Unreviewed, UniProtKB/TrEMBL A4V464 (A4V464_DROME)

Names and origin

Protein names

Submitted name:
    CG7033, isoform C EMBL AAO41641.1
    EC=3.6.1.3

Gene names

ORF Names:

CG7033 FlyBase FBgn0030086, Dmel_CG7033 EMBL AAO41641.1

Organism

Drosophila melanogaster (Fruit fly) [Complete proteome]

Taxonomic identifier

7227 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora

Protein attributes

Sequence length	533 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Sequence similarities

Belongs to the TCP-1 chaperonin family. RuleBase RU004187V2

Ontologies

Keywords
Cellular component	Cytoplasm Spearmint SPM017998
Ligand	ATP-binding RuleBase RU003319V0 Nucleotide-binding
Molecular function	Chaperone RuleBase RU003319V0 Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	protein folding Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	ATP binding Inferred from electronic annotation. Source: InterPro ATPase activity, uncoupled Inferred from electronic annotation. Source: EC unfolded protein binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	A4V464-1 [UniParc]. Last modified December 4, 2007. Version 1. Checksum: 8BBDD0219C7D3BE1	FASTA	533	57,804
	10 20 30 40 50 60 MSLNPVRVLK NEAQEEKAEM ARLSSFIGAI AIGDLVKSTL GPKGMDKILV ATGRNAGHVE 70 80 90 100 110 120 VTNDGATILR AVGVDNPAAK ILVDMSRVQD EEVGDGTTSV TVLASELLRE AEKLVEQKLH 130 140 150 160 170 180 PQIIVSGWRQ ATQVALEALT AAAQDNSSSD EKFRNDLLNI ARTTLSSKIL HQHKDFFANL 190 200 210 220 230 240 AVDAVMRLKG SGELKSIQII KKSGGTLGDS FLDEGFLLDK KPGVHQPQRI ENARILIANT 250 260 270 280 290 300 PMDTDKIKVF GSSIKVDSLA KIADLEMAEK EKMKEKVDKI LKHKCNVFIN RQLIYNYPEQ 310 320 330 340 350 360 LFADARVMSI EHADFDGIER LAYCTGGEIV STFENPSLVK LGECDVIEQV MIGEDTLLRF 370 380 390 400 410 420 SGVKLGEACT IVIRGATQQI LDEADRSLHD ALCVLAATVK ESRIIFGGGC SEALMATAVL 430 440 450 460 470 480 KKAAETPGKE AIAIEAFARA LLSLPTAIAD NAGYDSAQLV SELRAGHAQG KQTLGLDMEL 490 500 510 520 530 GKVADVRELG ITESFAVKRQ VLMSASEAAE MILRVDNIIR CAPRRRVPDR GYC

References

[1]

"The genome sequence of Drosophila melanogaster." Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., Sutton G.G., Wortman J.R., Yandell M.D. , Zhang Q., Chen L.X., Brandon R.C., Rogers Y.-H.C., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Miklos G.L.G., Abril J.F., Agbayani A., An H.-J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., Harris N.L., Harvey D.A., Heiman T.J., Hernandez J.R., Houck J., Hostin D., Houston K.A., Howland T.J., Wei M.-H., Ibegwam C., Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D., Kraft C.L., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A., Li J.H., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., Reinert K., Remington K., Saunders R.D.C., Scheeler F., Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.J., Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.-Y., Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., Woodage T., Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.-F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S.C., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C. Science 287:2185-2195(2000) [PubMed: 10731132] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Berkeley.

[2]

"Annotation of the Drosophila melanogaster euchromatic genome: a systematic review." Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S., Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E., Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P., Bettencourt B.R., Celniker S.E., de Grey A.D.N.J. , Drysdale R.A., Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M., Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E. Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002) [PubMed: 12537572] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Berkeley.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE014298 Genomic DNA. Translation: AAO41641.1.
RefSeq	NP_788888.1.
UniGene	Dm.113
3D structure databases
ModBase	Search...
Proteomic databases
PRIDE	A4V464.
Genome annotation databases
GeneID	31838.
Organism-specific databases
FlyBase	FBgn0030086. CG7033.
Family and domain databases
InterPro	IPR012716. Chap_CCT_beta. IPR017998. Chaperone_TCP-1. IPR002194. Chaperonin_TCP-1_CS. IPR002423. Cpn60/TCP-1. IPR000629. RNA-helicase_DEAD-box_CS. [Graphical view]
PANTHER	PTHR11353:SF23. Chap_CCT_beta. 1 hit. PTHR11353. Cpn60/TCP-1. 1 hit.
Pfam	PF00118. Cpn60_TCP1. 1 hit. [Graphical view]
PRINTS	PR00304. TCOMPLEXTCP1.
TIGRFAMs	TIGR02341. chap_CCT_beta. 1 hit.
PROSITE	PS00039. DEAD_ATP_HELICASE. 1 hit. Uncertain. PS00750. TCP1_1. 1 hit. PS00751. TCP1_2. 1 hit. PS00995. TCP1_3. 1 hit. [Graphical view]
ProtoNet	Search...
Other Resources
NextBio	775573.

Entry information

Entry name

A4V464_DROME

Accession

Primary (citable) accession number: A4V464

Entry history

Integrated into UniProtKB/TrEMBL:	December 4, 2007
Last sequence update:	December 4, 2007
Last modified:	March 3, 2009
This is version 16 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)