_2126
OrganismiStreptococcus suis (strain 05ZYH33)
Taxonomic identifieri391295 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
Proteomesi
  • UP000000243 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000181341 – 562Arginine--tRNA ligaseAdd BLAST562

Interactioni

Subunit structurei

Monomer.

Protein-protein interaction databases

STRINGi391295.SSU05_2126.

Structurei

3D structure databases

ProteinModelPortaliA4VYA3.
SMRiA4VYA3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi121 – 131"HIGH" regionAdd BLAST11

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.

Phylogenomic databases

eggNOGiENOG4105C75. Bacteria.
COG0018. LUCA.
HOGENOMiHOG000247211.
KOiK01887.
OMAiNKPLHLG.
OrthoDBiPOG091H01RF.

Family and domain databases

CDDicd00671. ArgRS_core. 1 hit.
Gene3Di3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPiMF_00123. Arg_tRNA_synth. 1 hit.
InterProiView protein in InterPro
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR036695. Arg-tRNA-synth_N_sf.
IPR035684. ArgRS_core.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_Ia_anticodon-bd.
PANTHERiPTHR11956. PTHR11956. 1 hit.
PfamiView protein in Pfam
PF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
PRINTSiPR01038. TRNASYNTHARG.
SMARTiView protein in SMART
SM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
SUPFAMiSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsiTIGR00456. argS. 1 hit.

Sequencei

Sequence statusi: Complete.

A4VYA3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNQKQVIAER LAAILPSLEV EAIYNLLEKP KSSEMGDIAF PAFSLAKVER
60 70 80 90 100
KAPQAIAADI VEKLDTTGFE NVVATGPYVN FFLDKAAISH QVLTDVITEK
110 120 130 140 150
DQYGKLNIGQ GRNVTIDMSS PNIAKPFSVG HLRSTVIGDA LANIHEKLGY
160 170 180 190 200
KPIRINHLGD WGKQFGMLIV AYKLWGDKAA VEADPISELL KLYVRINAEA
210 220 230 240 250
EEKPELDDEA RQWFKKLEDG DPEAHELWQW FRDESLVEFN RIYDKLDVTF
260 270 280 290 300
DSYNGEAFYN DKMDEGIQIL EEKGLLQESK GAKIVDLESY NLPPALIMKT
310 320 330 340 350
DGATLYITRD MATAMYRKRT YDFVKSIYVV GQEQINHFKQ LKAVLKEMDF
360 370 380 390 400
DWSDDMTHIT FGLVTKDKKK LSTRKGNIIL LEPTLDEAIS RALTQIEAKN
410 420 430 440 450
PDLENKEEVA HAVGVGAVKF YDLKTDRDNG YDFDLEAMVS FEGETGPYVQ
460 470 480 490 500
YAYARIQSIL RKANFVPNAE NDYKLADTES WEIIKHIQNF SAVVERAGDK
510 520 530 540 550
FDPSLIAKYA INLAQAFNKY YAHTRILDES PERDSRLALA YATGLVLKEA
560
LRLLGVKAPE KM
Length:562
Mass (Da):63,593
Last modified:May 29, 2007 - v1
Checksum:i16FE2F4A66227197
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000407 Genomic DNA. Translation: ABP91092.1.

Genome annotation databases

EnsemblBacteriaiABP91092; ABP91092; SSU05_2126.
KEGGissu:SSU05_2126.

Similar proteinsi

Entry informationi

Entry nameiSYR_STRSY
AccessioniPrimary (citable) accession number: A4VYA3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: May 29, 2007
Last modified: November 22, 2017
This is version 68 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families