A4VV69 (LACB_STRSY) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Galactose-6-phosphate isomerase subunit LacB
EC=5.3.1.26

Gene names

Name:	lacB
Ordered Locus Names:	SSU05_1042

Organism

Streptococcus suis (strain 05ZYH33) [Complete proteome] [HAMAP]

Taxonomic identifier

391295 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Firmicutes › Bacilli › Lactobacillales › Streptococcaceae › Streptococcus › Streptococcus suis

Protein attributes

Sequence length	171 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	D-galactose 6-phosphate = D-tagatose 6-phosphate. HAMAP-Rule MF_01556
Pathway	Carbohydrate metabolism; D-galactose 6-phosphate degradation; D-tagatose 6-phosphate from D-galactose 6-phosphate: step 1/1. HAMAP-Rule MF_01556
Subunit structure	Heteromultimeric protein consisting of LacA and LacB By similarity.
Sequence similarities	Belongs to the LacAB/RpiB family.

Ontologies

Keywords
Biological process	Lactose metabolism
Molecular function	Isomerase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	galactose catabolic process Inferred from electronic annotation. Source: UniProtKB-UniPathway lactose catabolic process via tagatose-6-phosphate Inferred from electronic annotation. Source: HAMAP
Molecular_function	galactose-6-phosphate isomerase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 171	171	Galactose-6-phosphate isomerase subunit LacB HAMAP-Rule MF_01556		PRO_1000068934

Sequences

	Sequence		Length	Mass (Da)
	A4VV69 [UniParc]. Last modified May 29, 2007. Version 1. Checksum: 42CB4709CFB782B8	FASTA	171	18,986
	10 20 30 40 50 60 MKIAIGCDHI VTYEKIAVVD YLKNQGYEVL DFGTYDNVRT HYPIFGKKVG EAVVSGQADL 70 80 90 100 110 120 GICICGTGVG INNAVNKVPG VRSALVRDMT SALYAKEELN ANVIGFGGKI TGELLMCDII 130 140 150 160 170 EAFIKAEYKP TEENKRLIEK IAAVETLNQE QANPEFFTEF LEKWDRGEYH D

References

[1]

"A glimpse of streptococcal toxic shock syndrome from comparative genomics of S. suis 2 Chinese isolates." Chen C., Tang J., Dong W., Wang C., Feng Y., Wang J., Zheng F., Pan X., Liu D., Li M., Song Y., Zhu X., Sun H., Feng T., Guo Z., Ju A., Ge J., Dong Y. , Sun W., Jiang Y., Wang J., Yan J., Yang H., Wang X., Gao G.F., Yang R., Wang J., Yu J. PLoS ONE 2:E315-E315(2007) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 05ZYH33.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000407 Genomic DNA. Translation: ABP90008.1.
RefSeq	YP_001198408.1. NC_009442.1.
3D structure databases
ProteinModelPortal	A4VV69.
ModBase	Search...
Protein-protein interaction databases
STRING	391295.SSU05_1042.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ABP90008; ABP90008; SSU05_1042.
GeneID	5100309.
KEGG	ssu:SSU05_1042.
PATRIC	19773855. VBIStrSui128929_1025.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0698.
HOGENOM	HOG000226301.
KO	K01819.
OMA	ETHHANQ.
ProtClustDB	PRK08622.
Enzyme and pathway databases
UniPathway	UPA00702; UER00714.
Family and domain databases
Gene3D	3.40.1400.10. 1 hit.
HAMAP	MF_01556. LacB.
InterPro	IPR004784. LacB. IPR003500. Rib/Gal_isomrase. [Graphical view]
PANTHER	PTHR30345. PTHR30345. 1 hit.
Pfam	PF02502. LacAB_rpiB. 1 hit. [Graphical view]
PIRSF	PIRSF005384. RpiB_LacA_B. 1 hit.
SUPFAM	SSF89623. Rib/Gal_isomrase. 1 hit.
TIGRFAMs	TIGR01119. lacB. 1 hit. TIGR00689. rpiB_lacA_lacB. 1 hit.
ProtoNet	Search...

Entry information

Entry name

LACB_STRSY

Accession

Primary (citable) accession number: A4VV69

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 5, 2008
Last sequence update:	May 29, 2007
Last modified:	May 1, 2013
This is version 41 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program