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Protein

Leucyl/phenylalanyl-tRNA--protein transferase

Gene

aat

Organism
Pseudomonas stutzeri (strain A1501)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.UniRule annotation

Catalytic activityi

L-leucyl-tRNA(Leu) + [protein] = tRNA(Leu) + L-leucyl-[protein].UniRule annotation
L-phenylalanyl-tRNA(Phe) + [protein] = tRNA + L-phenylalanyl-[protein].UniRule annotation

GO - Molecular functioni

  1. leucyltransferase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. protein catabolic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Acyltransferase, Transferase

Enzyme and pathway databases

BioCyciPSTU379731:GJER-2290-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Leucyl/phenylalanyl-tRNA--protein transferaseUniRule annotation (EC:2.3.2.6UniRule annotation)
Alternative name(s):
L/F-transferaseUniRule annotation
LeucyltransferaseUniRule annotation
PhenyalanyltransferaseUniRule annotation
Gene namesi
Name:aatUniRule annotation
Ordered Locus Names:PST_2295
OrganismiPseudomonas stutzeri (strain A1501)
Taxonomic identifieri379731 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
ProteomesiUP000000233: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 226226Leucyl/phenylalanyl-tRNA--protein transferasePRO_0000304349Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi379731.PST_2295.

Structurei

3D structure databases

ProteinModelPortaliA4VLV3.
SMRiA4VLV3. Positions 2-222.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the L/F-transferase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG2360.
HOGENOMiHOG000102326.
KOiK00684.
OMAiYRQGIFP.
OrthoDBiEOG6WX4R3.

Family and domain databases

HAMAPiMF_00688. Leu_Phe_trans.
InterProiIPR016181. Acyl_CoA_acyltransferase.
IPR004616. Leu/Phe-tRNA_Trfase.
[Graphical view]
PfamiPF03588. Leu_Phe_trans. 1 hit.
[Graphical view]
SUPFAMiSSF55729. SSF55729. 1 hit.
TIGRFAMsiTIGR00667. aat. 1 hit.

Sequencei

Sequence statusi: Complete.

A4VLV3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLTWLKRDDL SFPPLETALR EPNGLLAAGG DLRPERLLAA YRHGCFPWYQ
60 70 80 90 100
EGQPLLWWSP DPRTVLFPDE LHVSRSLRKR MRHGDYRVTF DKAFAEVIQG
110 120 130 140 150
CAGPRSYADG TWITTPMQDA YVRLHEMGVA HSVEVWQQGQ LVGGLYGLAM
160 170 180 190 200
GELFFGESMF SRATDASKVG FVTLVERLRE WGFALIDCQM PTRHLESFGA
210 220
RSIPRAAFAE ALAMHLDRPS AADWRA
Length:226
Mass (Da):25,597
Last modified:May 29, 2007 - v1
Checksum:iAB2AA7EB404569E1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000304 Genomic DNA. Translation: ABP79954.1.
RefSeqiWP_011913421.1. NC_009434.1.
YP_001172796.1. NC_009434.1.

Genome annotation databases

EnsemblBacteriaiABP79954; ABP79954; PST_2295.
GeneIDi5098375.
KEGGipsa:PST_2295.
PATRICi19965082. VBIPseStu31643_2304.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000304 Genomic DNA. Translation: ABP79954.1.
RefSeqiWP_011913421.1. NC_009434.1.
YP_001172796.1. NC_009434.1.

3D structure databases

ProteinModelPortaliA4VLV3.
SMRiA4VLV3. Positions 2-222.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi379731.PST_2295.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABP79954; ABP79954; PST_2295.
GeneIDi5098375.
KEGGipsa:PST_2295.
PATRICi19965082. VBIPseStu31643_2304.

Phylogenomic databases

eggNOGiCOG2360.
HOGENOMiHOG000102326.
KOiK00684.
OMAiYRQGIFP.
OrthoDBiEOG6WX4R3.

Enzyme and pathway databases

BioCyciPSTU379731:GJER-2290-MONOMER.

Family and domain databases

HAMAPiMF_00688. Leu_Phe_trans.
InterProiIPR016181. Acyl_CoA_acyltransferase.
IPR004616. Leu/Phe-tRNA_Trfase.
[Graphical view]
PfamiPF03588. Leu_Phe_trans. 1 hit.
[Graphical view]
SUPFAMiSSF55729. SSF55729. 1 hit.
TIGRFAMsiTIGR00667. aat. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Complete genome sequence of the metabolically versatile and root-associated nitrogen-fixing bacterium Pseudomonas stutzeri A1501."
    Yan Y., Yang J., Dou Y., Ping S., Chen M., Yao Z., Li H., Lu W., Zhang W., Peng J., Liu W., He S., Geng L., Zhang X., Yang F., Li D., Lin Z., Wang Y.
    , Elmerich C., Lin M., Jin Q.
    Submitted (APR-2006) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: A1501.

Entry informationi

Entry nameiLFTR_PSEU5
AccessioniPrimary (citable) accession number: A4VLV3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 11, 2007
Last sequence update: May 29, 2007
Last modified: March 4, 2015
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.