ID   BETB_PSEU5              Reviewed;         490 AA.
AC   A4VKC2;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   29-MAY-2007, sequence version 1.
DT   16-JUN-2009, entry version 15.
DE   RecName: Full=Betaine aldehyde dehydrogenase;
DE            Short=BADH;
DE            EC=1.2.1.8;
GN   Name=betB; OrderedLocusNames=PST_1745;
OS   Pseudomonas stutzeri (strain A1501).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas.
OX   NCBI_TaxID=379731;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Yan Y., Yang J., Dou Y., Ping S., Chen M., Yao Z., Li H., Lu W.,
RA   Zhang W., Peng J., Liu W., He S., Geng L., Zhang X., Yang F., Li D.,
RA   Lin Z., Wang Y., Elmerich C., Lin M., Jin Q.;
RT   "Complete genome sequence of the metabolically versatile and root-
RT   associated nitrogen-fixing bacterium Pseudomonas stutzeri A1501.";
RL   Submitted (APR-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY: Betaine aldehyde + NAD(+) + H(2)O = betaine +
CC       NADH.
CC   -!- PATHWAY: Amine and polyamine biosynthesis; betaine biosynthesis
CC       via choline pathway; betaine from betaine aldehyde: step 1/1.
CC   -!- SIMILARITY: Belongs to the aldehyde dehydrogenase family.
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DR   EMBL; CP000304; ABP79423.1; -; Genomic_DNA.
DR   RefSeq; YP_001172265.1; -.
DR   GeneID; 5097829; -.
DR   GenomeReviews; CP000304_GR; PST_1745.
DR   KEGG; psa:PST_1745; -.
DR   OMA; A4VKC2; IERARIM.
DR   GO; GO:0008802; F:betaine-aldehyde dehydrogenase activity; IEA:HAMAP.
DR   GO; GO:0019285; P:glycine betaine biosynthetic process from c...; IEA:HAMAP.
DR   GO; GO:0055114; P:oxidation reduction; IEA:UniProtKB-KW.
DR   HAMAP; MF_00804; -; 1.
DR   InterPro; IPR016160; Ald_DH_CS.
DR   InterPro; IPR016162; Ald_DH_N.
DR   InterPro; IPR015590; Aldehyde_DH.
DR   InterPro; IPR011264; Betaine_Ald_DH.
DR   Gene3D; G3DSA:3.40.605.10; Aldehyde_dehydrogenase_N; 1.
DR   PANTHER; PTHR11699; Aldehyde_dehyd; 1.
DR   Pfam; PF00171; Aldedh; 1.
DR   TIGRFAMs; TIGR01804; BADH; 1.
DR   PROSITE; PS00070; ALDEHYDE_DEHYDR_CYS; 1.
DR   PROSITE; PS00687; ALDEHYDE_DEHYDR_GLU; 1.
PE   3: Inferred from homology;
KW   Complete proteome; NAD; Oxidoreductase.
FT   CHAIN         1    490       Betaine aldehyde dehydrogenase.
FT                                /FTId=PRO_1000047051.
FT   NP_BIND     229    234       NAD (By similarity).
FT   ACT_SITE    252    252       By similarity.
FT   ACT_SITE    286    286       By similarity.
SQ   SEQUENCE   490 AA;  52389 MW;  FD5970D8BC7E75E1 CRC64;
     MARFPRQQLY IHGAYVDASS NQTFESINPA NGEVLAEVAE AGAADLERAV ESAEQGQRIW
     AALTGIERAR IMRRAVDLLR ERNDELALLE TLDTGKPLSE TRSVDIITGA DVLEYYAGLA
     PAIEGEQIPL RDSSFVYTRR EPLGVVAGIG AWNYPIQIAL WKAAPALAAG NAMIFKPSEV
     TPLSALRLAE IFSEAGLPDG VFNVLTGSGA GVGALITEHP RIAKVSFTGG VATGKKVMAS
     AAGSSLKDVT MELGGKSPLI VCEDADLDRA ADIAVMANFF SSGQVCTNGT RVFIPAGLKA
     SFEAKLLERV QRVRLGDPQQ EATNFGPLVS FAHMDKVLDY IAQGKAAGAR ILCGGERVTE
     GEYARGAFVA PTIFSDCSDD MSIVREEIFG PVLSLLEYQG EDEAIRRAND TEYGLAAGVV
     TPDLARAHRI IHRLEAGICW INTWGESPAQ MPVGGYKQSG IGRENGIASL AHYTRVKSVQ
     VELGEFASVF
//