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A4VXW3 (FENR_STRSY) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 56. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Ferredoxin--NADP reductase

Short name=FNR
Short name=Fd-NADP(+) reductase
EC=1.18.1.2
Gene names
Ordered Locus Names:SSU05_1986
OrganismStreptococcus suis (strain 05ZYH33) [Complete proteome] [HAMAP]
Taxonomic identifier391295 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus

Protein attributes

Sequence length322 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

2 reduced ferredoxin + NADP+ + H+ = 2 oxidized ferredoxin + NADPH. HAMAP-Rule MF_01685

Cofactor

Binds 1 FAD per subunit By similarity. HAMAP-Rule MF_01685

Subunit structure

Homodimer By similarity. HAMAP-Rule MF_01685

Sequence similarities

Belongs to the ferredoxin--NADP reductase type 2 family.

Ontologies

Keywords
   LigandFAD
Flavoprotein
NADP
   Molecular functionOxidoreductase
   Technical termComplete proteome
Gene Ontology (GO)
   Molecular_functionNADP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

ferredoxin-NADP+ reductase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

flavin adenine dinucleotide binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 322322Ferredoxin--NADP reductase HAMAP-Rule MF_01685
PRO_0000364974

Sites

Binding site341FAD By similarity
Binding site421FAD By similarity
Binding site471FAD By similarity
Binding site871FAD; via amide nitrogen and carbonyl oxygen By similarity
Binding site1191FAD; via amide nitrogen By similarity
Binding site2791FAD By similarity
Binding site3201FAD By similarity

Sequences

Sequence LengthMass (Da)Tools
A4VXW3 [UniParc].

Last modified May 29, 2007. Version 1.
Checksum: 26C48C9D65A8267F

FASTA32235,109
        10         20         30         40         50         60 
MTQVYDITII GGGPVGLFAA FYAHLRQAKV KIIDSLPQLG GQPAILYPEK AILDIPAFPS 

        70         80         90        100        110        120 
LTGQELTDNL LAQLAPFDTT ICLNETLTAI EPGETITLTT NKGNHQTKTL IIAMGGGAFK 

       130        140        150        160        170        180 
PRPLEIDGAD SFDNVHYHVS NIQQYADKDI VVLGGGDSAV DWSLAFEKIA KTTQIIHRRD 

       190        200        210        220        230        240 
NFRALEHSVE ELKQSSVTIH TPFIPKGLSG ENGRASAIDF DKVKSEDKLT LSFDHLFVNY 

       250        260        270        280        290        300 
GFKSSVGTLK EWGLELNRHR IVVNSKQETS VPGIYAIGDC CFYEGKIDLI ATGLGEAPTA 

       310        320 
VNNAMNYLNP NEKVQPKHST SL 

« Hide

References

[1]"A glimpse of streptococcal toxic shock syndrome from comparative genomics of S. suis 2 Chinese isolates."
Chen C., Tang J., Dong W., Wang C., Feng Y., Wang J., Zheng F., Pan X., Liu D., Li M., Song Y., Zhu X., Sun H., Feng T., Guo Z., Ju A., Ge J., Dong Y. expand/collapse author list , Sun W., Jiang Y., Wang J., Yan J., Yang H., Wang X., Gao G.F., Yang R., Wang J., Yu J.
PLoS ONE 2:E315-E315(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 05ZYH33.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000407 Genomic DNA. Translation: ABP90952.1.
RefSeqYP_001199352.1. NC_009442.1.

3D structure databases

ProteinModelPortalA4VXW3.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING391295.SSU05_1986.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABP90952; ABP90952; SSU05_1986.
GeneID5100010.
KEGGssu:SSU05_1986.
PATRIC19775724. VBIStrSui128929_1955.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0492.
HOGENOMHOG000072909.
KOK00384.
OMAVIVNFGF.
OrthoDBEOG661H9M.

Enzyme and pathway databases

BioCycSSUI391295:GHI8-2046-MONOMER.

Family and domain databases

HAMAPMF_01685. FENR2.
InterProIPR013027. FAD_pyr_nucl-diS_OxRdtase.
IPR022890. Fd--NADP_Rdtase_type_2.
IPR023753. Pyr_nucl-diS_OxRdtase_FAD/NAD.
IPR001327. Pyr_OxRdtase_NAD-bd_dom.
IPR000103. Pyridine_nuc-diS_OxRdtase_2.
[Graphical view]
PfamPF00070. Pyr_redox. 1 hit.
PF07992. Pyr_redox_2. 1 hit.
[Graphical view]
PRINTSPR00368. FADPNR.
PR00469. PNDRDTASEII.
ProtoNetSearch...

Entry information

Entry nameFENR_STRSY
AccessionPrimary (citable) accession number: A4VXW3
Entry history
Integrated into UniProtKB/Swiss-Prot: March 3, 2009
Last sequence update: May 29, 2007
Last modified: May 14, 2014
This is version 56 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families