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A4VLV9

- A4VLV9_PSEU5

UniProt

A4VLV9 - A4VLV9_PSEU5

Protein

Isocitrate dehydrogenase [NADP]

Gene

icd

Organism
Pseudomonas stutzeri (strain A1501)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 46 (01 Oct 2014)
      Sequence version 1 (29 May 2007)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    Isocitrate + NADP+ = 2-oxoglutarate + CO2 + NADPH.UniRule annotation

    Cofactori

    Binds 1 magnesium or manganese ion per subunit.UniRule annotation

    GO - Molecular functioni

    1. isocitrate dehydrogenase (NADP+) activity Source: UniProtKB-EC
    2. magnesium ion binding Source: InterPro
    3. NAD binding Source: InterPro

    GO - Biological processi

    1. glyoxylate cycle Source: UniProtKB-KW
    2. tricarboxylic acid cycle Source: UniProtKB-KW

    Keywords - Molecular functioni

    OxidoreductaseUniRule annotation

    Keywords - Biological processi

    Glyoxylate bypassUniRule annotation, Tricarboxylic acid cycleUniRule annotation

    Keywords - Ligandi

    ManganeseUniRule annotation, Metal-bindingUniRule annotation, NADPUniRule annotation

    Enzyme and pathway databases

    BioCyciPSTU379731:GJER-2296-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Isocitrate dehydrogenase [NADP]UniRule annotation (EC:1.1.1.42UniRule annotation)
    Gene namesi
    Name:icdImported
    Ordered Locus Names:PST_2301Imported
    OrganismiPseudomonas stutzeri (strain A1501)Imported
    Taxonomic identifieri379731 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
    ProteomesiUP000000233: Chromosome

    Interactioni

    Protein-protein interaction databases

    STRINGi379731.PST_2301.

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the isocitrate and isopropylmalate dehydrogenases family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0538.
    HOGENOMiHOG000021113.
    KOiK00031.
    OMAiCLRPIRY.
    OrthoDBiEOG6SNDTP.

    Family and domain databases

    Gene3Di3.40.718.10. 1 hit.
    InterProiIPR019818. IsoCit/isopropylmalate_DH_CS.
    IPR001804. Isocitrate/isopropylmalate_DH.
    IPR004439. Isocitrate_DH_NADP_dimer_prok.
    IPR024084. IsoPropMal-DH-like_dom.
    [Graphical view]
    PANTHERiPTHR11835. PTHR11835. 1 hit.
    PfamiPF00180. Iso_dh. 1 hit.
    [Graphical view]
    TIGRFAMsiTIGR00183. prok_nadp_idh. 1 hit.
    PROSITEiPS00470. IDH_IMDH. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    A4VLV9-1 [UniParc]FASTAAdd to Basket

    « Hide

    MGYQKIQVPA SGDKITVNAD NTLNVPDNPI IPYIEGDGIG VDISPVMIKV    50
    VDAAVQKAYG GKRKIAWMEI YAGEKATQVY DQDTWLPKET LEAVRDYVVS 100
    IKGPLTTPVG GGIRSLNVAL RQELDLYVCQ RPVRWFTGVP SPVKNPGDVD 150
    MVIFRENSED IYAGVEWKAG SPEAEKVIKF LTEEMGVKKI RFTENCGIGI 200
    KPVSLEGTKR LVRKALQYAV DNDRDSVTFV HKGNIMKFTE GAFKEWGYEV 250
    ARDEFGAELL DGGPWMQFKN PNTGKNIVVK DAIADAMLQQ ILLRPAEYDV 300
    IATLNLNGDY LSDALAAEVG GIGIAPGANL SDTVAMFEAT HGTAPKYAGQ 350
    DKVNPGSLIL SAEMMLRHMG WVEAADLIIK GTEGAIAAKT VTYDFERLME 400
    GAQLMSCSQF GDAMISHM 418
    Length:418
    Mass (Da):45,647
    Last modified:May 29, 2007 - v1
    Checksum:i96272348C893E3AF
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000304 Genomic DNA. Translation: ABP79960.1.
    RefSeqiYP_001172802.1. NC_009434.1.

    Genome annotation databases

    EnsemblBacteriaiABP79960; ABP79960; PST_2301.
    GeneIDi5098381.
    KEGGipsa:PST_2301.
    PATRICi19965094. VBIPseStu31643_2310.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000304 Genomic DNA. Translation: ABP79960.1 .
    RefSeqi YP_001172802.1. NC_009434.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 379731.PST_2301.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABP79960 ; ABP79960 ; PST_2301 .
    GeneIDi 5098381.
    KEGGi psa:PST_2301.
    PATRICi 19965094. VBIPseStu31643_2310.

    Phylogenomic databases

    eggNOGi COG0538.
    HOGENOMi HOG000021113.
    KOi K00031.
    OMAi CLRPIRY.
    OrthoDBi EOG6SNDTP.

    Enzyme and pathway databases

    BioCyci PSTU379731:GJER-2296-MONOMER.

    Family and domain databases

    Gene3Di 3.40.718.10. 1 hit.
    InterProi IPR019818. IsoCit/isopropylmalate_DH_CS.
    IPR001804. Isocitrate/isopropylmalate_DH.
    IPR004439. Isocitrate_DH_NADP_dimer_prok.
    IPR024084. IsoPropMal-DH-like_dom.
    [Graphical view ]
    PANTHERi PTHR11835. PTHR11835. 1 hit.
    Pfami PF00180. Iso_dh. 1 hit.
    [Graphical view ]
    TIGRFAMsi TIGR00183. prok_nadp_idh. 1 hit.
    PROSITEi PS00470. IDH_IMDH. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Complete genome sequence of the metabolically versatile and root-associated nitrogen-fixing bacterium Pseudomonas stutzeri A1501."
      Yan Y., Yang J., Dou Y., Ping S., Chen M., Yao Z., Li H., Lu W., Zhang W., Peng J., Liu W., He S., Geng L., Zhang X., Yang F., Li D., Lin Z., Wang Y.
      , Elmerich C., Lin M., Jin Q.
      Submitted (APR-2006) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: A1501Imported.

    Entry informationi

    Entry nameiA4VLV9_PSEU5
    AccessioniPrimary (citable) accession number: A4VLV9
    Entry historyi
    Integrated into UniProtKB/TrEMBL: May 29, 2007
    Last sequence update: May 29, 2007
    Last modified: October 1, 2014
    This is version 46 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3