Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Peroxyureidoacrylate/ureidoacrylate amidohydrolase RutB

Gene

rutB

Organism
Pseudomonas stutzeri (strain A1501)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2.UniRule annotation

Catalytic activityi

(Z)-3-ureidoacrylate peracid + H2O = (Z)-3-peroxyaminoacrylate + CO2 + NH3.UniRule annotation
(Z)-3-ureidoacrylate + H2O = (Z)-3-aminoacrylate + CO2 + NH3.UniRule annotation
(Z)-2-methyl-ureidoacrylate peracid + H2O = (Z)-2-methyl-peroxyaminoacrylate + CO2 + NH3.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei183 – 1831NucleophileUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Enzyme and pathway databases

BioCyciPSTU379731:GJER-3593-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Peroxyureidoacrylate/ureidoacrylate amidohydrolase RutBUniRule annotation (EC:3.5.1.110UniRule annotation)
Alternative name(s):
Ureidoacrylate amidohydrolaseUniRule annotation
Gene namesi
Name:rutBUniRule annotation
Ordered Locus Names:PST_3598
OrganismiPseudomonas stutzeri (strain A1501)
Taxonomic identifieri379731 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
Proteomesi
  • UP000000233 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 248248Peroxyureidoacrylate/ureidoacrylate amidohydrolase RutBPRO_0000402698Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi379731.PST_3598.

Structurei

3D structure databases

ProteinModelPortaliA4VQH5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the isochorismatase family. RutB subfamily.UniRule annotation

Phylogenomic databases

eggNOGiENOG4106XMA. Bacteria.
COG1335. LUCA.
HOGENOMiHOG000078669.
KOiK09020.
OMAiLAKGGWD.
OrthoDBiPOG091H0ARF.

Family and domain databases

Gene3Di3.40.50.850. 1 hit.
HAMAPiMF_00830. RutB. 1 hit.
InterProiIPR019916. IsoChorase_RutB.
IPR000868. Isochorismatase-like.
[Graphical view]
PfamiPF00857. Isochorismatase. 1 hit.
[Graphical view]
SUPFAMiSSF52499. SSF52499. 1 hit.
TIGRFAMsiTIGR03614. RutB. 1 hit.

Sequencei

Sequence statusi: Complete.

A4VQH5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNAVEQISGY GLSATDEPVQ LPARPEPLAM KASETALIVV DMQNAYASRG
60 70 80 90 100
GYLDLAGFDV SATQPVIAKI RQALNAARAA GMQVIFLQNG WDNGYVEAGG
110 120 130 140 150
PGSPNWHKSN ALKTMRKRPE LAGTLLAKGG WDYALVDELA PQPGDILVPK
160 170 180 190 200
PRYSGFFNSQ LDSTLRARGI RNLVFTGIAT NVCVESTLRD GFHLEYFGVV
210 220 230 240
LADATHQAGP EFAQQAALYN IETFFGWVSS VDAFCQSFAA APEVAVAS
Length:248
Mass (Da):26,558
Last modified:May 29, 2007 - v1
Checksum:iCDB39FF76E601D2F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000304 Genomic DNA. Translation: ABP81226.1.
RefSeqiWP_011914620.1. NC_009434.1.

Genome annotation databases

EnsemblBacteriaiABP81226; ABP81226; PST_3598.
GeneIDi25041184.
KEGGipsa:PST_3598.
PATRICi19967690. VBIPseStu31643_3579.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000304 Genomic DNA. Translation: ABP81226.1.
RefSeqiWP_011914620.1. NC_009434.1.

3D structure databases

ProteinModelPortaliA4VQH5.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi379731.PST_3598.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABP81226; ABP81226; PST_3598.
GeneIDi25041184.
KEGGipsa:PST_3598.
PATRICi19967690. VBIPseStu31643_3579.

Phylogenomic databases

eggNOGiENOG4106XMA. Bacteria.
COG1335. LUCA.
HOGENOMiHOG000078669.
KOiK09020.
OMAiLAKGGWD.
OrthoDBiPOG091H0ARF.

Enzyme and pathway databases

BioCyciPSTU379731:GJER-3593-MONOMER.

Family and domain databases

Gene3Di3.40.50.850. 1 hit.
HAMAPiMF_00830. RutB. 1 hit.
InterProiIPR019916. IsoChorase_RutB.
IPR000868. Isochorismatase-like.
[Graphical view]
PfamiPF00857. Isochorismatase. 1 hit.
[Graphical view]
SUPFAMiSSF52499. SSF52499. 1 hit.
TIGRFAMsiTIGR03614. RutB. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiRUTB_PSEU5
AccessioniPrimary (citable) accession number: A4VQH5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 11, 2011
Last sequence update: May 29, 2007
Last modified: September 7, 2016
This is version 49 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.