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Protein

Bis(5'-nucleosyl)-tetraphosphatase, symmetrical

Gene

apaH

Organism
Pseudomonas stutzeri (strain A1501)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.UniRule annotation

Catalytic activityi

P1,P4-bis(5'-adenosyl) tetraphosphate + H2O = 2 ADP.UniRule annotation

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase

Enzyme and pathway databases

BioCyciPSTU379731:G1G6D-755-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Bis(5'-nucleosyl)-tetraphosphatase, symmetricalUniRule annotation (EC:3.6.1.41UniRule annotation)
Alternative name(s):
Ap4A hydrolaseUniRule annotation
Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolaseUniRule annotation
Diadenosine tetraphosphataseUniRule annotation
Gene namesi
Name:apaHUniRule annotation
Ordered Locus Names:PST_0724
OrganismiPseudomonas stutzeri (strain A1501)
Taxonomic identifieri379731 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
Proteomesi
  • UP000000233 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000120831 – 275Bis(5'-nucleosyl)-tetraphosphatase, symmetricalAdd BLAST275

Interactioni

Protein-protein interaction databases

STRINGi379731.PST_0724

Structurei

3D structure databases

ProteinModelPortaliA4VHH8
SMRiA4VHH8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the Ap4A hydrolase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105DDT Bacteria
COG0639 LUCA
HOGENOMiHOG000251871
KOiK01525
OMAiMPWFDVP
OrthoDBiPOG091H0691

Family and domain databases

CDDicd07422 MPP_ApaH, 1 hit
Gene3Di3.60.21.10, 1 hit
HAMAPiMF_00199 ApaH, 1 hit
InterProiView protein in InterPro
IPR004617 ApaH
IPR004843 Calcineurin-like_PHP_ApaH
IPR029052 Metallo-depent_PP-like
PfamiView protein in Pfam
PF00149 Metallophos, 1 hit
PIRSFiPIRSF000903 B5n-ttraPtase_sm, 1 hit
TIGRFAMsiTIGR00668 apaH, 1 hit

Sequencei

Sequence statusi: Complete.

A4VHH8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTTYAVGDLQ GCLEPLTCLL ERVDFSPSRD CLWLAGDLVN RGPQSLEALR
60 70 80 90 100
FVRDLESSAI TVLGNHDLHL LAVAHNIERM RKSDTLQAIL DAPDRADLID
110 120 130 140 150
WLRQQKLIHY DAERHTAMVH AGIPPQWSLE KALRRAAEVE QALQDDALLL
160 170 180 190 200
PFLDGMYGNQ PAKWNKELHG VPRLRLITNY FTRMRFCKAD GTLDLDAKEG
210 220 230 240 250
ADSAPAGYAP WFSHASRKTR NVKLIFGHWA ALEGQCDEPN VFALDTGCVW
260 270
GNAMTLMNLD SGEMHRCECE HGKPA
Length:275
Mass (Da):30,842
Last modified:May 29, 2007 - v1
Checksum:i745B832B97C6C9C0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000304 Genomic DNA Translation: ABP78429.1
RefSeqiWP_011911936.1, NC_009434.1

Genome annotation databases

EnsemblBacteriaiABP78429; ABP78429; PST_0724
KEGGipsa:PST_0724

Similar proteinsi

Entry informationi

Entry nameiAPAH_PSEU5
AccessioniPrimary (citable) accession number: A4VHH8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: May 29, 2007
Last modified: March 28, 2018
This is version 70 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health