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A4VKC2 (BETB_PSEU5) Reviewed, UniProtKB/Swiss-Prot

Last modified December 14, 2011. Version 34. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Betaine aldehyde dehydrogenase
Short name=BADH
EC=1.2.1.8
Gene names
Name:betB
Ordered Locus Names:PST_1745
OrganismPseudomonas stutzeri (strain A1501) [Complete proteome] [HAMAP]
Taxonomic identifier379731 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Pseudomonadaceae › Pseudomonas

Protein attributes

Sequence length490 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Betaine aldehyde + NAD+ + H2O = betaine + NADH. HAMAP MF_00804

Pathway

Amine and polyamine biosynthesis; betaine biosynthesis via choline pathway; betaine from betaine aldehyde: step 1/1. HAMAP MF_00804

Sequence similarities

Belongs to the aldehyde dehydrogenase family.

Ontologies

Keywords
   LigandNAD
   Molecular functionOxidoreductase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processbetaine biosynthetic process

Inferred from electronic annotation. Source: InterPro

   Molecular functionbetaine-aldehyde dehydrogenase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 490490Betaine aldehyde dehydrogenase HAMAP MF_00804
PRO_1000047051

Regions

Nucleotide binding229 – 2346NAD By similarity

Sites

Active site2521 By similarity
Active site2861 By similarity

Sequences

Sequence LengthMass (Da)Tools
A4VKC2 [UniParc].

Last modified May 29, 2007. Version 1.
Checksum: FD5970D8BC7E75E1

FASTA49052,389
        10         20         30         40         50         60 
MARFPRQQLY IHGAYVDASS NQTFESINPA NGEVLAEVAE AGAADLERAV ESAEQGQRIW 

        70         80         90        100        110        120 
AALTGIERAR IMRRAVDLLR ERNDELALLE TLDTGKPLSE TRSVDIITGA DVLEYYAGLA 

       130        140        150        160        170        180 
PAIEGEQIPL RDSSFVYTRR EPLGVVAGIG AWNYPIQIAL WKAAPALAAG NAMIFKPSEV 

       190        200        210        220        230        240 
TPLSALRLAE IFSEAGLPDG VFNVLTGSGA GVGALITEHP RIAKVSFTGG VATGKKVMAS 

       250        260        270        280        290        300 
AAGSSLKDVT MELGGKSPLI VCEDADLDRA ADIAVMANFF SSGQVCTNGT RVFIPAGLKA 

       310        320        330        340        350        360 
SFEAKLLERV QRVRLGDPQQ EATNFGPLVS FAHMDKVLDY IAQGKAAGAR ILCGGERVTE 

       370        380        390        400        410        420 
GEYARGAFVA PTIFSDCSDD MSIVREEIFG PVLSLLEYQG EDEAIRRAND TEYGLAAGVV 

       430        440        450        460        470        480 
TPDLARAHRI IHRLEAGICW INTWGESPAQ MPVGGYKQSG IGRENGIASL AHYTRVKSVQ 

       490 
VELGEFASVF

« Hide

References

[1]"Complete genome sequence of the metabolically versatile and root-associated nitrogen-fixing bacterium Pseudomonas stutzeri A1501."
Yan Y., Yang J., Dou Y., Ping S., Chen M., Yao Z., Li H., Lu W., Zhang W., Peng J., Liu W., He S., Geng L., Zhang X., Yang F., Li D., Lin Z., Wang Y. expand/collapse author list , Elmerich C., Lin M., Jin Q.
Submitted (APR-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: A1501.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000304 Genomic DNA. Translation: ABP79423.1.
RefSeqYP_001172265.1. NC_009434.1.

3D structure databases

ProteinModelPortalA4VKC2.
ModBaseSearch...

Protein-protein interaction databases

STRINGA4VKC2.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5097829.
GenomeReviewsGene locus PST_1745 in contig CP000304_GR.
KEGGpsa:PST_1745.
PATRIC19963961. VBIPseStu31643_1755.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1012.
HOGENOMHBG752218.
OMAAHRTIHR.
PhylomeDBA4VKC2.
ProtClustDBPRK13252.

Enzyme and pathway databases

BioCycPSTU379731:PST_1745-MONOMER.

Family and domain databases

HAMAPMF_00804. BADH.
[Tree]
InterProIPR016161. Ald_DH/histidinol_DH.
IPR016163. Ald_DH_C.
IPR016160. Ald_DH_CS.
IPR016162. Ald_DH_N.
IPR015590. Aldehyde_DH_dom.
IPR011264. Betaine_Ald_DH.
[Graphical view]
Gene3DG3DSA:3.40.309.10. Aldehyde_dehydrogenase_C. 1 hit.
G3DSA:3.40.605.10. Aldehyde_dehydrogenase_N. 1 hit.
KOK00130.
PfamPF00171. Aldedh. 1 hit.
[Graphical view]
SUPFAMSSF53720. Aldehyde_DH/Histidinol_DH. 1 hit.
TIGRFAMsTIGR01804. BADH. 1 hit.
PROSITEPS00070. ALDEHYDE_DEHYDR_CYS. 1 hit.
PS00687. ALDEHYDE_DEHYDR_GLU. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameBETB_PSEU5
AccessionPrimary (citable) accession number: A4VKC2
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: May 29, 2007
Last modified: December 14, 2011
This is version 34 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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