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A4VHV6 (TYPH_PSEU5) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 44. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Putative thymidine phosphorylase

EC=2.4.2.4
Alternative name(s):
TdRPase
Gene names
Ordered Locus Names:PST_0860
OrganismPseudomonas stutzeri (strain A1501) [Complete proteome] [HAMAP]
Taxonomic identifier379731 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas

Protein attributes

Sequence length526 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Thymidine + phosphate = thymine + 2-deoxy-alpha-D-ribose 1-phosphate. HAMAP-Rule MF_00703

Sequence similarities

Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. Type 2 subfamily.

Sequence caution

The sequence ABP78557.1 differs from that shown. Reason: Erroneous initiation.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 526526Putative thymidine phosphorylase HAMAP-Rule MF_00703
PRO_0000314707

Sequences

Sequence LengthMass (Da)Tools
A4VHV6 [UniParc].

Last modified January 15, 2008. Version 2.
Checksum: 8919244A6B4B3662

FASTA52656,665
        10         20         30         40         50         60 
MTSISSDTPL NGKAPVHLAL RRVAIDTYRE NVAYLHRDCA ACRAEGFQAL AKVEIRVNGR 

        70         80         90        100        110        120 
RILASLNLVD DPSIVGCDEL GLSEDAFAQL GAEAGVPAAI AQAEPAASIP ALHRKIAGER 

       130        140        150        160        170        180 
LNRDDFLAIM RDIAEHRYSK IELTAFVVAC NQGELDREEV FFLTDAMIRV GRRLDWREHP 

       190        200        210        220        230        240 
VVDKHCIGGI PGNRTSMLVV PIVAAHGMLC PKTSSRAITS PAGTADTMEV LANVELPFER 

       250        260        270        280        290        300 
LCEMVREERG CLAWGGSSDL SPADDVLIAV ERPLSIDSPG QMVASILSKK IAAGSTHLLL 

       310        320        330        340        350        360 
DIPIGPTAKV RSMAEAQRLR KLFEFVATRL GLTLDVVITD GRQPIGNGIG PVLEARDVIQ 

       370        380        390        400        410        420 
VLQNDPAAPI DLRQKALRLA GRMLEFDPDV RGGDGYAIAR DILDSGRALK KMRSIIAAQG 

       430        440        450        460        470        480 
GKPFDHNHPP LARLSFDVLA DCDAVVTGID NLQLARIARL AGAPKVQGAG VDILRKLGEP 

       490        500        510        520 
VRAGDCLYRV YADFPADLAF ARQATERASG VSLGSPEQVP TVFVEF 

« Hide

References

[1]"Complete genome sequence of the metabolically versatile and root-associated nitrogen-fixing bacterium Pseudomonas stutzeri A1501."
Yan Y., Yang J., Dou Y., Ping S., Chen M., Yao Z., Li H., Lu W., Zhang W., Peng J., Liu W., He S., Geng L., Zhang X., Yang F., Li D., Lin Z., Wang Y. expand/collapse author list , Elmerich C., Lin M., Jin Q.
Submitted (APR-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: A1501.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000304 Genomic DNA. Translation: ABP78557.1. Different initiation.
RefSeqYP_001171399.1. NC_009434.1.

3D structure databases

ProteinModelPortalA4VHV6.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING379731.PST_0860.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABP78557; ABP78557; PST_0860.
GeneID5098530.
KEGGpsa:PST_0860.
PATRIC19962135. VBIPseStu31643_0854.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0213.
HOGENOMHOG000252767.
KOK00758.
OrthoDBEOG61ZTGG.
ProtClustDBPRK04350.

Enzyme and pathway databases

BioCycPSTU379731:GJER-861-MONOMER.

Family and domain databases

Gene3D3.40.1030.10. 1 hit.
3.90.1170.30. 1 hit.
HAMAPMF_00703. Thymid_phosp_2.
InterProIPR000312. Glycosyl_Trfase_fam3.
IPR017459. Glycosyl_Trfase_fam3_N_dom.
IPR013102. PYNP_C.
IPR000053. Pyrmidine_PPase.
IPR017872. Pyrmidine_PPase_CS.
IPR028579. Thym_Pase_Put.
IPR013466. Thymidine/AMP_Pase.
[Graphical view]
PANTHERPTHR10515. PTHR10515. 1 hit.
PfamPF02885. Glycos_trans_3N. 1 hit.
PF00591. Glycos_transf_3. 1 hit.
PF07831. PYNP_C. 1 hit.
[Graphical view]
PIRSFPIRSF000478. TP_PyNP. 1 hit.
SMARTSM00941. PYNP_C. 1 hit.
[Graphical view]
SUPFAMSSF47648. SSF47648. 1 hit.
SSF52418. SSF52418. 1 hit.
SSF54680. SSF54680. 1 hit.
TIGRFAMsTIGR02645. ARCH_P_rylase. 1 hit.
PROSITEPS00647. THYMID_PHOSPHORYLASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameTYPH_PSEU5
AccessionPrimary (citable) accession number: A4VHV6
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: January 15, 2008
Last modified: February 19, 2014
This is version 44 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families