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Protein

Ribonuclease HII

Gene

rnhB

Organism
Pseudomonas stutzeri (strain A1501)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.UniRule annotation

Catalytic activityi

Endonucleolytic cleavage to 5'-phosphomonoester.UniRule annotation

Cofactori

Mn2+UniRule annotation, Mg2+UniRule annotationNote: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi18Divalent metal cationUniRule annotation1
Metal bindingi19Divalent metal cationUniRule annotation1
Metal bindingi110Divalent metal cationUniRule annotation1

GO - Molecular functioni

Keywordsi

Molecular functionEndonuclease, Hydrolase, Nuclease
LigandManganese, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Ribonuclease HIIUniRule annotation (EC:3.1.26.4UniRule annotation)
Short name:
RNase HIIUniRule annotation
Gene namesi
Name:rnhBUniRule annotation
Ordered Locus Names:PST_1551
OrganismiPseudomonas stutzeri (strain A1501)
Taxonomic identifieri379731 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
Proteomesi
  • UP000000233 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000311841 – 212Ribonuclease HIIAdd BLAST212

Interactioni

Protein-protein interaction databases

STRINGi379731.PST_1551.

Structurei

3D structure databases

ProteinModelPortaliA4VJT5.
SMRiA4VJT5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the RNase HII family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4108UH2. Bacteria.
COG0164. LUCA.
HOGENOMiHOG000100288.
KOiK03470.
OMAiNILHASM.
OrthoDBiPOG091H011N.

Family and domain databases

CDDicd07182. RNase_HII_bacteria_HII_like. 1 hit.
Gene3Di3.30.420.10. 1 hit.
HAMAPiMF_00052_B. RNase_HII_B. 1 hit.
InterProiView protein in InterPro
IPR022898. RNase_HII.
IPR001352. RNase_HII/HIII.
IPR024567. RNase_HII/HIII_dom.
IPR012337. RNaseH-like_dom.
PANTHERiPTHR10954. PTHR10954. 1 hit.
PTHR10954:SF15. PTHR10954:SF15. 1 hit.
PfamiView protein in Pfam
PF01351. RNase_HII. 1 hit.
SUPFAMiSSF53098. SSF53098. 1 hit.

Sequencei

Sequence statusi: Complete.

A4VJT5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQFGLDFNLV EELVAGVDEV GRGPLCGPVV TAAVILDPAR PIEGLNDSKK
60 70 80 90 100
LTEARREALF DEIREKAVAW CIARAEVEEI DQLNILHATM LAMQRAVEGL
110 120 130 140 150
SVTPRLALID GNRCPQLAVP SAPVIQGDAQ VPAIAAASIL AKVSRDREMQ
160 170 180 190 200
ALDLCYPGYG LAGHKGYPTP SHLEALRRLG PTPIHRRSFA PVRAMLEQVS
210
IEVEVPASVL LV
Length:212
Mass (Da):22,869
Last modified:May 29, 2007 - v1
Checksum:i2AB05543A0F07456
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000304 Genomic DNA. Translation: ABP79236.1.
RefSeqiWP_011912714.1. NC_009434.1.

Genome annotation databases

EnsemblBacteriaiABP79236; ABP79236; PST_1551.
GeneIDi28546085.
KEGGipsa:PST_1551.

Similar proteinsi

Entry informationi

Entry nameiRNH2_PSEU5
AccessioniPrimary (citable) accession number: A4VJT5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: May 29, 2007
Last modified: September 27, 2017
This is version 63 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families