A4VVS7 (A4VVS7_STRSY) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Phospho-2-dehydro-3-deoxyheptonate aldolase PIRNR PIRNR001361
EC=2.5.1.54 PIRNR PIRNR001361

Alternative name(s):
3-deoxy-D-arabino-heptulosonate 7-phosphate synthase PIRNR PIRNR001361
DAHP synthase PIRNR PIRNR001361
Phospho-2-keto-3-deoxyheptonate aldolase PIRNR PIRNR001361

Gene names

Ordered Locus Names:

SSU05_1250

Organism

Streptococcus suis (strain 05ZYH33) [Complete proteome] [HAMAP]

Taxonomic identifier

391295 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Lactobacillales › Streptococcaceae › Streptococcus

Protein attributes

Sequence length	341 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP) By similarity. PIRNR PIRNR001361
Catalytic activity	Phosphoenolpyruvate + D-erythrose 4-phosphate + H2O = 3-deoxy-D-arabino-hept-2-ulosonate 7-phosphate + phosphate. PIRNR PIRNR001361
Pathway	Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 1/7. PIRNR PIRNR001361
Sequence similarities	Belongs to the class-I DAHP synthase family. PIRNR PIRNR001361

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Aromatic amino acid biosynthesis PIRNR PIRNR001361
Molecular function	Transferase PIRNR PIRNR001361
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	aromatic amino acid family biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	3-deoxy-7-phosphoheptulonate synthase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A4VVS7 [UniParc]. Last modified May 29, 2007. Version 1. Checksum: 43107FA37A208C31	FASTA	341	38,885
	10 20 30 40 50 60 MGIHKRSTSL DIDKVKELSK LEGEFLAAKN QRDEELKRII RGEDDRLLLV IGPCSSDNEE 70 80 90 100 110 120 AVLEYARRLS KLQEEVKDKI FMVMRVYTAK PRTNGEGYKG LVHQPDTSKL PDLINGIAAV 130 140 150 160 170 180 RNLHYRVITE TGLTTADEML YSANYPLVED LVSYHAIGAR SVEDQEHRFV ASGVDMPTGM 190 200 210 220 230 240 KNPTSGNLTV MFNGIYAAQN KQNFIYRDAE VDTDGNPLAH AILRGANTEK GGYEPNYYYD 250 260 270 280 290 300 ILLKTIKQYE QFGLKNPFIV IDTNHDNSGK NYLEQIRIVR QTLINRDWNE AIRKYVRGFM 310 320 330 340 IESYLEDGRQ DSPEVFGKSI TDPCLGWEKT EALIREIHQT V

References

[1]

"A glimpse of streptococcal toxic shock syndrome from comparative genomics of S. suis 2 Chinese isolates." BGI Chen C., Tang J., Dong W., Wang C., Feng Y., Wang J., Zheng F., Pan X., Liu D., Li M., Song Y., Zhu X., Sun H., Feng T., Guo Z., Ju A., Ge J., Dong Y. , Sun W., Jiang Y., Wang J., Yan J., Yang H., Wang X., Gao G.F., Yang R., Wang J., Yu J. PLoS ONE 2:E315-E315(2007) [PubMed: 17375201] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 05ZYH33.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000407 Genomic DNA. Translation: ABP90216.1.
RefSeq	YP_001198616.1. NC_009442.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	A4VVS7.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBSTRT00000053210; EBSTRP00000049397; EBSTRG00000053200.
GeneID	5099005.
GenomeReviews	Gene locus SSU05_1250 in contig CP000407_GR.
KEGG	ssu:SSU05_1250.
PATRIC	19774251. VBIStrSui128929_1223.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0722.
GeneTree	EBGT00050000028141.
HOGENOM	HBG670536.
OMA	MDNSFKL.
ProtClustDB	PRK09261.
Enzyme and pathway databases
BioCyc	SSUI391295:SSU05_1250-MONOMER.
Family and domain databases
InterPro	IPR013785. Aldolase_TIM. IPR006218. DAHP1/KDSA. IPR006219. DHAP_synth_1. [Graphical view]
Gene3D	G3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
KO	K01626.
PANTHER	PTHR21225. AroFGH. 1 hit.
Pfam	PF00793. DAHP_synth_1. 1 hit. [Graphical view]
PIRSF	PIRSF001361. DAHP_synthase. 1 hit.
TIGRFAMs	TIGR00034. AroFGH. 1 hit.
ProtoNet	Search...

Entry information

Entry name

A4VVS7_STRSY

Accession

Primary (citable) accession number: A4VVS7

Entry history

Integrated into UniProtKB/TrEMBL:	May 29, 2007
Last sequence update:	May 29, 2007
Last modified:	January 25, 2012
This is version 31 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)