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Protein

Galactose-6-phosphate isomerase subunit LacB

Gene

lacB

Organism
Streptococcus suis (strain 05ZYH33)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

D-galactose 6-phosphate = D-tagatose 6-phosphate.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. galactose-6-phosphate isomerase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. galactose catabolic process Source: UniProtKB-UniPathway
  2. lactose catabolic process via tagatose-6-phosphate Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Lactose metabolism

Enzyme and pathway databases

BioCyciSSUI391295:GHI8-1102-MONOMER.
UniPathwayiUPA00702; UER00714.

Names & Taxonomyi

Protein namesi
Recommended name:
Galactose-6-phosphate isomerase subunit LacBUniRule annotation (EC:5.3.1.26UniRule annotation)
Gene namesi
Name:lacBUniRule annotation
Ordered Locus Names:SSU05_1042
OrganismiStreptococcus suis (strain 05ZYH33)
Taxonomic identifieri391295 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
ProteomesiUP000000243 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 171171Galactose-6-phosphate isomerase subunit LacBPRO_1000068934Add
BLAST

Interactioni

Subunit structurei

Heteromultimeric protein consisting of LacA and LacB.UniRule annotation

Protein-protein interaction databases

STRINGi391295.SSU05_1042.

Family & Domainsi

Sequence similaritiesi

Belongs to the LacAB/RpiB family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0698.
HOGENOMiHOG000226301.
KOiK01819.
OMAiETHHANQ.
OrthoDBiEOG679TJ4.

Family and domain databases

Gene3Di3.40.1400.10. 1 hit.
HAMAPiMF_01556. LacB.
InterProiIPR004784. LacB.
IPR003500. RpiB_LacA_LacB.
[Graphical view]
PANTHERiPTHR30345. PTHR30345. 1 hit.
PfamiPF02502. LacAB_rpiB. 1 hit.
[Graphical view]
PIRSFiPIRSF005384. RpiB_LacA_B. 1 hit.
SUPFAMiSSF89623. SSF89623. 1 hit.
TIGRFAMsiTIGR01119. lacB. 1 hit.
TIGR00689. rpiB_lacA_lacB. 1 hit.

Sequencei

Sequence statusi: Complete.

A4VV69-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKIAIGCDHI VTYEKIAVVD YLKNQGYEVL DFGTYDNVRT HYPIFGKKVG
60 70 80 90 100
EAVVSGQADL GICICGTGVG INNAVNKVPG VRSALVRDMT SALYAKEELN
110 120 130 140 150
ANVIGFGGKI TGELLMCDII EAFIKAEYKP TEENKRLIEK IAAVETLNQE
160 170
QANPEFFTEF LEKWDRGEYH D
Length:171
Mass (Da):18,986
Last modified:May 29, 2007 - v1
Checksum:i42CB4709CFB782B8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000407 Genomic DNA. Translation: ABP90008.1.
RefSeqiYP_001198408.1. NC_009442.1.

Genome annotation databases

EnsemblBacteriaiABP90008; ABP90008; SSU05_1042.
GeneIDi5100309.
KEGGissu:SSU05_1042.
PATRICi19773855. VBIStrSui128929_1025.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000407 Genomic DNA. Translation: ABP90008.1.
RefSeqiYP_001198408.1. NC_009442.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi391295.SSU05_1042.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABP90008; ABP90008; SSU05_1042.
GeneIDi5100309.
KEGGissu:SSU05_1042.
PATRICi19773855. VBIStrSui128929_1025.

Phylogenomic databases

eggNOGiCOG0698.
HOGENOMiHOG000226301.
KOiK01819.
OMAiETHHANQ.
OrthoDBiEOG679TJ4.

Enzyme and pathway databases

UniPathwayiUPA00702; UER00714.
BioCyciSSUI391295:GHI8-1102-MONOMER.

Family and domain databases

Gene3Di3.40.1400.10. 1 hit.
HAMAPiMF_01556. LacB.
InterProiIPR004784. LacB.
IPR003500. RpiB_LacA_LacB.
[Graphical view]
PANTHERiPTHR30345. PTHR30345. 1 hit.
PfamiPF02502. LacAB_rpiB. 1 hit.
[Graphical view]
PIRSFiPIRSF005384. RpiB_LacA_B. 1 hit.
SUPFAMiSSF89623. SSF89623. 1 hit.
TIGRFAMsiTIGR01119. lacB. 1 hit.
TIGR00689. rpiB_lacA_lacB. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "A glimpse of streptococcal toxic shock syndrome from comparative genomics of S. suis 2 Chinese isolates."
    Chen C., Tang J., Dong W., Wang C., Feng Y., Wang J., Zheng F., Pan X., Liu D., Li M., Song Y., Zhu X., Sun H., Feng T., Guo Z., Ju A., Ge J., Dong Y.
    , Sun W., Jiang Y., Wang J., Yan J., Yang H., Wang X., Gao G.F., Yang R., Wang J., Yu J.
    PLoS ONE 2:E315-E315(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 05ZYH33.

Entry informationi

Entry nameiLACB_STRSY
AccessioniPrimary (citable) accession number: A4VV69
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: May 29, 2007
Last modified: April 1, 2015
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.